Donnatal is a brand-name drug used with other medications to treat digestive issues, such as irritable bowel syndrome, enterocolitis, and duodenal ulcers. The generic version of Donnatal is phenobarbital/hyoscyamine/atropine/scopolamine. It contains a combination of a barbiturate and belladonna alkaloids. It has antispasmodic and sedative effects. The average cost of Donnatal is $477.11 for 30, 16.2mg tablets. You may be able to pay as low as $35.58 for 30, 16.2mg tablets of generic Donnatal with a coupon from SingleCare at participating pharmacies nationwide.
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SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
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Prices updated: 12/05/2025
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Donnatal is a brand-name drug used with other medications to treat digestive issues, such as irritable bowel syndrome, enterocolitis, and duodenal ulcers. The generic version of Donnatal is phenobarbital/hyoscyamine/atropine/scopolamine. It contains a combination of a barbiturate and belladonna alkaloids. It has antispasmodic and sedative effects. The average cost of Donnatal is $477.11 for 30, 16.2mg tablets. You may be able to pay as low as $35.58 for 30, 16.2mg tablets of generic Donnatal with a coupon from SingleCare at participating pharmacies nationwide.
Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.
| Pharmacy | Donnatal Retail Price | Pb-Hyoscy-Atropine-Scopolamine Retail Price | Pb-Hyoscy-Atropine-Scopolamine SingleCare Price |
|---|---|---|---|
| CVS Pharmacy | - | $294.90 | $93.60 |
| Walmart | - | $340.50 | $231.00 |
| Walgreens | $494.10 | $285.00 | $102.00 |
| Kroger Pharmacy | - | - | - |
These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.
Donnatal is a brand-name drug used with other medications to treat digestive issues, such as irritable bowel syndrome, enterocolitis, and duodenal ulcers. The generic version of Donnatal is phenobarbital/hyoscyamine/atropine/scopolamine. It contains a combination of a barbiturate and belladonna alkaloids. It has antispasmodic and sedative effects. The average cost of Donnatal is $477.11 for 30, 16.2mg tablets. You may be able to pay as low as $35.58 for 30, 16.2mg tablets of generic Donnatal with a coupon from SingleCare at participating pharmacies nationwide.
Without insurance, the average retail cost of Donnatal is $477.11 for 30, 16.2mg tablets. The exact cash price of Donnatal will vary depending on the quantity prescribed and where you purchase the drug from. With a SingleCare Donnatal coupon, your price could be reduced to $35.58 for 30, 16.2mg tablets of generic Donnatal.
How much does Donnatal cost with insurance?
The cost of Donnatal with insurance can vary depending on the plan’s coverage. Speak with your insurance plan’s provider or pharmacy to determine your potential copay for Donnatal. Without insurance, you may have to pay the full cash price of the drug. SingleCare may help you to save and cut costs. You could pay $35.58 for 30, 16.2mg tablets of generic Donnatal when you use SingleCare at local pharmacies like CVS or Walgreens.
Medicare insurance plans do not generally offer coverage for Donnatal. Contact your Medicare insurance plan’s provider to determine the cost of Donnatal with Medicare. A SingleCare can help you save on the retail cost of Donnatal if you don’t have Medicare coverage. Take your SingleCare discount card to the checkout line at any participating pharmacy and you could pay $35.58 for 30, 16.2mg tablets of generic Donnatal instead of $477.11 for 30, 16.2mg tablets of Donnatal.
The generic name of Donnatal is phenobarbital-hyoscyamine-atropine-scopolamine. However, a generic version of Donnatal may not be available on the market at this time. Donnatal is a brand-name drug manufactured by Concordia Pharmaceuticals.
Donnatal is a combination drug used to treat irritable bowel syndrome (IBS) and other digestive issues, such as enterocolitis and duodenal ulcers. It contains a barbiturate drug called phenobarbital and belladonna alkaloids called hyoscyamine, atropine, and scopolamine. The combination of these drugs provides anticholinergic, antispasmodic, and sedative effects. Donnatal may help relieve digestive issues by slowing down the natural movements of the gut and relaxing the muscles in the stomach and intestines.
Donnatal comes in two formulations: an immediate-release oral tablet and an elixir. It is typically prescribed in addition to other medications or treatments.
Donnatal should not be used in people who have glaucoma, obstructive uropathy, obstructive disease of the gastrointestinal tract, paralytic ileus, unstable cardiovascular status, severe ulcerative colitis, myasthenia gravis, hiatal hernia with reflux esophagitis, or known hypersensitivity to any of the ingredients in Donnatal.
Donnatal is usually taken three to four times daily. The exact dosage will vary. This medication should only be taken as prescribed by a healthcare provider.
The most common side effects of Donnatal include dry mouth, urinary retention, blurred vision, dilation of the pupils, rapid heartbeat, loss of taste, headache, nervousness, drowsiness, weakness, dizziness, insomnia, nausea, vomiting, impotence, constipation, bloating, and muscle pain.
Serious side effects of Donnatal include fetal harm in pregnant women, intestinal obstruction, severe drowsiness, and physical or psychological dependence on the drug. Severe allergic reactions are also possible while using Donnatal. Seek immediate medical attention if you experience signs or symptoms of an allergic reaction, such as itching, hives, swelling of the face or throat, or difficulty breathing.
This is not a complete list of side effects associated with Donnatal.
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Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
Blog articles are not medical advice. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911.
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© 2025 SingleCare Administrators. All rights reserved