What is Protopam Chloride: Uses, Warnings & Interactions

Updated May 14, 2025  •  Published Dec 30, 2020

Protopam Chloride overview

BRAND NAMES:

  • Protopam Chloride, Protopam Chloride

Generic Names:

  • Protopam Chloride

Uses:

  • Treats nerve agent poisoning.

Therapeutic Classes:

  • Nerve Gas Antidote

Forms:

  • Injectable

How it’s taken:

  • By injection

What is Protopam Chloride used for?

What form(s) does Protopam Chloride come in

  • Injectable

What are common Protopam Chloride doses?

  • Solution Reconstituted 1GM

How to take Protopam Chloride

  • Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

  • You may be taught how to give this medicine to yourself or another person. Make sure you understand all instructions before giving yourself an injection. Do not use more medicine or use it more often than your doctor tells you to.

  • Injection routeA nurse or other health provider will give you this medicine.

  • Injection routeYour doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given as a shot into one of your muscles. The injection is usually given in the thigh.

  • This medicine should be used together with atropine.

  • Injection routeA nurse or other health provider will give you this medicine.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

  • This medicine should be used together with atropine.

  • Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

  • Injection routeYour doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given as a shot into one of your muscles. The injection is usually given in the thigh.

  • You may be taught how to give this medicine to yourself or another person. Make sure you understand all instructions before giving yourself an injection. Do not use more medicine or use it more often than your doctor tells you to.

What to do if you miss a dose of Protopam Chloride

Protopam Chloride contraindications

  • This medicine is not right for everyone. You should not receive it if you had an allergic reaction to pralidoxime.

Protopam Chloride warnings

  • Blurred vision or double vision

  • Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease.

  • Dizziness, drowsiness, or muscle weakness

  • Fast heartbeat

Protopam Chloride interactions

  • Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease.

Protopam Chloride side effects

Serious Side Effects

  • Dizziness, drowsiness, or muscle weakness

  • Blurred vision or double vision

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Fast heartbeat

Less Serious Side Effects

  • Pain where the shot was given

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