Pifeltro is a brand-name prescription drug used in combination with other drugs to control the underlying viral infection that causes HIV/AIDS. Pifeltro is prescribed to patients who have either not been treated yet with anti-HIV drugs or who have much of the virus cleared from their body using other anti-HIV drugs. The active ingredient in Pifeltro, doravirine, prevents HIV from reproducing itself. Pifeltro costs $2,419.68, but with a SingleCare Pifeltro coupon, you will pay $1,801.42 for a Pifeltro prescription.
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SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.
Prices updated: 12/05/2025
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Pifeltro is a brand-name prescription drug used in combination with other drugs to control the underlying viral infection that causes HIV/AIDS. Pifeltro is prescribed to patients who have either not been treated yet with anti-HIV drugs or who have much of the virus cleared from their body using other anti-HIV drugs. The active ingredient in Pifeltro, doravirine, prevents HIV from reproducing itself. Pifeltro costs $2,419.68, but with a SingleCare Pifeltro coupon, you will pay $1,801.42 for a Pifeltro prescription.
Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.
| Pharmacy | Pifeltro Retail Price | Pifeltro SingleCare Price |
|---|---|---|
| CVS Pharmacy | $2168.10 | $1890.90 |
| Walgreens | $2212.20 | $1950.90 |
| Kroger Pharmacy | $2208.00 | $1804.50 |
These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.
Pifeltro is a brand-name prescription drug used in combination with other drugs to control the underlying viral infection that causes HIV/AIDS. Pifeltro is prescribed to patients who have either not been treated yet with anti-HIV drugs or who have much of the virus cleared from their body using other anti-HIV drugs. The active ingredient in Pifeltro, doravirine, prevents HIV from reproducing itself. Pifeltro costs $2,419.68, but with a SingleCare Pifeltro coupon, you will pay $1,801.42 for a Pifeltro prescription.
Uninsured customers pay an average of $2,419.68 for Pifeltro. However, the federal ADAP (AIDS Drug Assistance Program) will help uninsured HIV/AIDS patients with most or all of Pifeltro's cost, and the HarborPath ADAP Waiting List Program may help patients with Pifeltro during ADAP funding shortfalls. For uninsured patients on the ADAP waiting list who still cannot affordably fill their prescription, a SingleCare Pifeltro coupon reduces the cost to $1,801.42.
As a high-cost prescription drug, Pifeltro copay costs may vary widely depending on your insurance plan and could be very high. With SingleCare, Pifeltro costs $1,801.42, which may be lower than your copay with your insurance company. So ask your local pharmacist to compare your insurance copay to the SingleCare discount card.
Pifeltro is covered by most Medicare prescription drug plans and by Medicaid. Uninsured patients without Medicare and Medicaid can turn to ADAP for assistance. For those on the ADAP waiting list who still cannot affordably fill their prescription, a SingleCare Pifeltro coupon reduces the cost of a Pifeltro prescription $1,801.42.
Pifeltro is a brand-name drug with the active ingredient doravirine. There are no generic alternatives to Pifeltro at this time.
Pifeltro is a brand-name prescription drug used to control HIV/AIDS due to HIV-1 infection in patients who are new to HIV therapy or who have had the amount of virus in the body significantly reduced by other anti-HIV drugs. Pifeltro is always prescribed in combination with similar drugs.
The active ingredient in Pifeltro, doravirine, is an antiretroviral drug that prevents the HIV-1 virus from reproducing itself. Reducing the amount of HIV in the body helps prevent the opportunistic and life-threatening illnesses common to HIV/AIDS, such as cancer, pneumonia, and other opportunistic infections.
Pifeltro is taken as a tablet once a day with or without food. The dose will depend on what other antiretroviral drugs are also being taken, but the standard dose is 100 mg a day.
The most common side effects of Pifeltro are diarrhea, nausea, vomiting, abdominal pain, dizziness, insomnia, and fatigue. Mental and mood changes include bizarre dreams. The most serious side effect of Pifeltro is thyroid problems. Allergic reactions are rare. Get emergency medical help if you notice signs of an allergic reaction such as rash, swelling, or trouble breathing. This is not a complete list of side effects. Your physician will address your questions and concerns regarding potential side effects.
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Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
Blog articles are not medical advice. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911.
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© 2025 SingleCare Administrators. All rights reserved