Sulfasalazine is an FDA approved generic anti-inflammatory drug used to treat ulcerative colitis–a disease in which the inner lining of the colon becomes inflamed and develops ulcers and sores–as well as rheumatoid arthritis. It works by reducing swelling and so relieves many of the symptoms caused by these conditions. Sulfasalazine is only available with a prescription. On average, the retail price of Sulfasalazine is $78.23 for 120, 500mg tablets, but only costs $19.88 for 120, 500mg tablets with a SingleCare Sulfasalazine coupon. Many local pharmacies–CVS pharmacy, Kroger, Walmart, Walgreens, and others–accept SingleCare prescription discounts.
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SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
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Prices updated: 12/05/2025
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Sulfasalazine is an FDA approved generic anti-inflammatory drug used to treat ulcerative colitis–a disease in which the inner lining of the colon becomes inflamed and develops ulcers and sores–as well as rheumatoid arthritis. It works by reducing swelling and so relieves many of the symptoms caused by these conditions. Sulfasalazine is only available with a prescription. On average, the retail price of Sulfasalazine is $78.23 for 120, 500mg tablets, but only costs $19.88 for 120, 500mg tablets with a SingleCare Sulfasalazine coupon. Many local pharmacies–CVS pharmacy, Kroger, Walmart, Walgreens, and others–accept SingleCare prescription discounts.
Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.
| Pharmacy | Sulfasalazine Retail Price | Sulfasalazine SingleCare Price |
|---|---|---|
| CVS Pharmacy | $48.00 | $31.20 |
| Walmart | $39.60 | $25.20 |
| Walgreens | $56.40 | $16.80 |
| Kroger Pharmacy | $32.40 | $28.80 |
These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.
Sulfasalazine is an FDA approved generic anti-inflammatory drug used to treat ulcerative colitis–a disease in which the inner lining of the colon becomes inflamed and develops ulcers and sores–as well as rheumatoid arthritis. It works by reducing swelling and so relieves many of the symptoms caused by these conditions. Sulfasalazine is only available with a prescription. On average, the retail price of Sulfasalazine is $78.23 for 120, 500mg tablets, but only costs $19.88 for 120, 500mg tablets with a SingleCare Sulfasalazine coupon. Many local pharmacies–CVS pharmacy, Kroger, Walmart, Walgreens, and others–accept SingleCare prescription discounts.
A prescription of 120, 500mg tablets will cost around $78.23 for uninsured customers, but dosages and quantities may vary. With a SingleCare Sulfasalazine coupon, you will pay a reduced cash price of $19.88 for 120, 500mg tablets of {{drug}.
Your copay for Sulfasalazine with insurance will vary depending on your plan and the dosage required. Ask your pharmacist to compare the pricing of your insurance copay to SingleCare. You may find your free discount card saves you money–with SingleCare, Sulfasalazine only costs $19.88 for 120, 500mg tablets.
As a common generic prescription drug, Sulfasalazine is almost always covered for Medicare-eligible patients under Medicare Part D and Medicare Advantage. However, your copay cost varies according to your plan, so check with your pharmacist. You will always save money with SingleCare Sulfasalazine coupons. The price of Sulfasalazine with a SingleCare discount card is only $19.88 for 120, 500mg tablets.
Sulfasalazine is a generic drug and is the active ingredient in the brand-name prescription drugs Azulfidine and Sulfazine. Several different pharmaceutical companies manufacture generic Sulfasalazine. Before you pay for your Sulfasalazine prescription, find free coupons for generic Sulfasalazine or its brand-name equivalent on our website or app.
Sulfasalazine is a generic anti-inflammatory prescription drug primarily used to treat symptoms caused by ulcerative colitis. Ulcerative colitis causes swelling and sores along the inner lining of the colon and rectum. Sulfasalazine works by reducing the swelling caused by ulcerative colitis and so reduces the symptoms–fever, diarrhea, bleeding, and pain–caused by the disease.
Extended-release Sulfasalazine is also sometimes used, along with rest and other drugs, for rheumatoid arthritis when other prescription drugs have failed.
Sulfasalazine is taken in single or extended-release doses. Your doctor will determine the correct dosage and prescription strength for your condition.
Although not a complete list, common side effects of Sulfasalazine include loss of appetite, headache, indigestion, stomach pain, nausea, vomiting, headache, dizziness, and lowered sperm count. Mood changes are less common and include insomnia and depression.
If you have symptoms of a rare but serious allergic reaction, such as hives, difficulty breathing, or swelling of the lips, face, or tongue, seek emergency medical help right away. Stevens-Johnson syndrome is a rare but life-threatening skin reaction. If you develop skin rashes or lesions, get medical help immediately. Consult your doctor or healthcare professional for medical advice, drug information, and drug interactions.
After receiving her doctorate from the University of Pittsburgh School of Pharmacy, Karen Berger, Pharm.D., has worked in both chain and independent community pharmacies. She currently works at an independent pharmacy in New Jersey. Dr. Berger enjoys helping patients understand medical conditions and medications—both in person as a pharmacist, and online as a medical writer and reviewer.
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Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
Blog articles are not medical advice. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911.
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© 2025 SingleCare Administrators. All rights reserved