Cortef is a brand-name prescription drug that is prescribed to reduce swelling across a broad spectrum of diseases and conditions: allergies, asthma, drug reactions, gastrointestinal conditions, eye conditions, arthritis, lupus, skin conditions, and certain cancers. Because the adrenal gland produces a hormone nearly identical to the active ingredient in Cortef, hydrocortisone, treatment with Cortef or generic hydrocortisone is the treatment of choice for adrenal gland problems. Hydrocortisone belongs to a family of drugs called corticosteroids. These drugs reduce swelling by blocking the production of inflammatory chemicals produced by the immune system. The prescription price for Cortef is $210.55. A SingleCare Cortef coupon, however, reduces that cost significantly to $24.50. Many local pharmacies across the country —CVS, Longs Drugs, Walgreens, and many more—participate in the SingleCare savings program.
Edit your dosage
30 tablet, 5mgEdit
You have 0.00 in available bonus savings. Bonus savings will be automatically applied to your next eligible prescription fill.
Show this free card to your pharmacist.
SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.
Prices updated: 04/17/2026
Cortef is a brand-name prescription drug that is prescribed to reduce swelling across a broad spectrum of diseases and conditions: allergies, asthma, drug reactions, gastrointestinal conditions, eye conditions, arthritis, lupus, skin conditions, and certain cancers. Because the adrenal gland produces a hormone nearly identical to the active ingredient in Cortef, hydrocortisone, treatment with Cortef or generic hydrocortisone is the treatment of choice for adrenal gland problems. Hydrocortisone belongs to a family of drugs called corticosteroids. These drugs reduce swelling by blocking the production of inflammatory chemicals produced by the immune system. The prescription price for Cortef is $210.55. A SingleCare Cortef coupon, however, reduces that cost significantly to $24.50. Many local pharmacies across the country —CVS, Longs Drugs, Walgreens, and many more—participate in the SingleCare savings program.
Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.
| Pharmacy | Hydrocortisone Retail Price | Hydrocortisone SingleCare Price |
|---|---|---|
| CVS Pharmacy | $49.95 | $32.40 |
| Walmart | $54.00 | $54.00 |
| Walgreens | $29.47 | $29.47 |
| Kroger Pharmacy | $45.90 | $31.50 |
| Albertsons Pharmacy | $46.80 | $36.90 |
These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.
Cortef is a brand-name prescription drug that is prescribed to reduce swelling across a broad spectrum of diseases and conditions: allergies, asthma, drug reactions, gastrointestinal conditions, eye conditions, arthritis, lupus, skin conditions, and certain cancers. Because the adrenal gland produces a hormone nearly identical to the active ingredient in Cortef, hydrocortisone, treatment with Cortef or generic hydrocortisone is the treatment of choice for adrenal gland problems. Hydrocortisone belongs to a family of drugs called corticosteroids. These drugs reduce swelling by blocking the production of inflammatory chemicals produced by the immune system. The prescription price for Cortef is $210.55. A SingleCare Cortef coupon, however, reduces that cost significantly to $24.50. Many local pharmacies across the country —CVS, Longs Drugs, Walgreens, and many more—participate in the SingleCare savings program.
Cortef costs $210.55 at full price. A SingleCare Cortef coupon, however, lowers the price of Cortef to $24.50 per 90, 10mg tablets. At SingleCare participating pharmacies, you can routinely enjoy savings of as much as 80% on all your prescription drug needs. Just bring your SingleCare discount card along with your prescription.
Insurance copays for Cortef, like any other prescription drug, depend on your insurance plan and the dosage prescribed. Talk to your pharmacist to see if a SingleCare Cortef coupon may cost you less than paying for your prescription using insurance. With SingleCare, Cortef costs $24.50, which might beat your insurance copay.
Cortef is usually not covered by Medicare Advantage or Medicare Part D prescription drug plans, but generic hydrocortisone tablets are. Patients without Cortef coverage should consider filling their Cortef prescription with a SingleCare Cortef coupon. You pay $24.50 at participating pharmacies located right in your neighborhood, like CVS or Target, among others.
Cortef is a brand-name prescription drug with hydrocortisone and is administered as a tablet. Generic Cortef is available from manufacturers such as Breckenridge, Hikma, and Vintage, among others. And before you overpay for your Cortef prescription, search for hydrocortisone or Cortef coupons on the SingleCare website or app.
Cortef is a brand-name prescription drug that is prescribed to reduce swelling across a broad spectrum of diseases and conditions. These include allergies (allergic reactions, skin reactions, asthma, sinus problems, and drug reactions), arthritis (rheumatoid arthritis, juvenile idiopathic arthritis, osteoarthritis, and other forms of rheumatism or arthritis), skin conditions (dermatitis, scaling dermatitis, psoriasis), gastrointestinal conditions (ulcerative colitis, enteritis, and others), blood conditions (anemia, low platelet counts, and others), cancers (leukemias, lymphomas), respiratory diseases and conditions (tuberculosis, pneumonitis, and others), eye problems (conjunctivitis, dry eye, herpes, and others), and other diseases and conditions.
Because the adrenal gland produces a hormone nearly identical to the active ingredient in Cortef, hydrocortisone, treatment with Cortef or generic hydrocortisone is the treatment of choice for hormone replacement when the adrenal gland does not produce enough hormones.
Cortef is a corticosteroid, a family of drugs that reduces swelling by blocking the immune system's ability to release chemicals that cause swelling. Cortef is taken as a tablet. The dosage will depend on the underlying condition being treated.
The most common side effects of Cortef include, but are not limited to, acne, dry skin, thinning skin, bruising, headache, dizziness, vertigo, nausea, indigestion, stomach pain, bloating, and muscle weakness. Serious but less common side effects include high blood pressure, convulsions, osteoporosis (bone loss), and glaucoma (elevated fluid pressure in the eye). The active ingredient in Cortef, hydrocortisone, may cause mood swings. Allergic reactions are rare, but discontinue Cortef at any sign of an allergic reaction, such as rash, hives, or trouble breathing.
This is not a complete list of side effects. Consult with your doctor or pharmacist if you have concerns or questions about possible side effects of Cortef.
SingleCare is accepted at most national pharmacies and grocers, including the following:
Health education, drug info, wellness & more
SingleCare is a prescription discount service that offers free coupons on thousands of prescription drugs. It can be used whether you have insurance, Medicare, Medicaid, or none of the above, but it cannot be combined with insurance.
SingleCare provides transparent drug pricing, so you can compare discounts at pharmacies near you. Browse singlecare.com to find drug discounts, helpful information about your prescription, and resources to help you make informed health decisions.
Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
Blog articles are not medical advice. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911.
© 2026 SingleCare Administrators. All rights reserved
© 2026 SingleCare Administrators. All rights reserved