What is the average cost of a 30-day supply of Eliquis?

In this article:

• Average monthly cost of Eliquis
• Ways to lower Eliquis cost per month

In this article

• Average monthly cost of Eliquis
• Ways to lower Eliquis cost per month

Eliquis is a brand-name prescription drug used to prevent and treat blood clots. It is a blood thinner usually prescribed for people with medical conditions such as atrial fibrillation (abnormal heart rhythm), deep vein thrombosis (DVT, or a blood clot in the deep veins, usually of the legs), and pulmonary embolism (PE, or a blood clot in the lungs).

Typically, the average retail price of Eliquis is $830 for a monthly supply of 60, 5 mg tablets, but there are ways to lower the cost, such as using SingleCare coupons or the manufacturer’s patient assistance programs.

Average monthly cost of Eliquis

The average monthly cost of Eliquis is $830 for a 30-day prescription of 60, 5 mg tablets. Its generic version (apixaban) was approved by the United States Food and Drug Administration (FDA) in 2019; however, it likely won’t be available on the market until at least 2028. 

This is because the manufacturer of Eliquis, Bristol-Myers Squibb Co., obtained a court ruling granting it the sole right to the prescription medication and preventing all generic versions from entering the market until the patent protection expires in 2028.

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Eliquis 5 mg (60 Tablet)

23666 - Hampton, VA

$487.86

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$487.86

i Price with signup

Get free coupon

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Several factors influence the cost of your medication. This includes market competition, for instance, in the case of Eliquis, where a generic drug is unavailable, the manufacturer has the monopoly to set a price that yields the largest profit.

The research and development costs are also considered when setting the list price of a medication. Drug development comes with high costs and is often lengthy (over 10 years). It can cost over 2 billion for a drug to be approved for use. Therefore, pharmaceutical companies often set the cost of medication to cover their expenses during the clinical trial phase of the drug development. Other factors that influence drug prices include quantity, insurance, and reimbursement.

The good news is that Eliquis is typically covered by commercial insurance plans, including Medicare Part D plans and Medicaid. “Regarding cost and insurance coverage, most insurance plans cover Eliquis use, but copays may differ widely,” says Gail Clifford, M.D, and medical consultant at ARRC LED.

The cost of Eliquis for Medicare beneficiaries varies depending on a person’s condition. If you are prescribed Eliquis for DVT/PE, you may pay an average of $44 monthly, while people with atrial fibrillation (not due to a heart valve problem) may pay $54 monthly. This varies by health plan; therefore, contact your insurance provider for more information about your prescription drug coverage.

People who are uninsured can use manufacturers’ patient assistance programs and other available discounts to reduce out-of-pocket costs.

Ways to lower Eliquis cost per month 

Prescription drugs like Eliquis might be expensive for the average person to cover out of pocket. If this is you, here are six ways to lower the cost of Eliquis:

1. Use the SingleCare discount card

Without insurance, the average cost of Eliquis is $830 for a 30-day supply of 60, 5 mg tablets. With the SingleCare discount card, you may be able to get a lower price of $488 for the same quantity and dosage of Eliquis at Kroger. The SingleCare discount card is free to use in over 35,000 pharmacies nationwide and in Puerto Rico.

2. Check for patient assistant programs

Drug companies Bristol-Myers Squibb and Pfizer, through their patient assistance program, Eliquis 360 Support, offer a 40% discount or more on Eliquis prescriptions.

“I also advise patients to use patient assistance programs offered by the manufacturer, such as Bristol Myers Squibb or Pfizer, and other third-party organizations that offer copay cards or assistance programs to help reduce out-of-pocket costs for the patient,” Dr. Clifford says.

3. Go for cheaper alternatives

“While Eliquis doesn’t currently have a generic equivalent, I advise patients to discuss lower-cost alternatives, like warfarin, with their healthcare provider to determine whether it’s appropriate for them,” says Whitney Prude, Pharm.D., BCACP, clinical pharmacist and nationally certified health and wellness coach, based in Rochester, Minnesota.

For example, the average retail price of warfarin is $29 for 30, 5 mg tablets, which is lower than the $830 cost of Eliquis. You can even get it for as low as $4 (for 30, 5 mg generic warfarin tablets) with the SingleCare discount card.

4. Shop around

“It’s also worth calling a few local pharmacies since cash prices can vary widely [and find the lowest price], and some pharmacies have their own discount programs,” Dr. Prude says.

5. Apply for the “Extra Help” program

Extra Help is a Medicare program that helps low-income beneficiaries pay for their prescription drug costs. According to their website, they pay “Medicare drug coverage (Part D) premiums, deductibles, coinsurance, and other costs.” You can apply for the Extra Help program on their website. Usually, you’re automatically enrolled in Extra Help if you receive full Medicaid coverage, get Supplemental Security Income (SSI), or receive help from the state to pay for Part B premiums. 

6. Use the Eliquis savings card

The manufacturers also offer a copay card for eligible patients to help them save on Eliquis. Patients who are prescribed Eliquis and use the copay card pay as little as $10 for a 30-day supply (up to 74 tablets for the first fill and up to 60 tablets for subsequent refills) at select pharmacies for up to two years. The maximum annual benefit with the copay card is $6,400.

The SingleCare prices in this article are the most accurate at the time of publishing in ZIP code 23666 as of October 23, 2025. Prices vary by pharmacy. Visit our Eliquis coupon page for updated Eliquis prices near you.