Tyrvaya Coupons & Prices

Varenicline

Tyrvaya, also known as varenicline solution, is a prescription medication for dry eye disease. It is a brand-name nasal spray not currently available in a generic form. As a highly selective cholinergic agonist, Tyrvaya works by stimulating the production of natural tears to reduce dryness and discomfort. On average, the retail price of Tyrvaya is $931.16 for 8.40, 0.03mg/act solution (quantity in ml)s. However, with a SingleCare Tyrvaya coupon, patients may be able to reduce expenses, potentially paying as low as $670.65 for 8.4, 0.03mg/act solution (quantity in ml)s at participating pharmacies.

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Tyrvaya coupon at Walgreens Pharmacy
$673.65
$ 670.65
$3 off with signupwith signup

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Tyrvaya coupon at Kroger Pharmacy
$675.31
$ 672.31
$3 off with signupwith signup

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Tyrvaya coupon at Harris Teeter Pharmacy
$675.31
$ 672.31
$3 off with signupwith signup
Tyrvaya coupon at Food Lion Pharmacy
$ 707.10
Tyrvaya coupon at CVS Pharmacy
$718.51
$ 715.51
$3 off with signupwith signup
Tyrvaya coupon at Publix Pharmacy
$723.55
$ 720.55
$3 off with signupwith signup
$725.17
$ 722.17
$3 off with signupwith signup
$725.17
$ 722.17
$3 off with signupwith signup
$728.77
$ 725.77
$3 off with signupwith signup

About SingleCare Pricing

SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.

Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.

Prices updated: 12/05/2025

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About Tyrvaya

Tyrvaya, also known as varenicline solution, is a prescription medication for dry eye disease. It is a brand-name nasal spray not currently available in a generic form. As a highly selective cholinergic agonist, Tyrvaya works by stimulating the production of natural tears to reduce dryness and discomfort. On average, the retail price of Tyrvaya is $931.16 for 8.40, 0.03mg/act solution (quantity in ml)s. However, with a SingleCare Tyrvaya coupon, patients may be able to reduce expenses, potentially paying as low as $670.65 for 8.4, 0.03mg/act solution (quantity in ml)s at participating pharmacies.

Tyrvaya Price History & Information

Price History for Tyrvaya

8.4 count, solution (quantity in ml), 0.03mg/act

Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.

Average 1-Month Prices for Tyrvaya

8.4 count, solution (quantity in ml), 0.03mg/act
PharmacyTyrvaya Retail PriceTyrvaya SingleCare Price
CVS Pharmacy$810.01$720.97
Walmart$822.44$725.17
Walgreens$822.02$726.26
Kroger Pharmacy$822.53$675.28

These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.

About Tyrvaya

Tyrvaya, also known as varenicline solution, is a prescription medication for dry eye disease. It is a brand-name nasal spray not currently available in a generic form. As a highly selective cholinergic agonist, Tyrvaya works by stimulating the production of natural tears to reduce dryness and discomfort. On average, the retail price of Tyrvaya is $931.16 for 8.40, 0.03mg/act solution (quantity in ml)s. However, with a SingleCare Tyrvaya coupon, patients may be able to reduce expenses, potentially paying as low as $670.65 for 8.4, 0.03mg/act solution (quantity in ml)s at participating pharmacies.

Tyrvaya FAQs

Medically reviewed by Gerardo SisonPharm.D.
Licensed Pharmacist

How much does Tyrvaya cost without insurance?

Without insurance coverage, Tyrvaya can cost an average retail price of $931.16 for 8.40, 0.03mg/act solution (quantity in ml)s. Costs for cash-paying patients and those without health insurance may vary, however, depending on pharmacy location and other factors. With SingleCare's discount program, the price could be lowered to $670.65 for 8.4, 0.03mg/act solution (quantity in ml)s. Compare cash prices with discounts on the SingleCare website for maximum savings. 

How much does Tyrvaya cost with insurance?

Tyrvaya may be covered by some health insurance plans. However, the cost with insurance depends on the specific plan and its formulary. While many commercial insurance plans may cover a portion of the cost, patients may be responsible for out-of-pocket costs, such as copays and coinsurance amounts. Consult your insurance provider or pharmacist to determine the exact cost of your monthly prescription. In some cases, the savings from SingleCare might even surpass what your insurance company offers.

Does Medicare cover Tyrvaya and how much does it cost?

Medicare plans may help cover the cost of Tyrvaya. However, medicare coverage will vary based on the plan and the prescription details. Those without Medicare can still benefit from SingleCare's discounts, often finding lower prices with SingleCare than with Medicare itself. Always compare the costs of your medicines to potentially get a discounted price, which could be as low as $670.65 for 8.4, 0.03mg/act solution (quantity in ml)s.

Is there a generic of Tyrvaya?

Currently, Tyrvaya is a brand-name drug with no generic equivalent available. It is currently manufactured by Oyster Point Pharma. The patent for Tyrvaya is expected to expire in 2035, when a generic version may be released. 

What is Tyrvaya?

Tyrvaya is a prescription nasal spray designed to treat symptoms of dry eye disease. It may be prescribed when other treatments have not provided sufficient relief. Tyrvaya works by activating certain receptors in the nervous system, which in turn stimulates natural tear production. As a result, Tyrvaya may help relieve the discomfort associated with dry eye disease, making it a potential option for many patients.

What doses of Tyrvaya are available?

Tyrvaya comes as a nasal spray that delivers 0.03 mg of varenicline with each spray. The typical dosage is one spray in each nostril twice daily, with each dose separated by around 12 hours. The nasal spray should be primed with seven actuations before the first use and reprimed with one actuation if the nasal spray isn’t used for more than five days. Always use Tyrvaya under the guidance and expertise of a licensed healthcare provider. 

What are the side effects of Tyrvaya?

Common side effects of Tyrvaya include:

  • Mild irritation or discomfort in the nose

  • Sneezing

  • Cough

More serious adverse effects are possible, such as severe nasal irritation or allergic reactions. Consult your doctor or healthcare provider for additional information and professional medical advice regarding potential side effects of Tyrvaya. 

Does Tyrvaya work better than Restasis?

Both Tyrvaya and Restasis are effective medicines for treating dry eye disease. However, they work in different ways. Tyrvaya is a nasal spray that contains a cholinergic agonist called varenicline, while Restasis is a prescription eye drop that contains an immunosuppressant called cyclosporine. According to some clinical trials, Tyrvaya nasal spray may be more effective than Restasis eye drops in improving tear production for people with dry eye disease. 

Does Tyrvaya work for dry eyes?

Yes, Tyrvaya is specifically designed to treat dry eye disease. It works by stimulating the body's natural tear production, which may help relieve the symptoms of dry eyes. Consult a healthcare provider for any questions or concerns about the use of Tyrvaya. This medication may only be prescribed after an appropriate diagnosis.

Medically reviewed by Gerardo SisonPharm.D.
Licensed Pharmacist

Gerardo Sison, Pharm.D., graduated from the University of Florida. He has worked in both community and hospital settings, providing drug information and medication therapy management services. As a medical writer, he hopes to educate and empower patients to better manage their health and navigate their treatment plans.

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Where are Tyrvaya coupons from SingleCare accepted?

SingleCare is accepted at most national pharmacies and grocers, including the following:

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