Zoloft Coupons & Prices

Sertraline Hcl

Zoloft is an FDA-approved antidepressant that is used to treat depression and anxiety. It can also be used to treat obsessive-compulsive disorder (OCD), panic disorder, post-traumatic stress disorder (PTSD), and premenstrual dysphoric disorder. Zoloft belongs to a group of medications called selective serotonin reuptake inhibitors (SSRIs). The generic version of Zoloft is sertraline hydrochloride. The cash price of Zoloft is about $543.85 for 30, 50mg tablets. You can use SingleCare Zoloft coupons to potentially save and pay a lower price of $8.72 for 30, 50mg tablets of generic Zoloft.

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Zoloft coupon at Kroger Pharmacy
$11.72
$ 8.72
$3 off with signupwith signup

Show this free card to your pharmacist.

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Zoloft coupon at Harris Teeter Pharmacy
$11.72
$ 8.72
$3 off with signupwith signup

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Zoloft coupon at Walmart Neighborhood Market Pharmacy
$13.89
$ 10.89
$3 off with signupwith signup
Zoloft coupon at Walmart Pharmacy
$13.89
$ 10.89
$3 off with signupwith signup
Zoloft coupon at Food Lion Pharmacy
$ 13.33
Zoloft coupon at Walgreens Pharmacy
$17.78
$ 14.78
$3 off with signupwith signup
$ 18.00
$24.87
$ 21.87
$3 off with signupwith signup
$ 37.00

About SingleCare Pricing

SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.

Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.

Prices updated: 12/05/2025

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About Zoloft

Zoloft is an FDA-approved antidepressant that is used to treat depression and anxiety. It can also be used to treat obsessive-compulsive disorder (OCD), panic disorder, post-traumatic stress disorder (PTSD), and premenstrual dysphoric disorder. Zoloft belongs to a group of medications called selective serotonin reuptake inhibitors (SSRIs). The generic version of Zoloft is sertraline hydrochloride. The cash price of Zoloft is about $543.85 for 30, 50mg tablets. You can use SingleCare Zoloft coupons to potentially save and pay a lower price of $8.72 for 30, 50mg tablets of generic Zoloft.

Zoloft Price History & Information

Price History for Zoloft (Brand) & Sertraline Hcl (Generic)

30 count, tablet, 50mg

Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.

Average 1-Month Prices for Zoloft (Brand) & Sertraline Hcl (Generic)

30 count, tablet, 50mg
PharmacyZoloft Retail PriceSertraline Hcl Retail PriceSertraline Hcl SingleCare Price
CVS Pharmacy$528.90$34.95$33.86
Walmart$520.50$14.10$13.80
Walgreens$533.10$39.90$28.49
Kroger Pharmacy$550.50$33.72$11.20
Albertsons Pharmacy-$61.90$14.29

These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.

About Zoloft

Zoloft is an FDA-approved antidepressant that is used to treat depression and anxiety. It can also be used to treat obsessive-compulsive disorder (OCD), panic disorder, post-traumatic stress disorder (PTSD), and premenstrual dysphoric disorder. Zoloft belongs to a group of medications called selective serotonin reuptake inhibitors (SSRIs). The generic version of Zoloft is sertraline hydrochloride. The cash price of Zoloft is about $543.85 for 30, 50mg tablets. You can use SingleCare Zoloft coupons to potentially save and pay a lower price of $8.72 for 30, 50mg tablets of generic Zoloft.

Zoloft FAQs

Medically reviewed by Gerardo SisonPharm.D.
Licensed Pharmacist

How much does Zoloft cost without insurance?

Without insurance, the retail price of Zoloft is around $543.85 for 30, 50mg tablets. You can use a free SingleCare savings card or Zoloft coupon and pay as little as $8.72 for 30, 50mg tablets of generic Zoloft at local pharmacies like CVS Pharmacy, Walmart, and Walgreens. You can also ask your pharmacist about sertraline, the generic version of Zoloft, which may be cheaper than the brand name.

How much does Zoloft cost with insurance?

You can ask your pharmacist to calculate your Zoloft price with insurance since copays vary by health insurance plan. With SingleCare, Zoloft may cost just $8.72 for 30, 50mg tablets of generic Zoloft, which could be more affordable than your insurance. Use a SingleCare Zoloft coupon during your next visit to your local pharmacy and compare pricing.

Does Medicare cover Zoloft and how much does it cost?

Medicare does not typically cover branded Zoloft, but you can use a SingleCare discount card to save on this expensive prescription drug. With SingleCare, you could pay as little as $8.72 for 30, 50mg tablets of generic Zoloft. Savings can be redeemed at participating pharmacies across the United States.

Is there a generic of Zoloft?

Zoloft is the brand-name prescription drug. Sertraline hydrochloride is the generic version of Zoloft.

What is Zoloft?

Zoloft is an FDA-approved antidepressant medication used to treat major depressive disorder (MDD), obsessive compulsive disorder (OCD), premenstrual dysphoric disorder (PMDD), panic attacks, post-traumatic stress disorder (PTSD), and social anxiety disorder. It belongs to a group of medicines called selective serotonin reuptake inhibitors (SSRIs). Sertraline hydrochloride is the generic version of Zoloft. Zoloft works by increasing the amount of serotonin in the brain, which can help regulate mood and improve feelings of well-being.

What doses of Zoloft are available?

Zoloft is available as an oral tablet and a liquid solution. Oral tablets come in strengths of 25 mg, 50 mg, and 100 mg. The oral solution comes in a strength of 20 mg/mL. Zoloft is usually taken once daily; however, it should only be used as directed by your doctor.

Do not take Zoloft within 14 days before or after you use an MAO inhibitor, as a dangerous drug interaction could take place. You should consult with your doctor if you are or plan to become pregnant while taking Zoloft. Also ask a healthcare provider before taking Zoloft while breastfeeding.

Zoloft should not be prescribed to those younger than 18 years old without the medical advice of a doctor. Tell your doctor about other medical conditions you may have, such as heart disease, liver or kidney disease, high blood pressure, seizures, or bleeding problems before taking Zoloft. Consult your doctor if you have a history of bipolar disorder as the use of Zoloft could increase the risk of mania or hypomania. 

What are the side effects of Zoloft?

The use of Zoloft has been linked to side effects such as nausea, indigestion, diarrhea, decreased appetite, and tremors. Other side effects of Zoloft include increased sweating, ejaculation problems, and decreased libido. This may not be a complete list of side effects.

You should seek medical attention right away if you experience blurred vision, seizures, manic episodes, or symptoms of low sodium levels in the body, such as confusion, weakness, and unsteadiness. You should also seek immediate medical attention if you experience an allergic reaction such as hives, swelling of the face, lips, and mouth, or trouble breathing.

Talk to your pharmacist or healthcare professional about other possible risks and benefits associated with Zoloft before starting treatment.

Medically reviewed by Gerardo SisonPharm.D.
Licensed Pharmacist

Gerardo Sison, Pharm.D., graduated from the University of Florida. He has worked in both community and hospital settings, providing drug information and medication therapy management services. As a medical writer, he hopes to educate and empower patients to better manage their health and navigate their treatment plans.

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Where are Zoloft coupons from SingleCare accepted?

SingleCare is accepted at most national pharmacies and grocers, including the following:

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