Olmesartan medoxomil is a generic blood pressure drug. It belongs to a family of drugs called angiotensin receptor blockers (ARBs). It lowers blood pressure by blocking an enzyme that tightens and narrows blood vessels. Olmesartan medoxomil only comes as tablets, but a pharmacist can prepare a liquid version (oral suspension) from the tablets for easier dosing. One key warning is that olmesartan is never safe to take during pregnancy. Women should immediately inform the prescriber if they get pregnant.
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Benicar
Olmesartan medoxomil
Treats high blood pressure
Antihypertensive, angiotensin receptor blocker (ARB)
Tablet
By mouth
Olmesartan medoxomil treats high blood pressure in adults and children 6 years of age and older.
Tablet
5 mg
20 mg
40 mg
For high blood pressure:
In adults: 20–40 mg taken by mouth once daily
In children weighing 35 kilograms (77 pounds) or more: 20–40 mg taken by mouth once daily
In children weighing between 20 kilograms (44 pounds) and 35 kilograms (77 pounds) or more: 10–20 mg taken by mouth once daily
Olmesartan Medoxomil
30 tablets bottle
Olmesartan Medoxomil
20mg tablet
Olmesartan Medoxomil
40mg tablet
Olmesartan Medoxomil
5mg tablet
Take this medicine as directed. The dose may change several times at the beginning of therapy.
Do not stop taking olmesartan medoxomil until talking to the prescriber.
Take doses without regard to meals.
Swallow the tablets whole with a drink of water.
If a pharmacist prepares an oral suspension, always shake the bottle before measuring a dose. Measure doses with a calibrated oral syringe or similar measuring device provided by the pharmacist.
Store the tablets at room temperature.
Ask the prescriber what to do in case a dose is missed. Instructions may vary between healthcare providers.
Do not take extra medicine to make up for a missed dose.
This medicine is not right for everyone.
Do not use it if you are pregnant.
Do not use it if you have had an allergic reaction to olmesartan.
It is not safe to take olmesartan during pregnancy because it could harm an unborn baby. Immediately inform the doctor if you become pregnant or think you’re pregnant.
Tell the doctor if you’re breastfeeding or planning to breastfeed.
Before starting olmesartan, tell the prescriber if you have:
Kidney problems
Heart failure
Coronary artery disease
Recent strokes
Diabetes
High potassium
Olmesartan medoxomil can cause serious problems, including:
Low blood pressure
High potassium levels
Kidney problems
Elevated blood sugar
Severe allergic reactions
This medicine could lower your blood pressure too much, especially when you first use it or if you are dehydrated. Talk to the doctor if you feel dizzy or faint while taking this drug.
To avoid low blood pressure, drink plenty of fluids if you exercise, sweat more than usual, or have diarrhea or vomiting while you are using this medicine.
This medicine may cause severe chronic diarrhea with weight loss. This could occur months to years after you start taking this medicine.
Keep all appointments with healthcare providers. Regular doctor’s visits and blood tests can help prevent serious side effects.
To avoid possible drug interactions, tell the prescriber about all prescription drugs, over-the-counter medications, and supplements you take, especially:
The blood pressure drug aliskiren (contraindicated in people with diabetes)
Blood pressure drugs called ACE inhibitors
Drugs that make you pee (diuretics), particularly potassium-sparing diuretics
NSAIDs like aspirin or ibuprofen
The bipolar drug lithium
People taking the cholesterol drug colesevelam should take the day’s olmesartan dose at least four hours before or four hours after taking the colesevelam dose.
Ask your doctor before you use medicines, supplements, or salt substitutes that contain potassium.
Tell all other doctors that you’re taking olmesartan before they prescribe new medications.
Talk to a doctor if you notice any signs or symptoms of a possible serious side effect, including:
Lightheadedness, dizziness, fainting
Change in how much or how often you urinate and bloody or cloudy urine
Severe diarrhea with weight loss
Rapid weight gain, swelling in your hands, ankles, or feet
Blistering, peeling, sores, red or purple skin rash
Allergic reaction: skin rash, hives, itching, facial swelling or puffiness, mouth swelling, swelling or tingling in the throat, chest tightness, difficulty breathing,
Olmesartan medoxomil can cause serious side effects that may not have symptoms, including:
Injury or death of an unborn baby
High potassium
Headache
Dizziness
Upper respiratory tract infections
Benicar drug summary, Prescriber’s Digital Reference (PDR)
Benicar olmesartan medoxomil tablet prescribing information, DailyMed (NIH National Library of Medicine)
Olmesartan, StatPearls
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