Key takeaways
Humira is a biologic TNF blocker often prescribed to treat rheumatoid arthritis, Crohn’s disease, plaque psoriasis, and other inflammatory diseases.
Without insurance or discounts, Humira can cost close to $9,000 per month.
You can save on Humira by applying for a Humira savings card, using a Humira coupon from SingleCare, considering biosimilars, and looking into government assistance programs.
Humira (adalimumab) is a brand-name drug prescribed for a range of inflammatory health conditions, including moderate to severe rheumatoid arthritis, Crohn’s disease, plaque psoriasis, psoriatic arthritis, hidradenitis suppurativa, ankylosing spondylitis, and ulcerative colitis. Since it’s a specialty drug, it can be pricey, costing close to $9,000 per month. But there are resources that can drastically reduce that price.
How much does Humira cost without insurance?
The retail cost of Humira is about $8,983 for two auto-injector kits, a 30-day supply. That’s the average cost without insurance, which varies by pharmacy and location.
“The cost of Humira can vary significantly based on factors such as dosage, frequency of administration, and the pharmacy dispensing the medication,” according to Sean Ormond, MD, founder of Atlas Pain Specialists.
8 ways to save on Humira
Getting the best price on Humira may require a little research to ensure you’re saving as much as possible. Here are eight of the best ways to save on Humira.
1. Use a Humira coupon from SingleCare
SingleCare negotiates directly with pharmacies to get members discounts at over 35,000 locations across the U.S. For example, a SingleCare coupon for Humira can knock close to $3,000 off Humira’s monthly price, lowering it from $8,983 to $6,042.
SingleCare is free to use, with no sign-up required. Members who sign up save even more. Just present your SingleCare card or free Humira coupon at a local participating pharmacy for instant savings. You’re eligible for SingleCare discounts even if you have Medicare or private health insurance, but you can’t combine SingleCare discounts with insurance.
RELATED: How does SingleCare work?
2. Humira patient assistance
People who are unemployed or underinsured may qualify for the AbbVie Patient Assistance Program. This program provides no-cost assistance to those who meet certain income criteria. Visit myAbbVie Assist to see if you qualify for free Humira.
3. Humira savings card
AbbVie’s patient assistance applies primarily to uninsured patients, but its Humira Complete Savings Card can help people with health insurance save as well. Eligible patients must have health insurance that covers only part of Humira’s cost, and they cannot receive assistance from any government-sponsored program, such as Medicare, Medicaid, TRICARE, or VA programs.
If AbbVie approves your application, you will be sent a discount card to present at your local pharmacy. Not every pharmacy accepts them, though. The maximum annual benefit is $14,000. Any amount you pay using the Humira Complete Savings Card will not count toward your deductible or other out-of-pocket cost-sharing limitations.
4. Humira rebates
Sometimes a pharmacy won’t accept the Humira Complete Savings Card, which could leave you with a hefty bill. If this happens, you may still be able to get Humira at a lower cost by using the Humira Complete Prescription Rebate. Rebates are available only to people with commercial prescription coverage or self-insured plans. Call 800-4HUMIRA (800-448-6472) to see if this option is right for you.
5. Ask your healthcare provider for assistance
Not only can healthcare providers provide individualized medical advice, but they’re also some of the best resources for advice on how to reduce the cost of prescriptions. Dr. Ormond encourages patients to discuss their financial concerns regarding Humira openly with their healthcare provider, who may be able to provide guidance on cost-saving strategies or alternative treatment options.
6. Ask about Humira alternatives
There are several Humira alternatives you can discuss with your healthcare provider, and they may have better insurance coverage, depending on your policy, or be more affordable. Examples include Amjevita, Cyltezo, Hyrimoz, and Hadlima.
RELATED: Cyltezo vs. Humira
7. Look into government assistance programs
People with a Medicare Part D plan and financial difficulties can consider the federal Medicare Extra Help program, a state-sponsored assistance program, or both. Eligible applicants for Extra Help must meet income and resource limits. For state-sponsored assistance programs, each state has different requirements for pharmaceutical assistance, so the application process depends on where you live.
8. Compare prices
In a recent survey, Consumer Reports discovered that drug prices can vary by hundreds of dollars between pharmacies, even ones in the same city. So, making an effort to find the best prices might lead to significant savings on Humira. You can use the SingleCare website or app to compare prices at pharmacies near you.
Is there a generic Humira?
Oftentimes, there will be generic versions of brand-name medications that are more affordable for consumers. There’s no “generic Humira,” per se, because it is a biologic drug, and biologics have biosimilar versions, not generic versions. But there are Humira biosimilars that may be more affordable. Biosimilars must be given the same way, have the same strength and dosage forms, and have the same potential side effects as the original biologic.
The following Humira biosimilars are now available in the U.S.:
- Amjevita (adalimumab -atto)
- Abrilada (adalimumab-afzb)
- Cyltezo (adalimumab-adbm)
- Hadlima (adalimumab-bwwd)
- Hulio (adalimumab-fkjp)
- Hyrimoz (adalimumab-adaz)
- Idacio (adalimumab-aacf)
- Simlandi (adalimumab-ryvk)
- Yusimry (adalimumab-aqvh)
- Yuflyma (adalimumab-aaty)
“The appropriate [biosimilar] to prescribe depends on the patient’s unique situation and other factors such as medical history, duration of the condition, severity of the condition, past medical treatments, and treatment goals,” says Anna H. Chacon, MD, a U.S. board-certified dermatologist based in South Florida.
Does insurance cover Humira?
“Many insurance plans cover Humira, but coverage details can vary widely depending on the specific plan and the medical condition being treated,” Dr. Ormond says. “Plus, prior authorization may be required by some insurance plans before they will cover Humira. This involves the healthcare provider demonstrating the medical necessity of the medication.” You may also need to prove that you tried a less expensive medication first, which is called step therapy.
Every plan has its own set of terms, so it’s important to check the details and consult a healthcare provider when considering Humira.
RELATED: Does Blue Cross cover Humira?
Does Medicare cover Humira?
“Humira is usually covered under Medicare Part D,” says Supriya Rao, MD, a board-certified physician in internal medicine, gastroenterology, obesity medicine, and lifestyle medicine. However, “the extent of coverage depends on what plan you are enrolled in.” These plans are either bundled with a Medicare Advantage (Part C) plan or offered as a stand-alone Part D add-on to Medicare Part A or Part B plans.
However, like private insurance, each plan is different, and its copays and deductibles can vary. Check the plan’s formulary or contact a plan representative for coverage details.
Does Medicaid cover Humira?
Medicaid is a program that receives funding from both the federal and state governments to provide extra assistance for low-income Americans. Medicaid coverage for Humira varies by state of residence. According to the Humira website, Medicaid beneficiaries with Humira coverage pay $8 or less per month for Humira, depending on their state of residence.
Why is Humira so expensive?
Humira’s high average price comes primarily from the complicated process required to make it. Manufacturers make most drugs by mixing synthetic chemicals together. However, Humira is a biologic drug, which is “derived from living cells, which makes their creation more complex and costly,” according to Dr. Rao. “A lot goes into the research and development of biologics, which drives the prices up that the consumer sees.”
Humira belongs to a class of medications called tumor necrosis factor (TNF) blockers. “These medications function by inhibiting TNF, a substance in the body that leads to inflammation and related symptoms,” Dr. Rao explains. The drug blocks the TNF protein, reducing its inflammatory effects.
On top of that, developing a new drug is a long, expensive process. A study published in 2020 estimated that the cost of bringing a new drug to market can range from $766 million to $2.8 billion. Not only does the manufacturer have to pay for research and development, but they also have to run clinical trials and submit the medication to the Food and Drug Administration for a drug review, which all costs money.
Bottom line: You don’t have to pay full price for Humira
Humira is an expensive medication, but there are various ways to save, including SingleCare coupons, patient assistance programs, and government resources. Don’t hesitate to discuss your options with your healthcare provider. They’re familiar with ways to save on Humira and alternatives to consider that can help save you money.
The SingleCare prices in this article are the most accurate at the time of publishing in ZIP code 23666 as of March 20, 2026. Prices vary by pharmacy. Visit our Humira coupon page for updated Humira prices near you.
- myAbbVie Assist, AbbVie
- Help with drug costs, Centers for Medicare & Medicaid Services
- State pharmaceutical assistance programs, National Conference of State Legislatures (2022)
- How to pay less for your meds, Consumer Reports (2018)
- Biosimilar basics for patients, Food and Drug Administration (2023)
- Biosimilar product information, Food and Drug Administration (2026)
- Humira cost, AbbVie
- Tumor necrosis factor (TNF) inhibitors, American College of Rheumatology (2025)
- Estimated research and development investment needed to bring a new medicine to market, 2009–2018, JAMA (2020)
- The FDA’s drug review process: Ensuring drugs are safe and effective, Food and Drug Administration (2017)