Vasculera is an FDA-approved prescription medical food used to support the management of hemorrhoids and venous problems, such as chronic venous insufficiency, a condition that can be characterized by varicose veins, spider veins, venous ulcers, leg swelling, or blood clotting in the veins. The active ingredients in Vasculera are purified diosmin glycoside (MPFF) and alka-4 complex. The generic name of Vasculera is diosmiplex. Vasculera's cash price can be around $5,558.98 for 1, 30 tablets bottle, but with a SingleCare Vasculera coupon, the price is only $4,914.82. SingleCare Vasculera coupons are welcomed at participating pharmacies.
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SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
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Prices updated: 12/19/2025
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Vasculera is an FDA-approved prescription medical food used to support the management of hemorrhoids and venous problems, such as chronic venous insufficiency, a condition that can be characterized by varicose veins, spider veins, venous ulcers, leg swelling, or blood clotting in the veins. The active ingredients in Vasculera are purified diosmin glycoside (MPFF) and alka-4 complex. The generic name of Vasculera is diosmiplex. Vasculera's cash price can be around $5,558.98 for 1, 30 tablets bottle, but with a SingleCare Vasculera coupon, the price is only $4,914.82. SingleCare Vasculera coupons are welcomed at participating pharmacies.
Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.
These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.
Vasculera is an FDA-approved prescription medical food used to support the management of hemorrhoids and venous problems, such as chronic venous insufficiency, a condition that can be characterized by varicose veins, spider veins, venous ulcers, leg swelling, or blood clotting in the veins. The active ingredients in Vasculera are purified diosmin glycoside (MPFF) and alka-4 complex. The generic name of Vasculera is diosmiplex. Vasculera's cash price can be around $5,558.98 for 1, 30 tablets bottle, but with a SingleCare Vasculera coupon, the price is only $4,914.82. SingleCare Vasculera coupons are welcomed at participating pharmacies.
You will pay an average retail price $5,558.98 for 1, 30 tablets bottle of Vasculera without insurance. With a SingleCare Vasculera prescription discount card, you could pay our lowest price of $4,914.82.
Vasculera copay costs may vary depending on your insurance plan. Some insurance plans may not cover Vasculera. If your insurance plan covers Vasculera, you should ask your pharmacist to compare your SingleCare price with your insurance copay. With SingleCare, Vasculera costs as little as $4,914.82 for 1, 30 tablets bottle, which may be lower than your copay.
Vasculera is usually not covered by Medicare prescription drug plans. For patients with Medicare, consider bringing a SingleCare Vasculera coupon to your pharmacist. With a SingleCare prescription savings card, you pay our Vasculera discount price of $4,914.82 for 1, 30 tablets bottle.
Vasculera is a brand-name prescription medical food product that contains diosmin and alkaline granules. The generic name of Vasculera is diosmiplex. Generic versions of Vasculera are not available at this time.
Vasculera is a prescription medical food product used to support the management of hemorrhoids and chronic venous insufficiency. Chronic venous insufficiency (CVI) is a condition that develops when the walls or valves in the veins lose the ability to push blood back to the heart. Blood pools in the veins, causing swelling and blood clots. Chronic venous insufficiency may progress into chronic venous disease (CVD) which can lead to varicose veins, spider veins, venous ulcers, swelling in the legs, and blood clotting in the veins.
Vasculera contains purified diosmin glycoside, a flavonoid found in the peels of citrus fruits. It also contains alkaline granules in the form of alka-4 complex. Diosmin is classified as a phlebotonic, which is a small class of drugs that increases the muscle tone in veins. The diosmin in Vasculera is combined with alka-4 complex to create diosmiplex.
Chronic venous insufficiency and the resulting high blood pressure in the veins often causes blood acidosis – higher than normal acid in the blood. The alkali granules in Vasculera are intended to increase the pH of the blood to normal levels.
Vasculera is taken as a tablet once per day or as directed by a physician.
The most common side effects of Vasculera may include an upset stomach, headache, leg cramps, swelling in the limbs, and a mild rash. Allergic reactions are possible with Vasculera. Seek medical attention if you experience hives, trouble breathing, or swelling of the face, mouth, or tongue.
This is not a complete list of side effects. Consult a healthcare provider for other possible side effects, drug interactions, warnings, and precautions associated with Vasculera.
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