Leucovorin Coupons & Prices

Leucovorin is a prescription form of folinic acid, a pre-activated and easily metabolized form of folic acid (vitamin B9). Healthcare professionals use it primarily as a "rescue" medication in people undergoing certain cancer treatments (like high-dose methotrexate) or people with severe folic acid deficiency (megaloblastic anemia). The cash price of Leucovorin averages about $36.97 per 12, 5mg tablets. Reduce your cost to $8.51 for 12, 5mg tablets by using a Leucovorin coupon from SingleCare at participating pharmacies.

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Leucovorin coupon at Kroger Pharmacy
$11.51
$ 8.51
$3 off with signupwith signup

Show this free card to your pharmacist.

This coupon is not insurance.
Leucovorin coupon at Harris Teeter Pharmacy
$11.51
$ 8.51
$3 off with signupwith signup
Leucovorin coupon at Food Lion Pharmacy
$ 14.60
Leucovorin coupon at Costco Pharmacy
$ 15.99
Leucovorin coupon at Publix Pharmacy
$28.38
$ 25.38
$3 off with signupwith signup
Leucovorin coupon at Walgreens Pharmacy
$32.07
$ 29.07
$3 off with signupwith signup
$34.99
$ 31.99
$3 off with signupwith signup

About SingleCare Pricing

SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.

Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.

Prices updated: 08/03/2026

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About Leucovorin

Leucovorin is a prescription form of folinic acid, a pre-activated and easily metabolized form of folic acid (vitamin B9). Healthcare professionals use it primarily as a "rescue" medication in people undergoing certain cancer treatments (like high-dose methotrexate) or people with severe folic acid deficiency (megaloblastic anemia). The cash price of Leucovorin averages about $36.97 per 12, 5mg tablets. Reduce your cost to $8.51 for 12, 5mg tablets by using a Leucovorin coupon from SingleCare at participating pharmacies.

Leucovorin Price History & Information

Price History for Leucovorin Calcium

12 count, Tablet, 5mg

Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.

Average 1-Month Prices for Leucovorin Calcium

12 count, Tablet, 5mg
PharmacyLeucovorin Calcium Retail PriceLeucovorin Calcium SingleCare Price
CVS Pharmacy$29.46$9.80
Walgreens$28.50$6.63
Kroger Pharmacy$20.38$10.94
Albertsons Pharmacy$39.00$23.16

These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.

About Leucovorin

Leucovorin is a prescription form of folinic acid, a pre-activated and easily metabolized form of folic acid (vitamin B9). Healthcare professionals use it primarily as a "rescue" medication in people undergoing certain cancer treatments (like high-dose methotrexate) or people with severe folic acid deficiency (megaloblastic anemia). The cash price of Leucovorin averages about $36.97 per 12, 5mg tablets. Reduce your cost to $8.51 for 12, 5mg tablets by using a Leucovorin coupon from SingleCare at participating pharmacies.

Leucovorin FAQs

Medically reviewed by Jeff FortnerPharm.D.
Licensed Pharmacist

How much is Leucovorin with SingleCare?

The generic version of Leucovorin costs $8.51 for 12, 5mg tablets with a free Leucovorin coupon from SingleCare. You could pay less depending on your Rx details. Use the dropdown menu above to update your prescription details (i.e., brand/generic, form, dosage, quantity) to get the most accurate prices of Leucovorin with SingleCare at your local pharmacies.

How much does Leucovorin cost without insurance?

Without insurance coverage, the average retail price of Leucovorin is around $36.97 for 12, 5mg tablets. SingleCare can help you save money with a Leucovorin discount coupon. Pay only $8.51 for 12, 5mg tablets for your Leucovorin prescription at participating pharmacies.

How much does Leucovorin cost with insurance?

The out-of-pocket cost of Leucovorin with insurance will vary based on the insurance plan. You may need to contact your insurance provider directly to get an accurate out-of-pocket cost for your Leucovorin prescription. You can also save on Leucovorin by using SingleCare's Leucovorin coupons. Your Leucovorin price can be discounted to $8.51 for 12, 5mg tablets with a free coupon from SingleCare.

Does Medicare cover Leucovorin?

Medicare plans offer coverage for Leucovorin. The copay cost and other out-of-pocket costs will depend on the specific Medicare plan. In some cases, SingleCare may be more affordable than your Medicare plan. To compare prices, present your SingleCare prescription drug discount card at checkout before you purchase this medication.

Does Medicaid cover Leucovorin?

Medicaid typically covers Leucovorin at a minimal cost, without restrictions, although there may be variations between states. If coverage or the out-of-pocket cost with Medicaid is a problem, consider using a SingleCare savings card instead of Medicaid. With a discount coupon from SingleCare, Leucovorin can cost as low as $8.51 for 12, 5mg tablets. 

What is the brand name for Leucovorin?

Wellcovorin was the brand-name version of Leucovorin, but its manufacturer discontinued the drug in early 2026. Today, Leucovorin is only available as a generic.

Ways to save on Leucovorin

Leucovorin is a lower-priced generic drug, but there are still a few ways to save money. 

The first step is to compare pharmacy prices for Leucovorin to find the lowest price. Search for your medication on SingleCare’s website or app and enter your zip code to find the pharmacies with the lowest Leucovorin prices near you.

Use a free Leucovorin coupon from SingleCare to lower the price of Leucovorin to $8.51 for 12, 5mg tablets. To unlock our lowest prices and earn bonus savings on other medications, sign up for SingleCare for free.

Other ways to save money on Leucovorin include applying for Medicaid or Medicare Part D Extra Help. Additionally, the prescribing healthcare provider can provide information about community services that offer Leucovorin at a discounted price, such as 340B clinics or hospitals.

Is there a cheaper alternative to Leucovorin?

There is no safe over-the-counter alternative to Leucovorin for patients undergoing chemotherapy or treating methotrexate toxicity. While standard folic acid is a highly effective, low-cost alternative for simpler conditions like nutritional folate deficiency or megaloblastic anemia, it is NOT the same thing as Leucovorin. Leucovorin (folinic acid) bypasses the enzyme dihydrofolate reductase, which is completely blocked by chemotherapy drugs like methotrexate. If a cancer patient substitutes OTC folic acid for Leucovorin, the body will not be able to process it, leading to severe, potentially fatal chemotherapy toxicity and bone marrow suppression. Never substitute OTC supplements for Leucovorin without explicit instruction from your oncologist.

How to use SingleCare for Leucovorin

You can use SingleCare coupons at most national pharmacies and grocery stores, such as Walgreens, Kroger, Walmart, CVS, Safeway, and more. Simply text, email, print, or save your free Leucovorin coupon to your mobile wallet and show your pharmacist at checkout.

Medically reviewed by Jeff FortnerPharm.D.
Licensed Pharmacist

Jeff Fortner, Pharm.D., focuses his practice and research on pharmaceutical compounding, patient-centered care in the community setting, and pharmacist-provided clinical services. He maintains a practice site at an independent community pharmacy that also specializes in non-sterile compounding and long-term care medication preparation. Dr. Fortner enjoys spending time with his wife and two young daughters, trying and sharing new craft beers, reading sci-fi/fantasy fiction, and cycling.

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Where are Leucovorin coupons from SingleCare accepted?

SingleCare is accepted at most national pharmacies and grocers, including the following:

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