Key takeaways
Ajovy is a brand-name injectable medication used to prevent migraines.
Ajovy can cost about $12,000 per year without insurance.
Insurance may cover Ajovy, but coverage varies, and patients might face high copays or need prior authorization.
Without insurance, patients can reduce the cost using a SingleCare discount card, saving approximately $350 off the monthly retail price.
Other alternatives include enrolling in patient assistance programs, price shopping, or consulting a healthcare professional about switching to a more affordable treatment.
Ajovy is a brand-name prescription drug used to reduce the incidence and severity of migraine headaches. The active ingredient, fremanezumab-vfrm, is a monoclonal antibody that prevents the tightening of blood vessels in the head, the primary cause of migraine pain. Ajovy can be an expensive brand-name drug. It has no generic equivalent. There are ways, however, to make Ajovy affordable even without health insurance.
How much does Ajovy cost without insurance?
People without insurance coverage for Ajovy will pay an average retail price of $1,021 for a 225 mg auto-injector, enough medicine for a single monthly dose. A year of treatment could add up to over $12,000 per year.
For individuals without insurance or those who are denied coverage, alternatives may be available, including other FDA-approved drugs that work similarly to Ajovy, known as CGRP inhibitors. These include monoclonal antibody injections similar to Ajovy, such as Aimovig (erenumab), Vyepti (eptinezumab), and Emgality (galcanezumab). Unfortunately, these other CGRP antagonists are as expensive or more expensive than Ajovy.
While over-the-counter medications and supplements may partly relieve migraine symptoms, they are not effective as preventive treatments like Ajovy or other prescription drugs.
| Compare Ajovy prices to related drugs | |||
|---|---|---|---|
| Drug name | Price without insurance | SingleCare price | Savings options |
| Ajovy (fremanezumab) | $1,019 for 1, 1.5 mL of 225 mg/1.5 mL solution injection pen | $653 for 1, 1.5 mL of 225 mg/1.5 mL solution prefilled syringe of brand-name Ajovy at Kroger | See latest prices |
| Vyepti (eptinezumab) | $9,367 for 3, 1 mL of 100 mg/1 mL vials | $5,694 for 3, 1 mL of 100 mg/1 mL vials of brand-name Vyepti at Kroger | See latest prices |
| Emgality (galcanezumab) | $994 for 1, 1 mL of 120 mg/mL solution injection pen | $605 for 1, 1 mL of 120 mg/mL solution injection pen of brand-name Emgality at Kroger | See latest prices |
| Aimovig
(erenumab) |
$1,039 for 1, 1 mL of 140 mg/1 mL solution injection pen | $753 for 1, 1 mL of 140 mg/1 mL solution injection pen at Kroger | See latest prices |
| Nurtec | $1,376 for 8 tablets | $870.42 for 8 tablets at Walgreens | See latest prices |
Prescription drug prices often change. These are the most accurate medication prices available at the time of publication in ZIP code 23666 as of December 1, 2025. The listed price, without insurance, refers to the price of brand-name drugs (unless otherwise specified). The listed SingleCare price references the price of generic drugs if available. Click the link under “Savings options” to see the latest drug prices.
Is Ajovy covered by insurance?
Most insurance companies cover Ajovy prescriptions, but they may require prior authorization or that other drugs be tried first. People with Medicare Part D coverage are less likely to have coverage for Ajovy. Medicaid coverage varies by state. Some states do not cover Ajovy. Those that do typically require prior authorization and step therapy.
Health insurance can help, but the out-of-pocket cost is hard to predict. Ajovy is typically classified in the highest copay tiers and therefore has a high copay cost. There may also be deductibles or coinsurance costs that need to be met.
How to get Ajovy covered by insurance
When Ajovy coverage is denied, the most likely reason is that requirements for coverage have not been met. Due to its expense, prior authorization and step therapy are often required before approval. Other medications must be tried and fail first before insurance will cover the cost of Ajovy. These step therapy requirements vary by insurance provider. The most efficient way to find out is to talk to an insurance representative.
In some cases, Ajovy may not be covered by the insurance plan. Talk to the prescriber. It’s possible to file a formulary exception to get it covered. The prescriber will need to submit a letter of medical necessity as well as a history of the drugs and other migraine treatments that have already been tried.
How to get Ajovy without insurance
Patients without health insurance or those who have been denied coverage may be eligible to enroll in Teva’s patient assistance program. Unfortunately, not everyone will qualify for financial assistance. Here are other ways to make Ajovy treatment more affordable.
1. Start by using a SingleCare discount card
A SingleCare savings card can immediately reduce the cost of a monthly Ajovy injection to
$653 at participating pharmacies, a savings of about $350 off the average retail price. Over a year, those monthly savings could add up to over $4,000. On the Ajovy coupon page, also read the FAQs section for more information on additional savings. Make sure to sign up for SingleCare’s bonus loyalty program. Simply by using SingleCare drug coupons, you can earn additional savings on refills and future drug purchases.
2. Compare pharmacy prices
Another solution is to find the pharmacy with the lowest price for Ajovy. When using SingleCare’s savings program, the lowest price you find might save hundreds of dollars off the average cash price.
3. Consider switching to other treatments
Consult your healthcare provider for personalized medical advice on more affordable migraine prevention treatments. Many are available as generic drugs. Keep in mind that they may differ in their effectiveness and possible side effects, but for many people, they help prevent migraines.
- Ajovy HCP, Teva Pharmaceuticals