Exparel Coupons & Prices

Exparel is a non-opioid prescription medication that helps to control pain after surgery which helps to improve the recovery process. This medication is not an opioid or a narcotic. It targets the specific area of your body that you had surgery, unlike opioids, which affects your entire body. There is currently no generic alternative available for this medication. The average retail price of Exparel is typically around $444.74 per 1, 20ml of 1.3% vial. Use a SingleCare Exparel discount card and pay $391.92 for this drug.

Set your location
Get alerted when the price
changes more than 10%

1 vial10ml of 1.3%Edit

Unlock members-only prices.Free signup.

You have 0.00 in available bonus savings. Bonus savings will be automatically applied to your next eligible prescription fill.

Exparel coupon at Kroger Pharmacy
$394.92
$ 391.92
$3 off with signupwith signup

Show this free card to your pharmacist.

Coupon card loading
Exparel coupon at Harris Teeter Pharmacy
$394.92
$ 391.92
$3 off with signupwith signup

Save an extra $3 on any eligible prescription! Sign up for free

Members can save even more
and it's free to join

Exparel coupon at Walmart Neighborhood Market Pharmacy
$424.13
$ 421.13
$3 off with signupwith signup
Exparel coupon at Walmart Pharmacy
$424.13
$ 421.13
$3 off with signupwith signup
Exparel coupon at Publix Pharmacy
$424.23
$ 421.23
$3 off with signupwith signup
Exparel coupon at Costco Pharmacy
$426.01
$ 423.01
$3 off with signupwith signup
$427.99
$ 424.99
$3 off with signupwith signup
$428.96
$ 425.96
$3 off with signupwith signup

About SingleCare Pricing

SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.

Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.

Prices updated: 12/20/2025

Members save the most

Save big on your prescriptions
with the free SingleCare app.
4.8 average rating
About Exparel

Exparel is a non-opioid prescription medication that helps to control pain after surgery which helps to improve the recovery process. This medication is not an opioid or a narcotic. It targets the specific area of your body that you had surgery, unlike opioids, which affects your entire body. There is currently no generic alternative available for this medication. The average retail price of Exparel is typically around $444.74 per 1, 20ml of 1.3% vial. Use a SingleCare Exparel discount card and pay $391.92 for this drug.

About Exparel

Exparel is a non-opioid prescription medication that helps to control pain after surgery which helps to improve the recovery process. This medication is not an opioid or a narcotic. It targets the specific area of your body that you had surgery, unlike opioids, which affects your entire body. There is currently no generic alternative available for this medication. The average retail price of Exparel is typically around $444.74 per 1, 20ml of 1.3% vial. Use a SingleCare Exparel discount card and pay $391.92 for this drug.

Exparel FAQs

How much does Exparel cost without insurance?

The average cost of Exparel without insurance may be around $444.74 or more. You can purchase Exparel for $391.92 per 1, 20ml of 1.3% vial when you use a SingleCare Exparel savings card. These instant savings can be redeemed at a number of popular drugstores.

How much does Exparel cost with insurance?

The cost of Exparel with your insurance plan generally depends on the level of coverage you have and the type of health insurance policy you are enrolled in. If you need help to determine the cost of Exparel with insurance, just visit your local pharmacy and ask your pharmacist to check the exact prescription cost. Using a SingleCare Exparel savings card can also help you to save money by paying $391.92 for your Exparel prescription.

Does Medicare cover Exparel and how much does it cost?

Medicare currently does not offer coverage for Exparel. You may have to end up paying the full cash price of $444.74 for this product. SingleCare's Exparel coupons can help you to reduce this cost and pay $391.92 for Exparel. Check with your local pharmacist today to find out exactly how much you can save.

Is there a generic of Exparel?

Exparel is a brand-name prescription drug manufactured by Pacira BioSciences, Inc. There is currently no generic version of this drug available.

What is Exparel?

Exparel is a non-opioid prescription medication that helps to control pain after surgery which helps to improve the recovery process. This medication is not an opioid or a narcotic. It targets the specific area of your body that you had surgery, unlike opioids, which affects your entire body. The active ingredient in Exparel is bupivacaine which is an anesthetic that works by blocking nerve impulses in the body.

Exparel is available in the form of an injectable solution. Exparel is given as an injection placed into an area under the skin near your surgical incision. You will receive this injection in a hospital or surgical setting. Your doctor will recommend an appropriate dose for you based on an assessment of your current medical condition, other drugs you are currently taking, your age, and your weight.

This medication may have a delayed effect and you may still feel numb or be unable to move the numbed area for up to five days after treatment. Before using this medication, tell your doctor if you have liver disease, heart disease, or a history of seizures. Your doctor will need to monitor you closely after your treatment is applied. Tell your doctor if you experience joint pain or stiffness.

What are the side effects of Exparel?

Along with its needed effects, Exparel may also cause unwanted side effects such as blurred vision, confusion, dizziness, faintness, irregular heartbeat, fever, or sweating. Check With your doctor or pharmacist if you experience any of these effects and they persist or worsen.

Serious allergic reactions to this medication are usually rare. However, you should seek immediate medical attention if you begin to experience symptoms of a serious allergic reaction such as itching, rash, swelling in your face or throat, severe dizziness, tightness in your chest, or trouble breathing.

Talk to your doctor or healthcare provider for professional medical advice on the risks and benefits involved with using Exparel as this is not a complete list of side effects.

Where are Exparel coupons from SingleCare accepted?

SingleCare is accepted at most national pharmacies and grocers, including the following:

Subscribe to our savings newsletter

Health education, drug info, wellness & more

By clicking 'Subscribe', I agree to SingleCare's Terms & Conditions.