Key takeaways
Jublia is a topical treatment for fungal toenail infections, and it is currently only available as a brand-name medication.
The Jublia cost without insurance is over $1,000 for one 4 mL bottle, but how long that bottle lasts will vary depending on how many toenails need treatment.
If Jublia is too expensive, consider enrolling in the manufacturer’s patient assistance programs, using a SingleCare Jublia coupon, or switching to a generic alternative.
Jublia (efinaconazole) is a brand-name prescription antifungal drug that’s approved by the Food and Drug Administration (FDA) to treat fungal toenail infections (onychomycosis). It’s a topical medication applied to the affected toenails and surrounding skin for 48 weeks. It’s also one of a handful of effective topical therapies for toenail fungus, but it comes at a cost because there are no generic versions. Without insurance, the Jublia cost can exceed $1,000 per month, and even more if several toenails are affected.
RELATED: What is Jublia?
How much does Jublia cost without insurance?
Without health insurance coverage, a single applicator bottle containing 4 mL of Jublia 10% solution costs about $1,060 at the full cash price. How long that bottle lasts depends on how many toenails are affected and how well the medicine is applied. If 4 mL is enough for a 30-day supply, one year of Jublia treatment will cost around $12,000 without insurance.
RELATED: Jublia dosage, forms, and strengths
Compare Jublia prices to related drugs |
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|---|---|---|---|
| Drug name | Price without insurance of brand-name drug | SingleCare price | Savings options |
| Jublia (efinaconazole) | $1,060 for 4 mL of 10% solution | $727 for 4 mL of 10% solution of brand-name Jublia at Kroger or Harris Teeter | See latest prices |
| Ciclopirox | $154 for 6.6 mL of 8% solution | $17 for 6.6 mL of 8% solution of generic ciclopirox at Kroger or Harris Teeter | See latest prices |
| Tavaborole | $1,357 for 10 mL of 5% solution | $39 for 10 mL of 5% solution of generic tavaborole at CVS Pharmacy | See latest prices |
| Terbinafine | $260 for 30, 250 mg tablets | $11 for 30, 250 mg tablets of generic terbinafine at Walmart | See latest prices |
What is the generic for Jublia?
There is no generic for Jublia. Jublia is only available as a brand-name drug. Topical efinaconazole, the active ingredient, may not have a generic version until 2035 due to its patent.
Jublia alternatives
There are alternatives to Jublia that may be more affordable. Mild to moderate toenail fungus is typically treated with prescription topical medications, like ciclopirox or tavaborole. For more severe cases of toenail fungus, oral antifungals may be prescribed.
Oral antifungals are the most effective nail fungus treatments, but they have a higher risk of side effects than topicals. Terbinafine is an example of a highly effective oral antifungal. The cost is about $260 for 30, 250 mg tablets, and one tablet must be taken daily for 12 weeks to treat a toenail fungal infection. Terbinafine can remain in the nail for up to 30 weeks after treatment is complete.
Topical antifungals are often less effective than oral antifungals for toenail fungus because of the thickness of the toenail. However, Jublia has a high cure rate due to its ability to penetrate the nail effectively, but it may be expensive since it is only available as a brand-name medication. Generic topical treatment alternatives include tavaborole and ciclopirox.
Is Jublia covered by insurance?
Insurance coverage for a Jublia prescription is spotty. Some health insurance and Medicare Part D drug plans provide coverage for Jublia, but many do not. If they do provide coverage, they may require healthcare providers to complete a prior authorization form before they consider approving it. Most insurance plans place Jublia in higher copay tiers, so the out-of-pocket cost may be higher than other toenail fungus prescription medications. Medicaid coverage for Jublia varies by state and plan.
How to get Jublia without insurance
If you have health insurance but your policy doesn’t cover Jublia, you may be able to get a discount through the manufacturer’s Rx Access Program. However, there are restrictions, and you’re ineligible if you don’t have commercial coverage. There are other ways to save, though.
1. Get Jublia discounts with a SingleCare savings card
Instant discount prices on brand-name prescription drugs are available at participating pharmacies through SingleCare. For Jublia, visit SingleCare’s Jublia coupon page or use the SingleCare app to find available discounts near you. SingleCare’s lowest price for a 4 mL Jublia bottle is $727. SingleCare is free to use and available to everyone. Registered members can save even more, and it’s fast and free to sign up.
2. Ask your healthcare provider about generic terbinafine
Nail fungus can sometimes be challenging to treat, so healthcare providers may turn to established, more effective treatments like systemic (oral) antifungals. Terbinafine pills have a very high success rate at curing toenail fungus. The three-month regimen will cost about $780 at full retail price, several thousand dollars less than the 11-month Jublia regimen. Side effects and drug interactions could be a problem, so get medical advice from a healthcare provider before starting terbinafine.
4. Ask your healthcare provider about topical options
If taking an antifungal pill is not an option, ask your healthcare provider about using topical tavaborole or ciclopirox. These drugs have generally shown lower complete cure rates than Jublia, but they are significantly less expensive.
The SingleCare prices in this article are the most accurate at the time of publishing in ZIP code 23666 as of Oct. 2, 2026. Prices vary by pharmacy. Visit our coupon page for updated drug prices at pharmacies near you.
- Jublia efinaconazole solution prescribing information, DailyMed (NIH National Library of Medicine) (2025)
- Jublia patent expiration, Pharsight (2026)
- Onychomycosis, StatPearls (2025)
- Terbinafine hydrochloride tablet prescribing information, DailyMed (NIH National Library of Medicine) (2023)
- A week of oral terbinafine pulse regimen every three months to treat all dermatophyte onychomycosis, Journal of Fungi (2019)
- Recent advances in therapies for onychomycosis and its management, F1000 Research (2019)
- Onychomycosis: an updated review, Inflammation & Allergy-Drug Targets (2020)
- Onychomycosis: a review of new and emerging topical and device-based treatments, Journal of Clinical and Aesthetic Dermatology (2019)
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