Zanaflex (tizanidine) is an FDA-approved short-acting muscle relaxant prescribed to patients who suffer from muscle spasms or muscle rigidity due to multiple sclerosis, spinal cord injury, or other conditions. Zanaflex works by blocking nerve impulses to the muscles that cause involuntary muscle contractions. Continue reading the FAQs section for more information about Zanaflex, how it works, how much it costs, and how you can save money on your Zanaflex prescription. Zanaflex cost is normally $131.20 for 30, 4mg tablets of Zanaflex at full retail price. A SingleCare Zanaflex coupon reduces the price to $4.46 for 30, 4mg tablets of generic Zanaflex at participating pharmacies.
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SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
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Prices updated: 12/20/2025
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Zanaflex (tizanidine) is an FDA-approved short-acting muscle relaxant prescribed to patients who suffer from muscle spasms or muscle rigidity due to multiple sclerosis, spinal cord injury, or other conditions. Zanaflex works by blocking nerve impulses to the muscles that cause involuntary muscle contractions. Continue reading the FAQs section for more information about Zanaflex, how it works, how much it costs, and how you can save money on your Zanaflex prescription. Zanaflex cost is normally $131.20 for 30, 4mg tablets of Zanaflex at full retail price. A SingleCare Zanaflex coupon reduces the price to $4.46 for 30, 4mg tablets of generic Zanaflex at participating pharmacies.
Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.
| Pharmacy | Zanaflex Retail Price | Tizanidine Hcl Retail Price | Tizanidine Hcl SingleCare Price |
|---|---|---|---|
| CVS Pharmacy | - | $37.50 | $36.15 |
| Walmart | $99.30 | $8.55 | $8.55 |
| Walgreens | - | $19.50 | $16.87 |
| Kroger Pharmacy | - | $34.30 | $5.74 |
| Albertsons Pharmacy | - | $39.44 | $6.95 |
These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.
Zanaflex (tizanidine) is an FDA-approved short-acting muscle relaxant prescribed to patients who suffer from muscle spasms or muscle rigidity due to multiple sclerosis, spinal cord injury, or other conditions. Zanaflex works by blocking nerve impulses to the muscles that cause involuntary muscle contractions. Continue reading the FAQs section for more information about Zanaflex, how it works, how much it costs, and how you can save money on your Zanaflex prescription. Zanaflex cost is normally $131.20 for 30, 4mg tablets of Zanaflex at full retail price. A SingleCare Zanaflex coupon reduces the price to $4.46 for 30, 4mg tablets of generic Zanaflex at participating pharmacies.
At most pharmacies, the cash price of Zanaflex will be $131.20 for 30, 4mg tablets of Zanaflex for uninsured patients. That same prescription, however, may only cost $4.46 for 30, 4mg tablets of generic Zanaflex using a SingleCare prescription savings card. SingleCare is accepted at major pharmacies throughout the country, such as CVS, Target, Longs Drugs, Walmart, Walgreens, Duane Reade, and others.
The cost of Zanaflex will differ greatly depending on your insurance plan. With SingleCare, Zanaflex costs only $4.46 for 30, 4mg tablets of generic Zanaflex. You should consider asking your pharmacist to compare your Zanaflex insurance copay to your SingleCare Zanaflex discount card. Your SingleCare price may be lower than your insurance copay.
Some Medicare insurance plans may cover the cost of Zanaflex in either tablet or capsule form. However, the generic version of Zanaflex, tizanidine, is often preferred by Medicare Part D and Medicare Advantage plans. For Medicare patients who are underinsured, a SingleCare Zanaflex discount card could lower the price of Zanaflex to $4.46.
Zanaflex is a prescription brand-name drug taken in tablet or capsule form. A generic version of Zanaflex is available in both tablet and capsule form. Generic manufacturers include Zydus Pharmaceuticals, Apotex, Novast Laboratories, and many others.
The tablet and capsule formulations of Zanaflex are not interchangeable. Zanaflex tablets cannot be substituted for Zanaflex capsules and vice versa.
Zanaflex (tizanidine) is a short-acting muscle relaxant that relieves spasticity (involuntary contractions, spasms, or tensing of muscles). It is prescribed to treat patients with multiple sclerosis, spinal cord injury, cerebral palsy, stroke, or traumatic brain injury who regularly experience muscle spasms or rigidity.
Spasticity occurs when nerves in the spinal cord become “disconnected” from the control centers in the brain. Zanaflex works by blocking nerve impulses to the muscles to reduce involuntary muscle contractions.
Zanaflex is available in both a tablet and capsule form. The capsule form has been shown to work more quickly than the tablet, so a Zanaflex or generic tizanidine tablet cannot be substituted for a Zanaflex capsule. This medication should only be used under the guidance of a healthcare provider.
Zanaflex is sometimes prescribed off-label to treat symptoms of fibromyalgia.
Common side effects of Zanaflex include, but are not limited to, drowsiness, dizziness, dry mouth, weakness, constipation, and nervousness. Other possible side effects include urinary tract infection, abnormal liver function tests, speech problems, sore throat, and runny nose.
Serious side effects of Zanaflex may include low blood pressure (hypotension), liver injury, hallucinations, and kidney problems. Consult a healthcare provider if you experience any side effects while using Zanaflex.
Allergic reactions are rare but may present as certain signs and symptoms, such as trouble breathing, hives, and swelling of the face or throat.
This is not a complete list of side effects. Consult your doctor or healthcare professional for additional information and medical advice regarding other possible side effects or drug interactions.
Gerardo Sison, Pharm.D., graduated from the University of Florida. He has worked in both community and hospital settings, providing drug information and medication therapy management services. As a medical writer, he hopes to educate and empower patients to better manage their health and navigate their treatment plans.
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SingleCare is a prescription discount service that offers free coupons on thousands of prescription drugs. It can be used whether you have insurance, Medicare, Medicaid, or none of the above, but it cannot be combined with insurance.
SingleCare provides transparent drug pricing, so you can compare discounts at pharmacies near you. Browse singlecare.com to find drug discounts, helpful information about your prescription, and resources to help you make informed health decisions.
Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
Blog articles are not medical advice. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911.
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© 2025 SingleCare Administrators. All rights reserved