Fentanyl Coupons & Prices

Fentanyl is a generic opioid pain medication used to help relieve severe ongoing pain from conditions like cancer. It comes in different strengths, such as a skin patch that releases pain medication over time. The average cash price of Fentanyl is around $177.16 for 2, 5 patch 72 hour boxes. SingleCare can lower your cost to $38.37 for 2, 5 patch 72 hour boxes with a Fentanyl coupon. This coupon can be redeemed at participating pharmacies.

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Fentanyl coupon at CVS Pharmacy
$ 38.37

Show this free card to your pharmacist.

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Fentanyl coupon at Kroger Pharmacy
$ 65.50
Fentanyl coupon at Harris Teeter Pharmacy
$ 65.50
Fentanyl coupon at Walgreens Pharmacy
$ 86.88
Fentanyl coupon at Publix Pharmacy
$ 94.66
Fentanyl coupon at Food Lion Pharmacy
$ 113.00

About SingleCare Pricing

SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.

Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.

Prices updated: 12/05/2025

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About Fentanyl

      Controlled Substance

Fentanyl is a generic opioid pain medication used to help relieve severe ongoing pain from conditions like cancer. It comes in different strengths, such as a skin patch that releases pain medication over time. The average cash price of Fentanyl is around $177.16 for 2, 5 patch 72 hour boxes. SingleCare can lower your cost to $38.37 for 2, 5 patch 72 hour boxes with a Fentanyl coupon. This coupon can be redeemed at participating pharmacies.

Fentanyl Price History & Information

Price History for Fentanyl

2 count, box, 5 patch 72 hour

Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.

Average 1-Month Prices for Fentanyl

2 count, box, 5 patch 72 hour
PharmacyFentanyl Retail PriceFentanyl SingleCare Price
CVS Pharmacy$177.00$81.40
Walmart$230.40$230.40
Walgreens$183.86$87.33
Kroger Pharmacy$206.79$165.97
Albertsons Pharmacy$181.00$52.50

These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.

About Fentanyl

Fentanyl is a generic opioid pain medication used to help relieve severe ongoing pain from conditions like cancer. It comes in different strengths, such as a skin patch that releases pain medication over time. The average cash price of Fentanyl is around $177.16 for 2, 5 patch 72 hour boxes. SingleCare can lower your cost to $38.37 for 2, 5 patch 72 hour boxes with a Fentanyl coupon. This coupon can be redeemed at participating pharmacies.

Fentanyl FAQs

Medically reviewed by Anne JacobsonMD, MPH
Board-Certified Family Physician

How much does Fentanyl cost without insurance?

Fentanyl may cost around $177.16 for 2, 5 patch 72 hour boxes or even more if you do not have insurance coverage. Using a SingleCare Fentanyl discount card can help you to save on your prescription medication. Pay $38.37 for 2, 5 patch 72 hour boxes when you use your discount card at participating pharmacies.

How much does Fentanyl cost with insurance?

The cost of Fentanyl with your insurance plan generally depends on your coverage level and the type of health insurance policy you are enrolled in. Fentanyl may be covered only for certain health conditions and may require prior authorization. If you need help determining the cost of Fentanyl with insurance,  ask your pharmacist to run the exact prescription cost. Using a SingleCare Fentanyl savings card can also help you to save money by paying $38.37 for 2, 5 patch 72 hour boxes of Fentanyl.

Does Medicare cover Fentanyl, and how much does it cost?

Fentanyl is commonly covered by Medicare Part D and Medicare Advantage plans. However, it may be a higher-tier medication, meaning your copay will be higher. There are likely limits on how much Fentanyl you can receive within a certain period. It may also require prior authorization from your healthcare provider. SingleCare can help you to save on this medication with a Fentanyl discount card. Use your SingleCare coupon at participating local pharmacies and pay $38.37 for 2, 5 patch 72 hour boxes of Fentanyl.

How much does Fentanyl cost with Medicaid? 

Fentanyl is covered by many state Medicaid plans. However, there will likely be quantity limits, prior authorization, and suggested alternatives. Check your state Medicaid formulary to determine if Fentanyl is included.

Ways to save on Fentanyl

Fentanyl is a generic drug, so the cost is typically lower than brand-name drugs. However, because Fentanyl is dosed as a transdermal patch, out-of-pocket costs can add up. Some ways to save on your monthly cost of Fentanyl include:

  • Use a SingleCare coupon to make Fentanyl more affordable. Using a coupon will lower your cost if you pay out-of-pocket or face a high copay. However, while a coupon for a controlled substance like Fentanyl will be accepted at many locations, pharmacy policies will differ. 

  • Shop around to see the cost of Fentanyl at different pharmacies. Some may offer lower prices than competitors.

  • Look into manufacturer discounts and patient assistance programs.

  • If the cost of Fentanyl is too much, talk to your healthcare provider about alternatives.

What is the brand name of Fentanyl?

Fentanyl is a generic prescription drug. The brand-name version of this drug, Duragesic, has been discontinued.

Is there a cheaper alternative to Fentanyl? 

Other opioid pain medications are given in tablet form. These may be less expensive than Fentanyl. However, there may be reasons why a time-release patch may be a better option to treat severe or chronic pain for some people. Talk to your healthcare provider about the most effective and affordable options.

Medically reviewed by Anne JacobsonMD, MPH
Board-Certified Family Physician

Anne Jacobson, MD, MPH, is a board-certified family physician, writer, editor, teacher, and consultant. She is a graduate of University of Wisconsin School of Medicine and Public Health, and trained at West Suburban Family Medicine in Oak Park, Illinois. She later completed a fellowship in community medicine at PCC Community Wellness and a master's in Public Health at the University of Illinois-Chicago. She lives with her family near Chicago.

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Where are Fentanyl coupons from SingleCare accepted?

SingleCare is accepted at most national pharmacies and grocers, including the following:

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