Synerderm is a prescription moisturizing emulsion that relieves burning and itching due to eczema or allergies. Synerderm is sold as an emulsion. As a spray, it is sold under the brand name, Phlag Spray. Currently, Synerderm emulsion costs $1,523. A SingleCare Synerderm coupon reduces the price of Synerderm to $1,250.50 at participating pharmacies across the country.
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SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.
Prices updated: 12/05/2025
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Synerderm is a prescription moisturizing emulsion that relieves burning and itching due to eczema or allergies. Synerderm is sold as an emulsion. As a spray, it is sold under the brand name, Phlag Spray. Currently, Synerderm emulsion costs $1,523. A SingleCare Synerderm coupon reduces the price of Synerderm to $1,250.50 at participating pharmacies across the country.
Synerderm is a prescription moisturizing emulsion that relieves burning and itching due to eczema or allergies. Synerderm is sold as an emulsion. As a spray, it is sold under the brand name, Phlag Spray. Currently, Synerderm emulsion costs $1,523. A SingleCare Synerderm coupon reduces the price of Synerderm to $1,250.50 at participating pharmacies across the country.
The price for Synerderm emulsion averages around $1,523. With a SingleCare Synerderm discount card, a prescription for 1, 60ml of bottle of Synerderm costs $1,250.50. For all your prescription needs, a SingleCare savings card can save you as much as 80% on your purchases.
Synerderm may not be covered by health insurance plans. If it is, the copay may vary. Ask your pharmacist to compare your cost with insurance to your discounted price using a SingleCare Synerderm coupon. Synerderm's price with a SingleCare discount card may be lower than your copay. You could pay only $1,250.50 with SingleCare.
Medicare prescription drug plans do not cover prescriptions for Synerderm. For Medicare patients with a prescription for Synerderm, you’ll pay as little as $1,250.50 for 1, 60ml of bottle of Synerderm with a SingleCare Synerderm at participating pharmacies.
Synerderm is a brand-name prescription skin moisturizer emulsion with deionized water, copolymer, and palm oils. There is a wide range of over-the-counter brand-name and generic moisturizers in various formats. There is no brand-name or generic emulsion moisturizer with the same ingredients as Synerderm.
Synerderm is a brand-name prescription skin moisturizer that relieves the symptoms – itching and burning – caused by eczema (atopic dermatitis) and allergies (allergic dermatitis). Synerderm is an “emulsion,” which is not as thick as a cream and is more easily and quickly absorbed into the skin.
The active ingredients in Synerderm are deionized (demineralized) water, copolymer, and palm oils. Deionized water more quickly absorbs into the skin than normal water and doesn't cause the skin to dry out as mineralized water does. Copolymer works like a hydrogel by putting a protective barrier between the skin and the air. Palm oils are used in skin moisturizers to protect against evaporation.
Synerderm is applied to the affected area up to 5 times a day.
Synerderm is classified as a medical device rather than a drug. Some but not all common side effects of Synerderm are primarily allergic reactions to the active or inactive ingredients and include skin redness, itching, burning, or irritation.
SingleCare is accepted at most national pharmacies and grocers, including the following:
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