Stelara is a brand-name prescription medicine indicated for the treatment of moderate to severe plaque psoriasis and psoriatic arthritis in adults and children 6 years and older. This medication may also treat moderate to severe Crohn's disease or ulcerative colitis in adults. The active ingredient in Stelara is called ustekinumab. This medication is a monoclonal antibody biologic, also classified as an interleukin-12 and -23 antagonist. The average cash price for a prescription of Stelara is around $17,022.31 for 1, 0.5ml of 45mg/0.5ml syringe. Use a Stelara coupon from SingleCare’s discount program at participating pharmacies to pay a discounted price of $3,565.83 for 1, 0.5ml of 45mg/0.5ml syringe.
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SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
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Prices updated: 12/05/2025
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Stelara is a brand-name prescription medicine indicated for the treatment of moderate to severe plaque psoriasis and psoriatic arthritis in adults and children 6 years and older. This medication may also treat moderate to severe Crohn's disease or ulcerative colitis in adults. The active ingredient in Stelara is called ustekinumab. This medication is a monoclonal antibody biologic, also classified as an interleukin-12 and -23 antagonist. The average cash price for a prescription of Stelara is around $17,022.31 for 1, 0.5ml of 45mg/0.5ml syringe. Use a Stelara coupon from SingleCare’s discount program at participating pharmacies to pay a discounted price of $3,565.83 for 1, 0.5ml of 45mg/0.5ml syringe.
Stelara is a brand-name prescription medicine indicated for the treatment of moderate to severe plaque psoriasis and psoriatic arthritis in adults and children 6 years and older. This medication may also treat moderate to severe Crohn's disease or ulcerative colitis in adults. The active ingredient in Stelara is called ustekinumab. This medication is a monoclonal antibody biologic, also classified as an interleukin-12 and -23 antagonist. The average cash price for a prescription of Stelara is around $17,022.31 for 1, 0.5ml of 45mg/0.5ml syringe. Use a Stelara coupon from SingleCare’s discount program at participating pharmacies to pay a discounted price of $3,565.83 for 1, 0.5ml of 45mg/0.5ml syringe.
Without insurance coverage, you could pay an average retail price of $17,022.31 for 1, 0.5ml of 45mg/0.5ml syringe for your Stelara prescription. Pay as low as $3,565.83 for 1, 0.5ml of 45mg/0.5ml syringe at your local participating pharmacy when you use a SingleCare Stelara coupon. Save and reduce your out-of-pocket costs at checkout at your local pharmacy with a free and easy-to-use SingleCare coupon.
The average out-of-pocket medication costs for Stelara may vary depending on your type of health plan and the level of coverage offered. Although insurance plans and costs will vary, customers can always save when they use a SingleCare discount card at participating pharmacies. Pay as low as $3,565.83 for 1, 0.5ml of 45mg/0.5ml syringe for your next Stelara prescription. Check with your insurance for the most recent information on pricing estimates. Depending on insurance, some patients may be required to purchase Stelara at a specialty pharmacy. You can also visit the Stelara website to learn about other ways you can save, such as the Stelara withME Savings Program.
In most cases, Stelara is covered by Medicare Part D or Medicare Advantage plans. The average Medicare copay price will vary based on your plan's formulary. However, many people can save more using a SingleCare savings card. Remember to ask your pharmacist at your local participating pharmacy in the United States to compare prices and maximize your savings. Visit the SingleCare website to start saving today.
Stelara is a brand-name prescription medication manufactured by Janssen Biotech Inc. Ustekinumab is the active ingredient in Stelara.
Stelara (ustekinumab) is a brand-name prescription drug approved by the U.S. Food and Drug Administration (FDA) for the treatment of plaque psoriasis, psoriatic arthritis, and moderate to severe Crohn's disease or ulcerative colitis in adults. It can also be used in children 6 and older for plaque psoriasis or psoriatic arthritis.
Stelara is classified as an immunosuppressant that blocks the naturally produced body proteins, interleukin-12 and interleukin-23, which cause inflammation.
Always read the medication guide and consult your healthcare provider for medical advice concerning the correct dosage and frequency for your medical condition. Before using Stelara, your healthcare provider will test you to ensure you have no other infections. This medication can be infused into a vein or injected under the skin. A healthcare provider will administer the first dose and may teach you how to properly inject Stelara under the skin for future doses.
Always ensure there is no discoloration, cloudiness, or particles before administering this medication. Stelara should not be injected into the same area consecutively or into the skin that is damaged, swollen, or red. Dosages are based on weight and may require adjustment by your healthcare provider if you experience a change in weight. While taking Stelara, you should not receive any live vaccines.
Some common side effects include headache, stomach problems (pain, nausea, vomiting, diarrhea), back pain, joint pain, fatigue, or infection. Injection site reactions such as bruising, swelling, itching, pain, and redness may occur.
Severe allergic reactions to Stelara are not common. However, get emergency medical help if you experience hives, trouble breathing or swallowing, or swelling of the face, lips, tongue, or throat.
Serious side effects are possible because Stelara affects your immune system. Severe infections may occur, including tuberculosis or other infections caused by viruses, bacteria, or fungi. While taking Stelara, report signs of infection to your doctor, such as fever, chills, muscle aches, cough, skin sores, fatigue, shortness of breath, weight loss, or burning when you urinate.
Individuals with a genetic condition where the body does not make any of the proteins interleukin 12 (IL-12) and interleukin 23 (IL-23) are at increased risk for certain serious infections, which can cause death. People who take Stelara may also be at higher risk for these types of infections.
Certain types of cancer, such as skin cancer, may also occur in people who take Stelara.
A rare and possibly fatal condition known as Posterior Reversible Encephalopathy Syndrome (PRES) may occur. The cause of PRES is unknown, but if it is found and treated early, most people recover. Symptoms to be aware of include seizures, headache, confusion, or changes in vision.
This is not a full list of side effects, and others may occur. Consult your doctor for additional information and questions about Stelara before you start treatment.
Stelara and Humira are both biologic medicines used to treat certain autoimmune conditions. Stelara is classified as a human interleukin-12 and -23 antagonist, while Humira is classified as a tumor necrosis factor (TNF) blocker.
Either medication can be used to treat plaque psoriasis, psoriatic arthritis, Crohn’s disease, or ulcerative colitis. Additionally, Humira has some other indications, including rheumatoid arthritis, juvenile idiopathic arthritis, ankylosing spondylitis, hidradenitis suppurativa, and uveitis.
Stelara and Humira are medications that are generally used when other treatments have not been effective. Both medications have benefits and risks to consider. Consult your healthcare provider for more information about these medications.
After receiving her doctorate from the University of Pittsburgh School of Pharmacy, Karen Berger, Pharm.D., has worked in both chain and independent community pharmacies. She currently works at an independent pharmacy in New Jersey. Dr. Berger enjoys helping patients understand medical conditions and medications—both in person as a pharmacist, and online as a medical writer and reviewer.
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Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
Blog articles are not medical advice. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911.
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© 2025 SingleCare Administrators. All rights reserved