What is Depo-Estradiol: Uses, Warnings & Interactions

Injection routeYour doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given as a shot into one of your muscles. You may receive this medicine once a week, once every 2 weeks, or once every 4 weeks.

If you have not had your uterus removed (hysterectomy), you may need to use another hormone medicine together with estradiol. Carefully follow your doctor's instructions about all medicines you are using.

Injection routeA nurse or other health provider will give you this medicine.

Injection routeYou may be taught how to give your medicine at home. Make sure you understand all instructions before giving yourself an injection. Do not use more medicine or use it more often than your doctor tells you to.

Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

Injection routeUse a new needle and syringe each time you inject your medicine.

If you have not had your uterus removed (hysterectomy), you may need to use another hormone medicine together with estradiol. Carefully follow your doctor's instructions about all medicines you are using.

Injection routeA nurse or other health provider will give you this medicine.

Injection routeUse a new needle and syringe each time you inject your medicine.

Injection routeYou may be taught how to give your medicine at home. Make sure you understand all instructions before giving yourself an injection. Do not use more medicine or use it more often than your doctor tells you to.

Injection routeYour doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given as a shot into one of your muscles. You may receive this medicine once a week, once every 2 weeks, or once every 4 weeks.

Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

Injection routeCall your doctor or pharmacist for instructions.

Injection routeThrow away used needles in a hard, closed container that the needles cannot poke through. Keep this container away from children and pets.

Injection routeAsk your pharmacist, doctor, or health caregiver about the best way to dispose of any leftover medicine, containers, and other supplies. Throw away old medicine after the expiration date has passed.

Keep all medicine out of the reach of children. Never share your medicine with anyone.

You should not use this medicine if you have had an allergic reaction to hormone medicines. Do not use this medicine if you are pregnant, or if you have abnormal vaginal bleeding that has not been checked by a doctor. You should not use this medicine if you have a history of cancer of the breast, ovary, or uterus. Do not use if you have liver disease or a history of heart attack, stroke, or blood clots.

It is unlikely that you will become pregnant while you are going through menopause. But, you should know that using this medicine while you are pregnant could harm your unborn baby. If you think you have become pregnant while using the medicine, tell your doctor right away. If you have recently had an infant, tell your doctor if you are breast feeding.

Make sure your doctor knows if you have asthma, epilepsy, migraine headaches, heart disease, or kidney disease. Also tell your doctor if you have endometriosis, gallbladder disease, liver disease, lupus, porphyria, or an underactive thyroid.

This medicine should not be used to treat or prevent heart disease or stroke. In fact, hormone therapy can increase your risk of certain heart or blood vessel problems. Tell your doctor if you have a history of heart attack, stroke, high blood pressure, congestive heart failure, blood clots, or circulation problems.

Your risk of heart disease or stroke from this medicine is higher if you smoke. Your risk is also increased if you have diabetes or high cholesterol, or if you are overweight. Talk with your doctor about ways to stop smoking. If you have diabetes, keep it under control. Ask your doctor about diet and exercise to control your weight and blood cholesterol level.

This medicine may also increase your risk of other medical problems, including certain types of cancer. Talk with your doctor about how these risks might affect you.

Tell any doctor or dentist who treats you that you are using this medicine. You may need to stop using this medicine several days before you have surgery or medical tests. This medicine may also affect the results of certain medical tests.

Numbness or weakness in your arm or leg, or on one side of your body.

Pain in your lower leg (calf).

Shortness of breath, cold sweat, and bluish-colored skin.

Sudden or severe headache, problems with vision, speech, or walking.

Swelling in your hands, ankles, or feet.

Vaginal bleeding or spotting.

This medicine should not be used to treat or prevent heart disease or stroke. In fact, hormone therapy can increase your risk of certain heart or blood vessel problems. Tell your doctor if you have a history of heart attack, stroke, high blood pressure, congestive heart failure, blood clots, or circulation problems.

This medicine may also increase your risk of other medical problems, including certain types of cancer. Talk with your doctor about how these risks might affect you.

Make sure your doctor knows if you have asthma, epilepsy, migraine headaches, heart disease, or kidney disease. Also tell your doctor if you have endometriosis, gallbladder disease, liver disease, lupus, porphyria, or an underactive thyroid.

It is unlikely that you will become pregnant while you are going through menopause. But, you should know that using this medicine while you are pregnant could harm your unborn baby. If you think you have become pregnant while using the medicine, tell your doctor right away. If you have recently had an infant, tell your doctor if you are breast feeding.

Your risk of heart disease or stroke from this medicine is higher if you smoke. Your risk is also increased if you have diabetes or high cholesterol, or if you are overweight. Talk with your doctor about ways to stop smoking. If you have diabetes, keep it under control. Ask your doctor about diet and exercise to control your weight and blood cholesterol level.

Tell any doctor or dentist who treats you that you are using this medicine. You may need to stop using this medicine several days before you have surgery or medical tests. This medicine may also affect the results of certain medical tests.