What is Clenpiq: Uses, Warnings & Interactions

Your doctor will tell you how much medicine to use. Do not use more than directed.

Split-dose dosing:

• Take the first dose the evening before your colonoscopy.

• Take the second dose the next day, in the morning or at least 5 hours before your colonoscopy.

• If you have severe bloating, distension, or stomach pain after taking the first dose, you may need to wait until your symptoms improve before taking the second dose.

To use Clenpiq:

• Clenpiq is ready to drink. One bottle is equal to one dose.

• You will need two doses of this medicine. Drink all of this medicine straight from the bottle.

• Clenpiq is a clear solution that may contain visible particles. 

Drink at least five 8-oz cups of clear liquids after the first dose of Clenpiq and at least four 8-oz cups of clear liquids after the second dose. 

It’s recommended to drink a variety of clear liquids. Examples include balanced electrolyte solutions, black coffee or tea, plain jello, clear broth, clear juices without pulp, ginger ale and other sodas, and frozen juice bars. Do not drink anything colored red or purple. 

Do not consume solid food, dairy products, or alcohol on the day before the colonoscopy and until after the colonoscopy is finished.

Be sure to stop all consumption of liquids at least 2 hours before your procedure.

This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Do not refrigerate or freeze Clenpiq.

Contact your doctor if you miss a dose of Clenpiq. Depending on the timing of your missed dose, they may recommend that you take the dose. Or they may have to reschedule your procedure.

This medicine is not right for everyone. Do not use it if you’ve had an allergic reaction to citric acid, magnesium oxide, sodium picosulfate, or any of the other ingredients in the drug.

People who have severe kidney problems and stomach or bowel problems (including blockage, perforation, toxic colitis or toxic megacolon, or problems emptying food or liquids from the stomach) also should not take Clenpiq.

Tell your doctor if you have any of the following conditions:

• Kidney disease

• Heart rhythm problems

• Heart failure

• Recent heart attack

• Trouble swallowing

• Ulcerative colitis

• Inflammatory bowel disease

• History of seizures

This medicine may cause the following problems:

• Heart rhythm problems (including arrhythmia)

• Seizures

• Kidney problems

• Stomach or bowel problems (including ulcers, blockages, and holes in the wall of your gut)

This medicine may cause dehydration. Drink extra liquids before, during, and after you take this medicine.

Keep all medicine out of the reach of children. Never share your medicine with anyone.

Do not take other laxatives while you are taking this medicine, and do not take any oral medicine within one hour before you take it.

Some medicines can affect how this medicine works. Tell your doctor if you are taking any of the following:

• Blood pressure medicine

• Diuretic (water pill)

• Medicine for heart rhythm problems

• Medicine to treat depression or mental illness

• Medicine for kidney problems

• NSAID pain or arthritis medicine (including aspirin, diclofenac, ibuprofen, naproxen)

• Steroid medicine (including hydrocortisone, methylprednisolone, prednisolone, prednisone)

Take chlorpromazine, digoxin, penicillamine, iron, tetracycline, or fluoroquinolone antibiotics at least 2 hours before or 6 hours after you take this medicine.

Do not drink alcohol while you are using this medicine.