Xtampza ER is a prescription medication used to treat severe chronic pain that requires around-the-clock treatment with an opioid. It is a brand-name pain medication that carries a risk of opioid addiction, overdose, and even death. No generic equivalent of Xtampza ER is currently available in the United States. The average retail price of Xtampza ER is $509.67 for 60, 9mg capsules er 12 hour abuse-deterrent of Xtampza ER. You may be able to save on this cash price with an Xtampza ER coupon from SingleCare and pay $383.78 for 60, 9mg capsules er 12 hour abuse-deterrent at participating pharmacies.
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SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
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Prices updated: 12/05/2025
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Xtampza ER is a prescription medication used to treat severe chronic pain that requires around-the-clock treatment with an opioid. It is a brand-name pain medication that carries a risk of opioid addiction, overdose, and even death. No generic equivalent of Xtampza ER is currently available in the United States. The average retail price of Xtampza ER is $509.67 for 60, 9mg capsules er 12 hour abuse-deterrent of Xtampza ER. You may be able to save on this cash price with an Xtampza ER coupon from SingleCare and pay $383.78 for 60, 9mg capsules er 12 hour abuse-deterrent at participating pharmacies.
Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.
| Pharmacy | Xtampza Er Retail Price | Xtampza Er SingleCare Price |
|---|---|---|
| CVS Pharmacy | $472.20 | $429.60 |
| Walmart | $477.00 | $477.00 |
| Walgreens | $483.60 | $427.80 |
| Kroger Pharmacy | $477.00 | $424.20 |
These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.
Xtampza ER is a prescription medication used to treat severe chronic pain that requires around-the-clock treatment with an opioid. It is a brand-name pain medication that carries a risk of opioid addiction, overdose, and even death. No generic equivalent of Xtampza ER is currently available in the United States. The average retail price of Xtampza ER is $509.67 for 60, 9mg capsules er 12 hour abuse-deterrent of Xtampza ER. You may be able to save on this cash price with an Xtampza ER coupon from SingleCare and pay $383.78 for 60, 9mg capsules er 12 hour abuse-deterrent at participating pharmacies.
Without insurance, the average cost of Xtampza ER is $509.67 for 60, 9mg capsules er 12 hour abuse-deterrent at your local pharmacy. Prescription prices vary depending on various factors, including pharmacy location and the prescribed dose. To save money on your out-of-pocket costs for Xtampza ER, you could use a SingleCare prescription discount card on your refill. SingleCare may help reduce the price to as low as $383.78 for 60, 9mg capsules er 12 hour abuse-deterrent.
The cost of Xtampza ER with insurance tends to vary by insurance plan, coverage, and the amount prescribed. Generally, insurance will cover some portion of the prescription medication, but you may be responsible for copays or coinsurance. Consult your insurance provider or pharmacist for accurate pricing estimates and insurance coverage details for Xtampza ER. In some cases, the SingleCare discount card may offer better savings than your insurance.
Some Medicare plans may cover Xtampza ER, but you can refer to your plan’s drug formulary for the most recent information. Although Medicare may cover part of the cost, you could still save more by using a SingleCare coupon. The SingleCare prescription savings card could reduce your cost to as low as $383.78 for 60, 9mg capsules er 12 hour abuse-deterrent.
Xtampza ER is a brand-name prescription drug. There are currently no generic versions of Xtampza ER available.
Xtampza ER is a strong prescription pain medicine used to treat chronic, severe pain that requires a long-term opioid for relief. It is an extended-release medication, meaning it provides pain relief over a prolonged period. Xtampza ER works by binding to opioid receptors in the central nervous system, disrupting pain signals.
You should only use Xtampza ER as prescribed by your healthcare provider. The dosage of Xtampza ER will vary depending on the severity of the pain and the individual’s overall condition. Get medical advice from your doctor before discontinuing Xtampza ER.
To ensure that the benefits of opioid analgesics outweigh the risks, the FDA requires a Risk Evaluation and Mitigation Strategy (REMS) for such products. Under the requirements of the REMS, drug companies with approved opioid analgesic products must make REMS-compliant education programs available to healthcare providers and prescribers of these drugs.
Common side effects of Xtampza ER may include:
Drowsiness
Fatigue
Nausea
Constipation
Vomiting
Headache
Dizziness
Upset stomach
Serious side effects can also occur, such as:
Misuse, addiction, and overdose
Respiratory depression
Neonatal opioid withdrawal syndrome
Concomitant use of opioids with benzodiazepines or other central nervous system (CNS) depressants, including alcohol, may lead to severe drowsiness, trouble breathing, coma, and even death. Tell your healthcare provider about any medical conditions you have or medications you take.
Keep Xtampza ER out of the reach of children. Accidental ingestion of even one dose of this medication, especially by children, can result in an overdose of oxycodone and fatal respiratory depression.
This is not a complete list of the possible side effects of Xtampza ER, and others can occur. Consult a healthcare provider for additional information on potential side effects and other precautions before taking Xtampza ER. You may also report any unlisted side effects to the FDA.
What medication is similar to Xtampza ER?
Xtampza ER is a brand-name medication containing oxycodone in an extended-release form. OxyContin is a similar medication prescribed for chronic pain that contains an extended-release form of oxycodone. Consult a healthcare provider for the most appropriate alternative, as not all versions of oxycodone are equivalent. For example, Xtampza 36 mg is equivalent to 40 mg of oxycodone HCl, while Xtampza 27 mg is equivalent to 30 mg of oxycodone HCl.
Gerardo Sison, Pharm.D., graduated from the University of Florida. He has worked in both community and hospital settings, providing drug information and medication therapy management services. As a medical writer, he hopes to educate and empower patients to better manage their health and navigate their treatment plans.
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Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
Blog articles are not medical advice. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911.
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© 2025 SingleCare Administrators. All rights reserved