Sulfasalazine Coupons & Prices

Azulfidine En-Tabs

Sulfasalazine is an FDA approved generic anti-inflammatory drug used to treat ulcerative colitis–a disease in which the inner lining of the colon becomes inflamed and develops ulcers and sores–as well as rheumatoid arthritis. It works by reducing swelling and so relieves many of the symptoms caused by these conditions. Sulfasalazine is only available with a prescription. On average, the retail price of Sulfasalazine is $78.23 for 120, 500mg tablets, but only costs $19.88 for 120, 500mg tablets with a SingleCare Sulfasalazine coupon. Many local pharmacies–CVS pharmacy, Kroger, Walmart, Walgreens, and others–accept SingleCare prescription discounts.

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Sulfasalazine coupon at Publix Pharmacy
$22.88
$ 19.88
$3 off with signupwith signup

Show this free card to your pharmacist.

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Sulfasalazine coupon at Walmart Neighborhood Market Pharmacy
$28.46
$ 25.46
$3 off with signupwith signup

Save an extra $3 on any eligible prescription! Sign up for free

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Sulfasalazine coupon at Walmart Pharmacy
$28.46
$ 25.46
$3 off with signupwith signup
Sulfasalazine coupon at Kroger Pharmacy
$28.81
$ 25.81
$3 off with signupwith signup
Sulfasalazine coupon at Harris Teeter Pharmacy
$28.81
$ 25.81
$3 off with signupwith signup
Sulfasalazine coupon at Food Lion Pharmacy
$ 32.60
$ 32.99
$45.00
$ 42.00
$3 off with signupwith signup
$53.10
$ 50.10
$3 off with signupwith signup

About SingleCare Pricing

SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.

Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.

Prices updated: 12/05/2025

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About Sulfasalazine

Sulfasalazine is an FDA approved generic anti-inflammatory drug used to treat ulcerative colitis–a disease in which the inner lining of the colon becomes inflamed and develops ulcers and sores–as well as rheumatoid arthritis. It works by reducing swelling and so relieves many of the symptoms caused by these conditions. Sulfasalazine is only available with a prescription. On average, the retail price of Sulfasalazine is $78.23 for 120, 500mg tablets, but only costs $19.88 for 120, 500mg tablets with a SingleCare Sulfasalazine coupon. Many local pharmacies–CVS pharmacy, Kroger, Walmart, Walgreens, and others–accept SingleCare prescription discounts.

Sulfasalazine Price History & Information

Price History for Sulfasalazine

120 count, tablet, 500mg

Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.

Average 1-Month Prices for Sulfasalazine

120 count, tablet, 500mg
PharmacySulfasalazine Retail PriceSulfasalazine SingleCare Price
CVS Pharmacy$48.00$31.20
Walmart$39.60$25.20
Walgreens$56.40$16.80
Kroger Pharmacy$32.40$28.80

These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.

About Sulfasalazine

Sulfasalazine is an FDA approved generic anti-inflammatory drug used to treat ulcerative colitis–a disease in which the inner lining of the colon becomes inflamed and develops ulcers and sores–as well as rheumatoid arthritis. It works by reducing swelling and so relieves many of the symptoms caused by these conditions. Sulfasalazine is only available with a prescription. On average, the retail price of Sulfasalazine is $78.23 for 120, 500mg tablets, but only costs $19.88 for 120, 500mg tablets with a SingleCare Sulfasalazine coupon. Many local pharmacies–CVS pharmacy, Kroger, Walmart, Walgreens, and others–accept SingleCare prescription discounts.

Sulfasalazine FAQs

Medically reviewed by Karen BergerPharm.D.
Licensed Pharmacist

How much does Sulfasalazine cost without insurance?

A prescription of 120, 500mg tablets will cost around $78.23 for uninsured customers, but dosages and quantities may vary. With a SingleCare Sulfasalazine coupon, you will pay a reduced cash price of $19.88 for 120, 500mg tablets of {{drug}.

How much does Sulfasalazine cost with insurance?

Your copay for Sulfasalazine with insurance will vary depending on your plan and the dosage required. Ask your pharmacist to compare the pricing of your insurance copay to SingleCare. You may find your free discount card saves you money–with SingleCare, Sulfasalazine only costs $19.88 for 120, 500mg tablets.

Does Medicare cover Sulfasalazine and how much does it cost?

As a common generic prescription drug, Sulfasalazine is almost always covered for Medicare-eligible patients under Medicare Part D and Medicare Advantage. However, your copay cost varies according to your plan, so check with your pharmacist. You will always save money with SingleCare Sulfasalazine coupons. The price of Sulfasalazine with a SingleCare discount card is only $19.88 for 120, 500mg tablets.

Is there a generic of Sulfasalazine?

Sulfasalazine is a generic drug and is the active ingredient in the brand-name prescription drugs Azulfidine and Sulfazine. Several different pharmaceutical companies manufacture generic Sulfasalazine. Before you pay for your Sulfasalazine prescription, find free coupons for generic Sulfasalazine or its brand-name equivalent on our website or app.

What is Sulfasalazine?

Sulfasalazine is a generic anti-inflammatory prescription drug primarily used to treat symptoms caused by ulcerative colitis. Ulcerative colitis causes swelling and sores along the inner lining of the colon and rectum. Sulfasalazine works by reducing the swelling caused by ulcerative colitis and so reduces the symptoms–fever, diarrhea, bleeding, and pain–caused by the disease.

Extended-release Sulfasalazine is also sometimes used, along with rest and other drugs, for rheumatoid arthritis when other prescription drugs have failed.

Sulfasalazine is taken in single or extended-release doses. Your doctor will determine the correct dosage and prescription strength for your condition.

What are the side effects of Sulfasalazine?

Although not a complete list, common side effects of Sulfasalazine include loss of appetite, headache, indigestion, stomach pain, nausea, vomiting, headache, dizziness, and lowered sperm count. Mood changes are less common and include insomnia and depression.

If you have symptoms of a rare but serious allergic reaction, such as hives, difficulty breathing, or swelling of the lips, face, or tongue, seek emergency medical help right away. Stevens-Johnson syndrome is a rare but life-threatening skin reaction. If you develop skin rashes or lesions, get medical help immediately. Consult your doctor or healthcare professional for medical advice, drug information, and drug interactions. 

Medically reviewed by Karen BergerPharm.D.
Licensed Pharmacist

After receiving her doctorate from the University of Pittsburgh School of Pharmacy, Karen Berger, Pharm.D., has worked in both chain and independent community pharmacies. She currently works at an independent pharmacy in New Jersey. Dr. Berger enjoys helping patients understand medical conditions and medications—both in person as a pharmacist, and online as a medical writer and reviewer.

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Where are Sulfasalazine coupons from SingleCare accepted?

SingleCare is accepted at most national pharmacies and grocers, including the following:

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