Mesalamine is used to treat the symptoms of a bowel disease called ulcerative colitis. These symptoms include diarrhea, rectal bleeding, inflammation, tissue damage, and stomach pain. There are multiple brand names for Mesalamine, such as Lialda and Apriso. Mesalamine is a generic drug, so it should be cheaper than its brand-name counterpart. On average, the cost of a one-month supply of Mesalamine is $1,225.13. If you use a Mesalamine coupon by SingleCare, you can reduce your Mesalamine cost to as little as $79.32 per 120, 1.2gm tablet delayed releases. Participating pharmacies include CVS, Walmart, Kroger, Walgreens, and more. You can ask your local pharmacy to save your SingleCare Mesalamine discount card for future refills and pharmaceutical purchases too.
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SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.
Prices updated: 12/05/2025
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Mesalamine is used to treat the symptoms of a bowel disease called ulcerative colitis. These symptoms include diarrhea, rectal bleeding, inflammation, tissue damage, and stomach pain. There are multiple brand names for Mesalamine, such as Lialda and Apriso. Mesalamine is a generic drug, so it should be cheaper than its brand-name counterpart. On average, the cost of a one-month supply of Mesalamine is $1,225.13. If you use a Mesalamine coupon by SingleCare, you can reduce your Mesalamine cost to as little as $79.32 per 120, 1.2gm tablet delayed releases. Participating pharmacies include CVS, Walmart, Kroger, Walgreens, and more. You can ask your local pharmacy to save your SingleCare Mesalamine discount card for future refills and pharmaceutical purchases too.
Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.
| Pharmacy | Mesalamine Retail Price | Mesalamine SingleCare Price |
|---|---|---|
| CVS Pharmacy | $327.60 | $136.80 |
| Walmart | $394.80 | $331.20 |
| Walgreens | $392.15 | $263.18 |
| Kroger Pharmacy | $1277.20 | $230.40 |
| Albertsons Pharmacy | $1010.40 | $312.00 |
These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.
Mesalamine is used to treat the symptoms of a bowel disease called ulcerative colitis. These symptoms include diarrhea, rectal bleeding, inflammation, tissue damage, and stomach pain. There are multiple brand names for Mesalamine, such as Lialda and Apriso. Mesalamine is a generic drug, so it should be cheaper than its brand-name counterpart. On average, the cost of a one-month supply of Mesalamine is $1,225.13. If you use a Mesalamine coupon by SingleCare, you can reduce your Mesalamine cost to as little as $79.32 per 120, 1.2gm tablet delayed releases. Participating pharmacies include CVS, Walmart, Kroger, Walgreens, and more. You can ask your local pharmacy to save your SingleCare Mesalamine discount card for future refills and pharmaceutical purchases too.
Typically, your Mesalamine prescription may cost about $1,225.13 for 120, 1.2gm tablet delayed releases with no insurance. SingleCare, however, allows patients to have an alternative to insurance. By using the free savings card at any of the participating pharmacies, patients can save as much as 80% on the price of their prescriptions whether they have insurance or not. With SingleCare, you can pay a discounted cash price of $79.32 by using the Mesalamine coupons below.
Mesalamine coverage varies by insurance plan, but you can save money by using SingleCare. With SingleCare's Mesalamine coupons, your out-of-pocket cost for Mesalamine can be as little as $79.32 for 120, 1.2gm tablet delayed releases. Note: You do not use SingleCare savings with insurance but instead of insurance. SingleCare copays are sometimes cheaper than insurance coverage.
Generally, Medicare insurance plans do not offer copay assistance for Mesalamine. You can, however, get a discount on your Mesalamine prescription by using SingleCare. SingleCare's prescription discount card can lower your cost of Mesalamine to $79.32 for each prescription refill 120, 1.2gm tablet delayed releases. You can use these discounts at many local pharmacies like Walmart, Kroger, and Walgreens among others.
Mesalamine is a generic drug manufactured by Zydus Pharmaceuticals, Inc. Other drug companies, such as Mylan Pharmaceuticals Inc. and Teva, make generic versions of Mesalamine as well. Brand names for Mesalamine include Lialda (manufactured by Cosmo Pharmaceuticals N.V.), Delzicol (manufactured by Allergan, Inc.), and Canasa (manufactured by Allergan, Inc.). Search for these drugs on SingleCare to find the coupon for the most savings. The retail price may vary depending on which version your healthcare provider prescribes.
Mesalamine is FDA-approved to treat the symptoms of bowel disease called ulcerative colitis. These symptoms include diarrhea, rectal bleeding, inflammation, tissue damage, and stomach pain. Mesalamine belongs to a class of drugs called aminosalicylate anti-inflammatory agents. It can also be used to help prevent symptoms of ulcerative colitis from recurring. Mesalamine works by reducing the swelling and inflammation of cells in the colon.
Mesalamine is available in different brands, each delivering different doses of medication. Some Mesalamine formulations are used by adults only, and some can also be used by children five years and older. The pill should be taken whole (and not split, chewed, or crushed) to allow the drug to be properly released into the colon.
Before using Mesalamine, you should let your doctor know if you have ever had any of the following: a blockage in your stomach or intestines (such as pyloric stenosis), a skin condition such as eczema, liver disease, or kidney disease.
The most common side effects of Mesalamine include headache, flatulence, and abdominal pain or discomfort. Other side effects may include nausea or vomiting, bloody stool, diarrhea, rectal bleeding, blurred vision, constipation, dizziness, fever, and a full or bloated feeling.
This is not a complete list of side effects. You can contact your healthcare provider for more information on other possible side effects or allergic reactions. It is recommended that you seek medical advice before using Mesalamine to ensure that it may be right for you.
Note: Mesalamine should not be used by persons who are allergic to aspirin, sulfasalazine, or salicylates (such as Pepto-Bismol).
After receiving her doctorate from the University of Pittsburgh School of Pharmacy, Karen Berger, Pharm.D., has worked in both chain and independent community pharmacies. She currently works at an independent pharmacy in New Jersey. Dr. Berger enjoys helping patients understand medical conditions and medications—both in person as a pharmacist, and online as a medical writer and reviewer.
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Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
Blog articles are not medical advice. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911.
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© 2025 SingleCare Administrators. All rights reserved