Zioptan Coupons & Prices

Tafluprost (Pf)

Zioptan is a Prostaglandins - Ophthalmic class medication produced by Thea Pharma. It is an eye drop used to treat high pressure in the eye due to open-angle glaucoma or ocular hypertension. The average retail price of Zioptan is $288.58 per 3, 10 solution boxes, but you can pay just $55.53 for 6, 5 solution boxes of Zioptan with a SingleCare prescription drug discount card. Zioptan is a brand-name drug.

Set your location
Get alerted when the price
changes more than 10%

1 box5 solutionEdit

Unlock members-only prices.Free signup.

You have 0.00 in available bonus savings. Bonus savings will be automatically applied to your next eligible prescription fill.

Zioptan coupon at CVS Pharmacy
$58.53
$ 55.53
$3 off with signupwith signup

Show this free card to your pharmacist.

Coupon card loading
Zioptan coupon at Walgreens Pharmacy
$117.07
$ 114.07
$3 off with signupwith signup

Save an extra $3 on any eligible prescription! Sign up for free

Members can save even more
and it's free to join

Zioptan coupon at Publix Pharmacy
$141.32
$ 138.32
$3 off with signupwith signup
Zioptan coupon at Walmart Neighborhood Market Pharmacy
$165.23
$ 162.23
$3 off with signupwith signup
Zioptan coupon at Walmart Pharmacy
$165.23
$ 162.23
$3 off with signupwith signup
Zioptan coupon at Food Lion Pharmacy
$ 162.80
$198.01
$ 195.01
$3 off with signupwith signup
$198.01
$ 195.01
$3 off with signupwith signup
$ 217.05

About SingleCare Pricing

SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.

Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.

Prices updated: 12/05/2025

Members save the most

Save big on your prescriptions
with the free SingleCare app.
4.8 average rating
About Zioptan

Zioptan is a Prostaglandins - Ophthalmic class medication produced by Thea Pharma. It is an eye drop used to treat high pressure in the eye due to open-angle glaucoma or ocular hypertension. The average retail price of Zioptan is $288.58 per 3, 10 solution boxes, but you can pay just $55.53 for 6, 5 solution boxes of Zioptan with a SingleCare prescription drug discount card. Zioptan is a brand-name drug.

Zioptan Price History & Information

Price History for Zioptan (Brand) & Tafluprost (Pf) (Generic)

6 count, plas cont, 5 solution

Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.

Average 1-Month Prices for Zioptan (Brand) & Tafluprost (Pf) (Generic)

6 count, plas cont, 5 solution
PharmacyZioptan Retail PriceTafluprost (Pf) Retail PriceTafluprost (Pf) SingleCare Price
CVS Pharmacy$317.10$233.10$72.30
Walmart-$262.20$135.15
Walgreens$320.10$153.87$94.10
Kroger Pharmacy$318.90$263.70$197.22
Albertsons Pharmacy$326.10$228.45$150.15

These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.

About Zioptan

Zioptan is a Prostaglandins - Ophthalmic class medication produced by Thea Pharma. It is an eye drop used to treat high pressure in the eye due to open-angle glaucoma or ocular hypertension. The average retail price of Zioptan is $288.58 per 3, 10 solution boxes, but you can pay just $55.53 for 6, 5 solution boxes of Zioptan with a SingleCare prescription drug discount card. Zioptan is a brand-name drug.

Zioptan FAQs

Medically reviewed by Karen BergerPharm.D.
Licensed Pharmacist

How much does Zioptan cost without insurance?

The standard out-of-pocket cost of Zioptan without health insurance is $288.58 per 3, 10 solution boxes, though you can save using a SingleCare Zioptan coupon to pay only $55.53 for 6, 5 solution boxes of Zioptan. If you don’t have access to an insurance plan, you can still use SingleCare for free Zioptan savings.

How much does Zioptan cost with insurance?

Each insurance formulary is different and may or may not cover Zioptan. The cost of Zioptan with insurance coverage varies depending on your plan - check with your insurance provider for specific drug coverage and copay details. Insurance plans may be more likely to cover the generic formulation of Zioptan.

If your insurance does not cover Zioptan, you can use SingleCare to get discounts on Zioptan at your participating pharmacy. You can also use SingleCare coupons if you have Medicare or Medicaid. If Medicare or Medicaid don’t cover your Zioptan prescription, you can use SingleCare instead. Go to the SingleCare website or app to compare the lowest price of Zioptan with SingleCare versus your copay with insurance or Medicare.

Does Medicare cover Zioptan, and how much does it cost?

Zioptan costs with Medicare will vary by plan, prescription, and coverage stage. Refer to your plan’s drug formulary to determine whether your Medicare Part D or Medicare Advantage plan covers Zioptan and how much the copay or coinsurance is. Choose generic for additional cost savings. 

If Zioptan is not covered by Medicare or if you have not met your plan’s deductible, you may have to pay the full price of $288.58 for 3, 10 solution boxes. Using a SingleCare coupon for Zioptan could save you more money than Medicare. Our lowest price for Zioptan is currently $55.53 for 6, 5 solution boxes.

Is there a generic of Zioptan?

Zioptan is a brand name drug made by Thea Pharma. The generic version of Zioptan is Tafluprost and is much cheaper than the price of Zioptan, which is $288.58 per 3, 10 solution boxes, but uses the same active ingredient as Zioptan. Use a SingleCare prescription drug discount card to pay $55.53 for 6, 5 solution boxes.

What is Zioptan? 

Zioptan is an eye drop used to decrease intraocular pressure (fluid pressure in the eye) in people with open-angle glaucoma or ocular hypertension. It is classified as a prostaglandin analog and works by increasing the flow of natural eye fluids from the eye(s), which lowers the pressure in the eye(s). 

The usual dose of Zioptan is one drop in the affected eye or eyes once daily in the evening. Do not use this medicine more than instructed because doing so could interfere with how the medication works. 

Wash your hands before using these eye drops. After instilling your eye drops as directed, wait at least 5 minutes before using any other eye drops. 

Each single-use bottle of Zioptan is for one use only (in one or both eyes). After using, throw the bottle away after one use, even if some medicine remains in the bottle. 

Store unopened cartons or foil pouches in the refrigerator. Do not freeze Zioptan. After opening the foil pouch, store it at room temperature, away from direct light, heat, and moisture. Once you open the pouch, use the medication within 28 days.

If you miss a dose of Zioptan, use it as soon as you remember. If it is almost time for the next dose, skip the missed dose. Do not use extra eye drops to make up for a missed dose. 

What are the side effects of Zioptan?

Common side effects of Zioptan are local to the eye, such as redness, stinging, itching, dryness, pain, and irritation. There may be eyelash growth or darkening of the eyelashes, color changes of the iris, and darkening of the eyelids and skin around the eyes. The change in color of the eyes, eyelids, and lashes may be gradual but may be permanent, even after the treatment ends—and may occur only in the eye being treated. 

Tell your healthcare provider right away if you have an eye infection, injury, vision changes, or if you need to have any type of surgery. Notify your healthcare provider if you have eye pain, redness, itchy or watery eyes, or sensitivity to light. 

This is not a full list of side effects, and others may occur. Side effects can be serious, including macular edema (swelling of the retina), uveitis (inflammation inside the eye), iritis (swelling/inflammation of the iris), and cataracts (clouding of the lens of the eye). Before using  Zioptan, talk to your healthcare provider about potential side effects. 

Are there any known drug interactions with Zioptan? 

When taking Zioptan, you should not use any other eye drops in the prostaglandin analog class, such as Xalatan (latanoprost), Travatan Z (travoprost), or Lumigan (bimatoprost). Using two drugs from the same class will not help your condition and can cause intraocular pressure to increase. 

Are there any known contraindications with Zioptan? 

Zioptan is not appropriate for everyone. Before using Zioptan, tell your healthcare provider about your medical history and any medical conditions. People allergic to tafluprost or similar drugs should not take Zioptan. Also, Zioptan should be used with caution in certain individuals, such as people at risk for macular edema, people with no lens in the eye, and people with active eye inflammation. 

Which is better, latanoprost or Zioptan? 

Because both drugs are in the same drug class, they work the same way and have similar side effects. Talk to your healthcare provider for professional medical advice and more information about both drugs.

Medically reviewed by Karen BergerPharm.D.
Licensed Pharmacist

After receiving her doctorate from the University of Pittsburgh School of Pharmacy, Karen Berger, Pharm.D., has worked in both chain and independent community pharmacies. She currently works at an independent pharmacy in New Jersey. Dr. Berger enjoys helping patients understand medical conditions and medications—both in person as a pharmacist, and online as a medical writer and reviewer.

... 

Where are Zioptan coupons from SingleCare accepted?

SingleCare is accepted at most national pharmacies and grocers, including the following:

Subscribe to our savings newsletter

Health education, drug info, wellness & more

By clicking 'Subscribe', I agree to SingleCare's Terms & Conditions.