Zanaflex Coupons & Prices

Tizanidine Hcl

Zanaflex (tizanidine) is an FDA-approved short-acting muscle relaxant prescribed to patients who suffer from muscle spasms or muscle rigidity due to multiple sclerosis, spinal cord injury, or other conditions. Zanaflex works by blocking nerve impulses to the muscles that cause involuntary muscle contractions. Continue reading the FAQs section for more information about Zanaflex, how it works, how much it costs, and how you can save money on your Zanaflex prescription. Zanaflex cost is normally $4,283.31 for 60, 8mg capsules of Zanaflex at full retail price. A SingleCare Zanaflex coupon reduces the price to $4.46 for 30, 4mg tablets of generic Zanaflex at participating pharmacies.

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Zanaflex coupon at Kroger Pharmacy
$7.46
$ 4.46
$3 off with signupwith signup

Show this free card to your pharmacist.

This coupon is not insurance.
Zanaflex coupon at Harris Teeter Pharmacy
$7.46
$ 4.46
$3 off with signupwith signup
Zanaflex coupon at Walmart Neighborhood Market Pharmacy
$ 9.00
Zanaflex coupon at Walmart Pharmacy
$ 9.00
Zanaflex coupon at Food Lion Pharmacy
$ 10.02
Zanaflex coupon at Walgreens Pharmacy
$14.73
$ 11.73
$3 off with signupwith signup
$ 13.99
$19.33
$ 16.33
$3 off with signupwith signup
$24.93
$ 21.93
$3 off with signupwith signup

About SingleCare Pricing

SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.

Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.

Prices updated: 03/20/2026

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4.8 average rating
About Zanaflex

Zanaflex (tizanidine) is an FDA-approved short-acting muscle relaxant prescribed to patients who suffer from muscle spasms or muscle rigidity due to multiple sclerosis, spinal cord injury, or other conditions. Zanaflex works by blocking nerve impulses to the muscles that cause involuntary muscle contractions. Continue reading the FAQs section for more information about Zanaflex, how it works, how much it costs, and how you can save money on your Zanaflex prescription. Zanaflex cost is normally $4,283.31 for 60, 8mg capsules of Zanaflex at full retail price. A SingleCare Zanaflex coupon reduces the price to $4.46 for 30, 4mg tablets of generic Zanaflex at participating pharmacies.

About Zanaflex

Zanaflex (tizanidine) is an FDA-approved short-acting muscle relaxant prescribed to patients who suffer from muscle spasms or muscle rigidity due to multiple sclerosis, spinal cord injury, or other conditions. Zanaflex works by blocking nerve impulses to the muscles that cause involuntary muscle contractions. Continue reading the FAQs section for more information about Zanaflex, how it works, how much it costs, and how you can save money on your Zanaflex prescription. Zanaflex cost is normally $4,283.31 for 60, 8mg capsules of Zanaflex at full retail price. A SingleCare Zanaflex coupon reduces the price to $4.46 for 30, 4mg tablets of generic Zanaflex at participating pharmacies.

Zanaflex FAQs

Medically reviewed by Gerardo SisonPharm.D.
Licensed Pharmacist

How much does Zanaflex cost without insurance?

At most pharmacies, the cash price of Zanaflex will be $4,283.31 for 60, 8mg capsules of Zanaflex for uninsured patients. That same prescription, however, may only cost $4.46 for 30, 4mg tablets of generic Zanaflex using a SingleCare prescription savings card. SingleCare is accepted at major pharmacies throughout the country, such as CVS, Target, Longs Drugs, Walmart, Walgreens, Duane Reade, and others.

How much does Zanaflex cost with insurance?

The cost of Zanaflex will differ greatly depending on your insurance plan. With SingleCare, Zanaflex costs only $4.46 for 30, 4mg tablets of generic Zanaflex. You should consider asking your pharmacist to compare your Zanaflex insurance copay to your SingleCare Zanaflex discount card. Your SingleCare price may be lower than your insurance copay.

Does Medicare cover Zanaflex and how much does it cost?

Some Medicare insurance plans may cover the cost of Zanaflex in either tablet or capsule form. However, the generic version of Zanaflex, tizanidine, is often preferred by Medicare Part D and Medicare Advantage plans. For Medicare patients who are underinsured, a SingleCare Zanaflex discount card could lower the price of Zanaflex to $4.46.

Is there a generic of Zanaflex?

Zanaflex is a prescription brand-name drug taken in tablet or capsule form. A generic version of Zanaflex is available in both tablet and capsule form. Generic manufacturers include Zydus Pharmaceuticals, Apotex, Novast Laboratories, and many others. 

The tablet and capsule formulations of Zanaflex are not interchangeable. Zanaflex tablets cannot be substituted for Zanaflex capsules and vice versa.

What is Zanaflex?

Zanaflex (tizanidine) is a short-acting muscle relaxant that relieves spasticity (involuntary contractions, spasms, or tensing of muscles). It is prescribed to treat patients with multiple sclerosis, spinal cord injury, cerebral palsy, stroke, or traumatic brain injury who regularly experience muscle spasms or rigidity.

Spasticity occurs when nerves in the spinal cord become “disconnected” from the control centers in the brain. Zanaflex works by blocking nerve impulses to the muscles to reduce involuntary muscle contractions.

Zanaflex is available in both a tablet and capsule form. The capsule form has been shown to work more quickly than the tablet, so a Zanaflex or generic tizanidine tablet cannot be substituted for a Zanaflex capsule. This medication should only be used under the guidance of a healthcare provider. 

Zanaflex is sometimes prescribed off-label to treat symptoms of fibromyalgia.

What are the side effects of Zanaflex?

Common side effects of Zanaflex include, but are not limited to, drowsiness, dizziness, dry mouth, weakness, constipation, and nervousness. Other possible side effects include urinary tract infection, abnormal liver function tests, speech problems, sore throat, and runny nose.

Serious side effects of Zanaflex may include low blood pressure (hypotension), liver injury, hallucinations, and kidney problems. Consult a healthcare provider if you experience any side effects while using Zanaflex. 

Allergic reactions are rare but may present as certain signs and symptoms, such as trouble breathing, hives, and swelling of the face or throat. 

This is not a complete list of side effects. Consult your doctor or healthcare professional for additional information and medical advice regarding other possible side effects or drug interactions.

Medically reviewed by Gerardo SisonPharm.D.
Licensed Pharmacist

Gerardo Sison, Pharm.D., graduated from the University of Florida. He has worked in both community and hospital settings, providing drug information and medication therapy management services. As a medical writer, he hopes to educate and empower patients to better manage their health and navigate their treatment plans.

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Where are Zanaflex coupons from SingleCare accepted?

SingleCare is accepted at most national pharmacies and grocers, including the following:

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