Dramamine is a popular over-the-counter anti-nausea and motion sickness treatment. Its active ingredient, meclizine, is an antihistamine but has other properties, as well. Though healthcare professionals are unsure how it works, it decreases the sensitivity of the inner ear to motion and indirectly affects the brain’s nausea center. To be effective, Dramamine tablets need to be taken at least 30 to 60 minutes before a nausea-inducing event such as travel.
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Dramamine Original, Dramamine Less Drowsy, Dramamine Long-Lasting, Dramamine For Kids
Meclizine HCl
Treats and prevents nausea and vomiting due to motion sickness.
Antiemetic; motion sickness and vertigo antiemetic; antihistamine
Tablet, chewable tablet
By mouth
Dramamine treats and prevents nausea, vomiting, queasiness, and dizziness caused by motion sickness.
Tablet
50 mg (Original)
25 mg (Less Drowsy, Long-Lasting)
Chewable tablet
50 mg (Original)
25 mg (Less Drowsy, For Kids)
For prevention or treatment of nausea due to motion sickness:
In adults and children 12 years of age and older: one to two tablets every four to six hours as needed (Dramamine Original) or one to two tablets once daily (Dramamine Less Drowsy, Dramamine Long-Lasting)
In children 6–11 years of age: one to two Dramamine For Kids chewable tablets or one-half to one Dramamine Original tablet or Dramamine Original chewable tablet every six to eight hours as needed
In children 2–5 years of age: one-half to one Dramamine For Kids chewable tablet or one-half Dramamine Original tablet or Dramamine Original chewable tablet every six to eight hours as needed
Find more information about meclizine dosage, forms, and strengths here.
Dramamine
12 tablets bottle
Dramamine
36 tablets bottle
Dramamine
8 tablets chewable bottle
Read and follow the directions on the label. Do not give more tablets than recommended or give them more often than recommended.
Swallow Dramamine tablets whole.
Do not swallow Dramamine chewable tablets whole. They must be chewed or crushed completely before swallowing.
How to take Dramamine Original or Dramamine For Kids:
Take the first dose at least ½ hour before a nausea-inducing event.
How to take Dramamine Less Drowsy or Dramamine Long-Lasting:
Take the first dose at least one hour before a nausea-inducing event, or take a dose when symptoms start.
Store Dramamine tablets and chewable tablets at room temperature.
If a dose is forgotten, take it when remembered.
Taking a missed dose of Dramamine Original or Dramamine For Kids may not help after symptoms start.
Taking a missed dose will reset the dosing clock. After taking a missed dose:
Do not take or give another dose of Dramamine Original or Dramamine For Kids until several hours have passed.
Do not take another dose of Dramamine Less Drowsy or Dramamine Long-Lasting until the next day.
Do not take extra tablets to make up for a missed dose.
Do not use Dramamine if you have ever had an allergic reaction to meclizine.
Tell any doctor or other healthcare provider who treats you that you are using this medicine.
Before using Dramamine, talk to a doctor if you have:
Any serious lung or breathing disorder such as asthma, chronic bronchitis, or emphysema
Glaucoma
Enlarged prostate
Consult with a healthcare professional if you are pregnant or breastfeeding before taking Dramamine.
Meclizine can make you drowsy. Avoid driving, operating machinery, or engaging in hazardous activities until you know how Dramamine affects you.
To avoid possible drug interactions, tell healthcare professionals who treat you that you are using Dramamine before they prescribe medications.
When using Dramamine, avoid taking other medications that make you sleepy such as sleeping pills, opioids, benzodiazepines, or barbiturates.
Avoid alcohol and cannabis products on days that you take Dramamine doses.
Find more detailed information about meclizine interactions to avoid here.
Serious side effects
Talk to a doctor if you notice any signs or symptoms of a possible serious side effect including:
Blurred vision
Allergic reaction: Itching or hives, skin rash, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
Less serious side effects
Drowsiness
Dry mouth
Headache
Fatigue
Vomiting
Antivert meclizine HCl tablet prescribing information, DailyMed (NIH National Library of Medicine)
Dramamine Long-Lasting, Prestige Consumer Healthcare Inc.
Dramamine Motion Sickness Products, Prestige Consumer Healthcare Inc.
Meclizine drug summary, Prescriber’s Digital Reference (PDR)
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