Key takeaways
Repatha (evolocumab) is an injectable medication used to manage high cholesterol levels and lower the risk of cardiovascular disease. There is no generic version currently available.
Repatha costs an average of $794 for two 140 mg/mL syringes without insurance, but Medicare, Medicaid, and private insurance may cover it with prior authorization.
Ways to save on Repatha without insurance include using a SingleCare Repatha coupon, applying for government health programs, and checking your eligibility for drug manufacturer discounts and programs.
For people with high cholesterol that isn’t well-controlled by statins alone, Repatha (evolocumab) can be a powerful next step. This injectable medication is used to lower low-density lipoprotein (LDL) cholesterol and reduce the risk of having a heart attack and stroke. However, this medication can come with a high price tag, making affordability a concern for many patients. There are ways to save, though, even without insurance.
How much does Repatha cost?
The cost of Repatha depends on the dosage form you’re prescribed, whether it’s the Repatha syringe or the Repatha SureClick autoinjector pen.
Repatha cost comparison |
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|---|---|---|---|
| Dosage form | Average price without insurance | SingleCare price | Repatha coupons |
| Repatha syringe | $794 per 2, 140 mg/mL syringes | $462 per 2, 140 mg/mL syringes at Kroger | Get coupon |
| Repatha SureClick | $758 per 2, 140 mg/mL autoinjector pens | $462 per 2, 140 mg/mL autoinjector pens at Kroger | Get coupon |
Prescription drug prices often change. These are the most accurate medication prices at the time of publishing in zip code 23666 as of 10/20/2025. The listed price without insurance references the price of brand-name drugs (unless otherwise specified). The listed SingleCare price references the price of generic drugs if available. Click the link under “Repatha coupons” to see the latest drug prices.
Cholesterol Medication Coupons & Resources
Does insurance cover Repatha?
According to Repatha’s manufacturer, Amgen, the drug is covered for 98% of people with commercial insurance, 93% of people with Medicaid, and 85% of people with Medicare. However, most people may need to go through extra steps to get coverage. Amgen states that only about 3 in 10 commercial insurance plans don’t require prior authorization for Repatha coverage. For example, UnitedHealthcare’s 2025 Prescription Drug List includes Repatha and Repatha Sureclick, but both forms of the drug require prior authorization and step therapy.
The cost of Repatha can vary by company and specific plan. Under some UnitedHealthcare commercial insurance plans, Repatha is a Tier 2 drug, meaning it can cost more than generic or preferred medications but less than Tier 3 medications. In some Blue Cross and Blue Shield of Texas plans, Repatha is a preferred brand-name medication, and coinsurance is between 30% and 35% of the drug cost.
Most Medicare plans list Repatha in their drug formularies as a preferred brand-name drug, but also require prior authorization for coverage. Amgen states that about 73% of Medicare prescriptions for Repatha cost $50 or less per month. The cost of Repatha on Medicare plans can be as low as $0, but it depends on the specific plan. For example, Aetna’s Medicare Assure in 2025 covers the full cost of Repatha after prior authorization is granted. Some UnitedHealthcare Medicare plans may cover Repatha as a Tier 3 preferred brand-name drug, after prior authorization, which could have a $35 copay per month.
Medicaid may also cover Repatha under certain conditions, but coverage varies by state. For example, Rhode Island’s Medicaid plans offer Repatha coverage with prior authorization. Covered medications on these plans don’t always require a copay, and the drug manufacturer states that about 99% of Medicaid prescriptions cost $10 or less per month.
How to save money on Repatha
If you don’t have insurance coverage for Repatha or your coverage doesn’t fully cover its cost, there are other ways to save.
1. Free Repatha coupons
You can save about $300 per month on Repatha by using a SingleCare prescription discount card or by using the SingleCare app or website to compare Repatha coupons at pharmacies near you. Click on the pharmacy with the lowest price to get your coupon card. You can then save it, text or email it to yourself or a friend, or add it to your digital wallet. Then, show it to the pharmacy staff when you fill your prescription, and they’ll charge you the SingleCare price.
Save up to 80% on Repatha with SingleCare Different pharmacies offer different prices for the same medication. SingleCare helps find the best price for you.
2. Medicare or Medicaid
If you have Medicare or Medicaid, you may be able to significantly reduce your out-of-pocket costs for Repatha.
For those with Medicare Part D, coverage for Repatha varies by plan, but many plans include it on their formularies. If you qualify for the Low Income Subsidy (Extra Help) program, you’ll pay no more than the maximum copay for brand-name drugs, which changes annually. You can apply for Medicare Extra Help through the Social Security Administration’s website.
Most state Medicaid programs also cover Repatha for patients who meet medical necessity criteria. This typically means the drug is prescribed for individuals with very high cholesterol or those who haven’t responded to statin therapy. With Medicaid, copays for covered medications are typically $0 per fill, but they may cost up to $8 in some states.
To find out what you can expect to pay, contact your Medicare Part D provider or state Medicaid office for plan-specific details and to see if you qualify for additional assistance programs.
3. Repatha savings card
Amgen offers a Repatha copay card for people with commercial insurance, which can reduce the out-of-pocket costs to as low as $15 per month. To be eligible, patients taking Repatha must:
- Have a Repatha prescription
- Have commercial or private insurance
- Not receive any benefits from Medicare Part D, Medicaid, or other government programs
- Be a resident of the U.S. or its territories
Like many copay card programs, there can be limits to how much you can save per month and per year. For 2025, the maximum amount you can save is $2,500, which can be helpful for the first few months of taking your medication.
4. Repatha patient assistance program
Amgen offers patient assistance for people who are uninsured and meet specific income requirements. The program is administered through the Amgen Safety Net Foundation, and it can help people get a year’s supply of Repatha for free. To be eligible, patients taking Repatha must:
- Have lived in the United States or its territories for six months or more
- Meet household income thresholds
- Have no insurance coverage
- Not receive any benefits from Medicare’s Extra Help program
The program covers eligible patients for up to 12 months, after which they can reapply.
Is there a cheaper alternative to Repatha?
According to the American College of Cardiology (ACC) and American Heart Association (AHA) 2018 Guideline on the Management of Blood Cholesterol, drugs like Repatha are considered for people with a very high risk of atherosclerotic cardiovascular disease (ASCVD) who have tried a high-intensity statin.
Claire Sullivan, MD, a cardiologist and Clinical Assistant Professor at Case Western Reserve University School of Medicine in Cleveland, Ohio, explains, “Cholesterol medications like statins are first-line medications to lower cholesterol. These are generic and low-cost.” Crestor (rosuvastatin) and Lipitor (atorvastatin) are examples of statin medications that can be prescribed as high-intensity statins.
“Ezetimibe (generic for Zetia) is another generic pill option to lower cholesterol,” Dr. Sullivan says. Ezetimibe can be added to statin therapies for people with a high risk of ASCVD, according to the ACC/AHA guidelines.
Repatha belongs to a class of medications called proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors. Praluent (alirocumab) is another PCSK9 inhibitor, but its cost is similar to Repatha: $711 for two 75 mg/mL autoinjector pens on average without insurance.
A newer alternative to Repatha is Leqvio (inclisiran). “Inclisiran is a twice-a-year shot (after induction shots) of cholesterol-lowering medication that is given in an infusion center,” Dr. Sullivan says. However, she explains that Leqvio is around the same cost as Repatha.
Healthcare providers may also continue recommending lifestyle changes to support healthy cholesterol levels. Krista Kostroman, ND, a naturopathic doctor and Chief Science Officer at The DNA Company, shares, “I often focus on food-based strategies to support cholesterol levels and heart health. This might include a mix of omega-3 fatty acids, insoluble fiber, extra virgin olive oil, and even hibiscus tea. I often recommend foods like fatty fish (such as salmon or sardines) for omega-3s, beans and vegetables for fiber, and using extra virgin olive oil as a staple in cooking. These work together to improve cholesterol, reduce inflammation, and support healthy blood vessels.”
Ultimately, if you’re struggling to afford Repatha or unsure whether it’s the right treatment for you, talk to your healthcare provider. They can walk you through lower-cost alternatives, apply for prior authorization if needed, or help you find the most affordable option based on your health goals and insurance coverage.
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