Key takeaways
Ezetimibe (Zetia) is an FDA-approved generic medication to lower high cholesterol levels.
Ezetimibe is usually taken long-term. Without insurance, the average annual cost of treatment is around $3,400.
Fortunately, there are many ways to lower the cost of an ezetimibe prescription, such as using a SingleCare discount card, switching to a lower-cost alternative, and shopping around at different pharmacies.
Ezetimibe, the generic form of Zetia, is an FDA-approved prescription medication used to lower high cholesterol, including low-density lipoprotein (LDL) cholesterol. Without insurance, the average ezetimibe price is $849 for 90, 10 mg tablets, a 90-day supply. However, there are several ways to lower the price of an ezetimibe prescription.
Save up to 80% on Ezetimibe with SingleCare
Different pharmacies offer different prices for the same medication. SingleCare helps find the best price for you.
RELATED: What is ezetimibe?
How much does ezetimibe cost without insurance?
The average cost of ezetimibe is $849 for 90, 10 mg oral tablets. At a daily dose of one tablet, this works out to about $3,400 annually for treatment.
Keep in mind, the price may vary depending on the quantity prescribed and the pharmacy. If you have health insurance, your out-of-pocket cost, such as your copay, can vary depending on your plan. Contact your insurance company to learn more about your coverage.
There are also alternatives to ezetimibe. Other cholesterol-lowering medications, including generic statins, may cost less. However, not every alternative is appropriate for everyone. A healthcare professional can help determine which medications may be suitable, and a pharmacist can help you compare their costs.
How much does brand-name ezetimibe cost?
Ezetimibe is the generic version of Zetia. If you don’t have insurance, the average Zetia price is $1,574 for 90, 10 mg tablets. A SingleCare coupon can lower the price of generic ezetimibe to about $14 for 90, 10 mg tablets.
Compare ezetimibe prices to related drugs |
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|---|---|---|---|
| Drug name | Price without insurance | SingleCare price | Savings options |
| Ezetimibe | $849 for 90, 10 mg tablets | $14 for 90, 10 mg tablets of generic ezetimibe at Kroger | See latest prices |
| Lipitor (atorvastatin) | $707 for 30, 40 mg tablets | $8 for 30, 40 mg tablets of generic Lipitor at Kroger | See latest prices |
| Crestor (rosuvastatin) | $1,038 for 90, 20 mg tablets | $14 for 90, 20 mg tablets of generic Crestor at Food Lion | See latest prices |
| Zocor (simvastatin) | $1,035 for 90, 20 mg tablets | $7 for 90, 20 mg tablets of generic Zocor at Kroger | See latest prices |
| Welchol (colesevelam) | $1,116 for 180, 625 mg tablets | $43 for 180, 625 mg tablets of generic Welchol at CVS Pharmacy | See latest prices |
| Questran (cholestyramine) | $449 for 1 box, 60 packets | $49 for 1 box, 60 packets of generic Questran at CVS Pharmacy | See latest prices |
Is ezetimibe covered by insurance?
Commercial health insurance plans may cover ezetimibe, but coverage and out-of-pocket costs vary by plan. Medicare Part D plans may also cover ezetimibe depending on the plan’s formulary. Medicaid coverage and costs can vary by state. Check with your insurance provider for details about your coverage.
How to get ezetimibe without insurance
Ezetimibe is often taken long-term, so prescription costs can add up over time. Fortunately, there are several ways to avoid paying full price for ezetimibe. Here are four ways to save:
1. Use a SingleCare prescription discount card
A SingleCare coupon can lower the ezetimibe price to about $14 for 90, 10 mg tablets, compared with the average retail price of $849. SingleCare is free to use and available to anyone in the U.S. with a valid prescription. Signing up is optional and free, and registered members can unlock additional savings when they sign up.
2. Consider a lower-cost alternative
Ezetimibe is one of several cholesterol-lowering medications. Other medications, including atorvastatin, rosuvastatin, and cholestyramine, may cost less. However, these drugs work differently and may not be appropriate alternatives for everyone. Consult your healthcare provider about which treatment options may be suitable for you. A pharmacist can also help you compare the costs of different medications.
3. Compare the prices at different pharmacies
Pharmacies can charge different prices for the same medication. To find the lowest price, compare ezetimibe prices at local retail, community, and independent pharmacies.
4. Consider Medicare or Medicaid
If you qualify, Medicaid or Medicare Extra Help may help reduce your prescription costs. Medicare Extra Help assists eligible people with Medicare Part D costs, while Medicaid coverage and out-of-pocket costs vary by state. Visit Medicare.gov or your state’s Medicaid website to learn about eligibility requirements and how to apply.
RELATED: Cholesterol medication coupons & resources
The SingleCare prices in this article are the most accurate at the time of publishing in ZIP code 23666 as of Sep. 14, 2026. Prices vary by pharmacy. Visit our coupon page for updated drug prices at pharmacies near you.
- Ezetimibe tablets prescribing information, DailyMed (NIH National Library of Medicine) (2025)
- Help with drug costs, Centers for Medicare & Medicaid Services (2026)
- Medically accurate: SingleCare’s Medical Review Board analyzes all of our content to confirm it’s in line with current medical advice.
- Evidence-based: Our content is sourced from reputable U.S.-based healthcare professionals and peer-reviewed research.
- Trustworthy: All of SingleCare’s content goes through a multi-phase review process by our writers, editors, and Medical Board in order to provide clear and credible information.