Wellbutrin XL (bupropion XL) is a brand-name antidepressant prescription medication that is taken to treat major depressive disorder (MDD) or depression. It can also be used to prevent seasonal affective disorder. Bupropion hydrochloride extended-release is the active ingredient and generic version of Wellbutrin XL. You can receive prescription savings on Wellbutrin XL or its generic version when you use SingleCare's coupons. If you are purchasing Wellbutrin XL out-of-pocket, the Wellbutrin XL retail price might be about $3,635.96 for 30, 300mg tablet extended release 24 hours. However, Wellbutrin XL coupons from SingleCare can lower your cost to the discounted price of $6.99 for 30, 150mg tablets of generic Wellbutrin XL on your prescription—and on refills, too. You can bring your Wellbutrin XL coupon card to participating pharmacies. On SingleCare's website, you can locate participating pharmacies within your area.
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SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
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Prices updated: 12/05/2025
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Wellbutrin XL (bupropion XL) is a brand-name antidepressant prescription medication that is taken to treat major depressive disorder (MDD) or depression. It can also be used to prevent seasonal affective disorder. Bupropion hydrochloride extended-release is the active ingredient and generic version of Wellbutrin XL. You can receive prescription savings on Wellbutrin XL or its generic version when you use SingleCare's coupons. If you are purchasing Wellbutrin XL out-of-pocket, the Wellbutrin XL retail price might be about $3,635.96 for 30, 300mg tablet extended release 24 hours. However, Wellbutrin XL coupons from SingleCare can lower your cost to the discounted price of $6.99 for 30, 150mg tablets of generic Wellbutrin XL on your prescription—and on refills, too. You can bring your Wellbutrin XL coupon card to participating pharmacies. On SingleCare's website, you can locate participating pharmacies within your area.
Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.
| Pharmacy | Wellbutrin Xl Retail Price | Bupropion Hcl Er (Xl) Retail Price | Bupropion Hcl Er (Xl) SingleCare Price |
|---|---|---|---|
| CVS Pharmacy | - | $108.26 | $36.20 |
| Walmart | - | $27.25 | $15.50 |
| Walgreens | - | $83.14 | $49.84 |
| Kroger Pharmacy | $3821.10 | $78.74 | $10.11 |
| Albertsons Pharmacy | - | $106.57 | $19.50 |
These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.
Wellbutrin XL (bupropion XL) is a brand-name antidepressant prescription medication that is taken to treat major depressive disorder (MDD) or depression. It can also be used to prevent seasonal affective disorder. Bupropion hydrochloride extended-release is the active ingredient and generic version of Wellbutrin XL. You can receive prescription savings on Wellbutrin XL or its generic version when you use SingleCare's coupons. If you are purchasing Wellbutrin XL out-of-pocket, the Wellbutrin XL retail price might be about $3,635.96 for 30, 300mg tablet extended release 24 hours. However, Wellbutrin XL coupons from SingleCare can lower your cost to the discounted price of $6.99 for 30, 150mg tablets of generic Wellbutrin XL on your prescription—and on refills, too. You can bring your Wellbutrin XL coupon card to participating pharmacies. On SingleCare's website, you can locate participating pharmacies within your area.
If you are purchasing Wellbutrin XL without insurance coverage, you can expect to pay about $3,635.96 for 30, 300mg tablet extended release 24 hours. However, you can reduce the cost of Wellbutrin XL by using a Wellbutrin XL coupon. Your Wellbutrin XL coupon can lower your price to $6.99 for 30, 150mg tablets of generic Wellbutrin XL. SingleCare's savings card can be used at your local pharmacy that participates in our program. Anyone can use SingleCare in the US—there are no eligibility criteria other than a valid prescription. Access our website or mobile app, and start saving today!
Your health insurance company will determine the average copay for Wellbutrin XL. Insurance companies may charge a higher price for the brand-name, or require you to use a generic to cover this medication. SingleCare may be cheaper than insurance. When you visit a participating pharmacy, you can ask the pharmacist to process your discount card to compare prescription prices between using either insurance or SingleCare. You can always contact your insurance provider for the most recent pricing information.
Medicare Part D and Medicare Advantage plans do not typically cover Wellbutrin XL as a brand name drug, but they do cover generic. You can use coupons from the SingleCare discount program to save money. Wellbutrin XL coupons can be used at select participating pharmacies. When you use your Wellbutrin XL coupon card, you can pay about $6.99 for 30, 150mg tablets of generic Wellbutrin XL.
Bupropion extended-release is the FDA-approved, generic version of Wellbutrin XL.
Wellbutrin XL is a prescription drug that is taken to treat major depressive disorder (depression) or seasonal affective disorder. Wellbutrin XL is available as an extended-release tablet. (There is also an immediate-release form of bupropion called Wellbutrin and a sustained-release form of bupropion called Wellbutrin SR.)
Major depressive disorder (also referred to as depression) causes patients to experience persistent sadness and a loss of interest.
Seasonal affective disorder can be triggered by seasonal changes. When there is reduced sunlight, your body can experience a decrease in serotonin and melatonin levels. Fall or winter conditions (less sunlight) can increase your risk of having seasonal depression since sunlight helps your brain to release serotonin.
The exact way Wellbutrin XL works is not exactly known but is thought to be by balancing norepinephrine and dopamine in the brain. For patients diagnosed with seasonal depression, Wellbutrin XL is recommended to be taken in the autumn before symptoms develop. Wellbutrin XL should be taken throughout winter, and slowly tapered in the spring. When you stop taking Wellbutrin XL, whether for MDD or seasonal affective disorder, your healthcare provider will advise you on a tapering schedule. Wellbutrin XL should never be stopped abruptly, because withdrawal symptoms could occur.
With any antidepressant, there may be an increased risk of suicidal thoughts and behaviors. If you experience any suicidal thoughts while taking Wellbutrin XL, you should tell your healthcare provider immediately. Family members and caregivers should also be alert to any changes in your mood and behavior and get medical help if changes occur.
Because Wellbutrin XL is extended-release, the tablet should be swallowed whole—do not chew or crush. Wellbutrin XL is usually taken once daily, in the morning.
You should talk to your healthcare provider before using Wellbutrin XL. Ask your healthcare provider for medical advice to learn if Wellbutrin XL is right for you. Tell your healthcare provider about all the medications you take, including prescription drugs, OTC medicines, and vitamins or supplements, so he or she can make sure that Wellbutrin XL is safe to take with your other medicines.
Some common side effects of Wellbutrin XL are headache, dry mouth, nausea, constipation, diarrhea, agitation, dizziness, weight loss, insomnia, abnormal dreams, and others.
Severe allergic reactions are rare, but if you experience any of the following symptoms: hives, difficulty breathing, swelling of the face, lips, tongue, or throat—you should seek emergency medical help at a nearby hospital.
Other side effects may occur, including serious side effects. Consult your healthcare provider for additional information, questions, and medical advice regarding adverse effects.
Although Wellbutrin XL alone is not FDA-approved for weight loss, the active ingredient, bupropion, tends to help people lose weight, especially when combined with diet and exercise. In fact, bupropion is one ingredient in the weight-loss medication called Contrave. People who take Wellbutrin XL may see a weight loss of anywhere from two to 10%, although weight changes may vary based on many factors, including lifestyle changes. However, it’s also important to note that some people who took Wellbutrin XL gained weight in clinical studies. If weight loss is a consideration, consult your healthcare professional for medical advice.
If you find that Wellbutrin XL is not the right drug for you, there are other alternatives. In fact, there are several categories of antidepressants. For example, an SSRI antidepressant such as Lexapro (escitalopram), or an SNRI antidepressant such as Effexor (venlafaxine) may be a better option for some individuals. Because so many factors go into selecting the appropriate medication, it’s important to discuss medication selection with your healthcare provider, who can advise you on the medication that would be best for you.
After receiving her doctorate from the University of Pittsburgh School of Pharmacy, Karen Berger, Pharm.D., has worked in both chain and independent community pharmacies. She currently works at an independent pharmacy in New Jersey. Dr. Berger enjoys helping patients understand medical conditions and medications—both in person as a pharmacist, and online as a medical writer and reviewer.
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Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
Blog articles are not medical advice. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911.
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© 2025 SingleCare Administrators. All rights reserved