Atgam is a prescription medication used to prevent the body from rejecting kidney transplants and to treat certain types of severe aplastic anemia. This brand-name drug contains an immune globulin derived from horse (equine) serum. Atgam is typically administered as an intravenous (IV) infusion by a healthcare provider in a hospital or clinical setting. It is not available at typical retail pharmacies, and a SingleCare discount card may not be applicable to save on the cost of the medication.
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Prices updated: 12/05/2025
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Atgam is a prescription medication used to prevent the body from rejecting kidney transplants and to treat certain types of severe aplastic anemia. This brand-name drug contains an immune globulin derived from horse (equine) serum. Atgam is typically administered as an intravenous (IV) infusion by a healthcare provider in a hospital or clinical setting. It is not available at typical retail pharmacies, and a SingleCare discount card may not be applicable to save on the cost of the medication.
Atgam is a prescription medication used to prevent the body from rejecting kidney transplants and to treat certain types of severe aplastic anemia. This brand-name drug contains an immune globulin derived from horse (equine) serum. Atgam is typically administered as an intravenous (IV) infusion by a healthcare provider in a hospital or clinical setting. It is not available at typical retail pharmacies, and a SingleCare discount card may not be applicable to save on the cost of the medication.
The cost of Atgam without insurance can vary depending on several factors, including the dose you need and the healthcare facility where it’s given. The cost is typically part of your hospital or treatment bill since it is not a medication you pick up at a local pharmacy. Prices can range widely, often running into the thousands of dollars for a full course of treatment.
The cost of Atgam with insurance depends on your specific insurance plan. Many health insurance plans may cover the cost of Atgam when administered as part of a hospital or clinical treatment. However, you might still be responsible for a portion of the cost, such as a copay or coinsurance amount. Check with your insurance provider to determine your out-of-pocket costs for this treatment.
Medicare may cover the cost of Atgam under Part B, as this medication is typically administered in a healthcare setting, such as a hospital or clinic. Coverage and costs can vary based on your specific Medicare plan and coverage stage. It’s a good idea to consult your healthcare provider and Medicare plan for more information about coverage options and potential out-of-pocket costs.
Currently, Atgam is not available in a generic or biosimilar form. The earliest a generic or biosimilar may become available is around 2033. Atgam is a unique medicine made from horse (equine) immune globulin, which means that any substitute would need to go through a rigorous clinical trial process before becoming available.
Atgam is a prescription medication that’s used in two critical medical situations: to prevent organ transplant rejection and to treat severe aplastic anemia, a condition where the bone marrow fails to produce enough blood cells. Atgam works by suppressing the immune system, specifically targeting T-lymphocytes, which are the white blood cells involved in the body’s immune response. It is administered as an IV injection.
Common side effects of Atgam include:
Fever
Chills
Rash
Muscle or joint pain
These side effects are typically mild, but they may cause discomfort. Your healthcare provider will monitor you closely during treatment to manage any symptoms that arise.
More serious side effects can occur, although they are less common. These may include:
Severe allergic reactions (anaphylaxis)
Low blood cell counts (thrombocytopenia, leukopenia)
Increased risk of infections
Tell your healthcare provider immediately if you experience any severe side effects. They can provide the best medical advice and make any necessary changes to your treatment.
Atgam and thymoglobulin are both immune globulin products used to suppress the immune system, but they are not the same. Atgam is derived from horse (equine) serum, while thymoglobulin is derived from rabbit serum. Each medicine has a different makeup and may work differently for each person. Your healthcare provider will decide which is best for you based on your health and how you have responded to treatments.
Atgam is usually given in a hospital or clinic because it needs close monitoring. It is given through an IV, which requires special equipment and medical staff to watch for side effects or reactions. Therefore, Atgam is not typically given in an outpatient setting. People who receive this treatment usually need to stay in the hospital while the drug is given and for some time after to make sure they are okay.
Gerardo Sison, Pharm.D., graduated from the University of Florida. He has worked in both community and hospital settings, providing drug information and medication therapy management services. As a medical writer, he hopes to educate and empower patients to better manage their health and navigate their treatment plans.
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Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
Blog articles are not medical advice. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911.
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© 2025 SingleCare Administrators. All rights reserved