Tyrvaya is a prescription medication used to treat the signs and symptoms of dry eye disease. This medication is available as a nasal spray solution. Tyrvaya does not have any major safety concerns.
Tyrvaya overview
BRAND NAMES:
Tyrvaya
Generic Names:
Varenicline solution
Uses:
Treats the signs and symptoms of dry eye disease
Therapeutic Classes:
Dry eye disease agent, cholinergic agonist
Forms:
Nasal solution
How it’s taken:
Intranasal (nasal administration)
What is Tyrvaya used for?
Tyrvaya (varenicline) is a dry eye disease medication that works on specific areas of the nose to increase tear production in the eyes. Tyrvaya is used to treat the signs and symptoms of dry eye disease. This medication comes as a nasal spray solution that is used twice a day.
Expert tips for using Tyrvaya
Read through the medication guide that comes with Tyrvaya to learn the proper technique for administering the nasal spray.
For Tyrvaya administration, it’s important to resist inhaling the mist, avoid spraying into the sinuses, and ensure proper tongue placement on the roof of the mouth.
The most common side effect of Tyrvaya is sneezing, which occurs in 82% of people. Other common side effects reported in 5 to 16% of people were cough, throat irritation, and instillation-site (nose) irritation.
The dosing for Tyrvaya is 1 spray in each nostril 2 times a day about 12 hours apart.
What form(s) does Tyrvaya come in
Nasal Solution
0.03 mg/actuation (4.2 mL per bottle)
What are common Tyrvaya doses?
To treat the signs and symptoms of dry eye disease, spray Tyrvaya once in each nostril twice a day (approximately 12 hours apart).
Common Tyrvaya prescriptions
Tyrvaya
4.2ml of 0.03mg/act bottle
How to take Tyrvaya
Prime Tyrvaya before initial use by pumping seven actuations into the air away from the face. When Tyrvaya has not been used for more than five days, re-prime with one spray into the air. Do not shake.
Only use Tyrvaya in the nostril; do not spray in the eyes or mouth.
Prior to use, blow your nose if needed to clear your nostrils.
Tilt your head back slightly without lying down. Insert the applicator into the nostril, pointing the tip toward the top of the ear, leaving space between the tip of the applicator and the wall of the nose.
Place your tongue on the roof of your mouth and breathe gently while pressing the pump to release the spray.
Do not spray directly at the septum (cartilage that divides the nose into two separate chambers).
Wipe the applicator with a clean tissue after each use.
A one-month supply consists of two bottles of nasal solution. Finish the first bottle before opening the second bottle.
Store the nasal spray bottle at room temperature. Do not freeze the bottle.
This medicine should come with a medication guide. Ask your pharmacist for a copy if you do not have one.
What to do if you miss a dose of Tyrvaya
If a dose of Tyrvaya is missed, resume regular dosing at the next scheduled dose time.
Tyrvaya contraindications
Tyrvaya does not have any contraindications.
Tyrvaya warnings
It is unknown if Tyrvaya is safe to use in pregnant women. It is important to discuss pregnancy status and all medical conditions with the healthcare provider before starting this medication to determine if this is the safest dry eye disease treatment option.
It is unknown if Tyrvaya is safe to use while breastfeeding. It is important to discuss with the healthcare provider about options prior to breastfeeding while using Tyrvaya. The developmental and health benefits of breastfeeding should be considered, along with the mother’s clinical need for this medication and any potential adverse effects on the breastfed child.
The safety and efficacy of Tyrvaya in pediatric patients have not been established.
Tyrvaya interactions
Tyrvaya does not have any known drug interactions.
Tyrvaya side effects
In general, Tyrvaya is a well-tolerated medication that does not have any serious side effects.
Common side effects
Cough
Nose irritation
Sneezing
Throat irritation
Sources:
Tyrvaya Prescribing Information, DailyMed
Tyrvaya, Viatris
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