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Key takeaways
Rybelsus is the only oral tablet formulation within the popular drug class of GLP-1 agonists, which are used for diabetes treatment and weight loss.
Only available as a brand-name medicine, Rybelsus is a significant expense, but cost-saving opportunities exist through coupons, discount cards, and insurance.
Alternative drugs could be considered as a way to avoid the price or side effects of Rybelsus.
Rybelsus (semaglutide) is a prescription medication that controls blood sugar levels in people with Type 2 diabetes. It is not FDA-approved to treat Type 1 diabetes. Since it is also effective for weight reduction, healthcare providers may prescribe it off-label for weight loss purposes. Semaglutide is also the active ingredient in Ozempic (for Type 2 diabetes) and Wegovy (for weight control). Both Ozempic and Wegovy are weekly injections. However, people take Rybelsus as an oral tablet once per day. All three drugs carry a premium price.
Save up to 80% on Rybelsus with SingleCare
Different pharmacies offer different prices for the same medication. SingleCare helps find the best price for you.
Related: Rybelsus side effects
How much does Rybelsus cost without insurance?
Without insurance coverage, the average cash price for 30, 7 mg tablets of Rybelsus is $1,402, about $47 for each tablet. Thirty tablets represent a 30-day supply, so a year’s worth of Rybelsus could run about $17,000.
Rybelsus is a glucagon-like peptide-1 receptor agonist (GLP-1 receptor agonist). Another popular medication in the same drug class is Ozempic, a weekly injection with the same active ingredient as Rybelsus. A 28-day supply of Ozempic 0.25 mg once-weekly injections will cost $1,393, or about $18,000 annually. Other GLP-1 receptor agonist injections cost about the same or more.
If GLP-1 receptor agonist prices are too high, ask the prescribing healthcare provider about other blood glucose-lowering drugs that you haven’t tried yet. Possible candidates include metformin, sulfonylureas, meglitinides, and thiazolidinediones. Other brand-name drugs may be less expensive than Rybelsus, including DPP-4 inhibitors and SGLT2 inhibitors. In some cases, drugs other than Rybelsus may be preferable for people at risk for pancreas problems or thyroid tumors, according to the FDA’s warning on the drug label.
How much does generic Rybelsus cost without insurance?
Semaglutide tablets can only be purchased under the brand name Rybelsus. Generic versions of semaglutide tablets may be available in 2033.
Compare Rybelsus prices to related drugs |
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|---|---|---|---|
| Drug name | Price without insurance of brand-name drug | SingleCare price | Savings options |
| Rybelsus | $1402 per 30, 7 mg tablets | $874 per 30, 7 mg tablets of brand-name Rybelsus at Kroger | See latest prices |
| Ozempic | $1393 per 1, 3 mL of 2 mg/3 mL auto-injector pen | $825 per 1, 3 mL of 2 mg/3 mL auto-injector pen of brand-name Ozempic at CVS | See latest prices |
| Victoza (liraglutide) | $1437 per 3, 3 mL of 18 mg/3 mL auto-injector pens | $92 per 3, 3 mL of 18 mg/3 mL auto-injector pens of generic Victoza at CVS | See latest prices |
| Trulicity (dulaglutide) | $1395 per 4, 0.5 mL of 1.5 mg/0.5 mL auto-injector pens | $776 per 4, 0.5 mL of 1.5 mg/0.5 mL auto-injector pens of brand-name Trulicity at Walgreens | See latest prices |
| Metformin | $138 per 180, 1000 mg tablets | $10 per 180, 1000 mg tablets of generic metformin Kroger | See latest prices |
| Jardiance (empagliflozin) | $860 per 30, 25 mg tablets | $528 per 30, 25 mg tablets of brand-name Jardiance at Kroger | See latest prices |
Prescription drug prices often change. These are the most accurate medication prices at the time of publishing in ZIP code 23666 as of November 8, 2025. The listed price, without insurance, refers to the price of brand-name drugs (unless otherwise specified). The listed SingleCare price references the price of generic drugs if available. Click the link under “Savings options” to see the latest drug prices.
RELATED: Rybelsus alternatives: What can I take instead of Rybelsus?
Is Rybelsus covered by insurance?
People with health insurance, Medicare Part D drug insurance, and military benefits can expect coverage for a Rybelsus prescription as long as it’s used for Type 2 diabetes. There may be hurdles to overcome first. Some insurance plans don’t include Rybelsus in their formulary or require a prior authorization, so check with the insurance company before filling a prescription. Medicaid should cover Rybelsus, but it will vary by state. VA benefits do not currently include Rybelsus in their formulary.
Insurance plans typically place Rybelsus in their mid-tier copay levels, so you can expect to pay a higher copay cost. The final out-of-pocket cost will depend on the policies of other insurance providers, such as deductibles and coinsurance.
How to get Rybelsus without insurance
Getting Rybelsus without insurance can be challenging. Rybelsus prices average around $1,402 per month. The manufacturer, Novo Nordisk, offers a patient assistance program, but only some individuals meet the eligibility requirements. There are other, more reliable options for saving money on Rybelsus. Start with a SingleCare savings card.
1. Use a Rybelsus coupon from SingleCare
With a free coupon from SingleCare, individuals without insurance can save up to $530 off the average retail price of 30 Rybelsus 7 mg tablets. Savings vary by participating pharmacy, so visit SingleCare’s Rybelsus coupons page for the most current information. For additional information, please refer to the FAQs section.
2. Find the lowest price at SingleCare
Comparing prices between pharmacies is another innovative way to save money on prescription drugs. Use SingleCare’s Rybelsus price history table to find the lowest pharmacy price for Rybelsus.
3. Consider switching to other Type 2 diabetes drugs
If price is an issue, consult with your prescriber for medical advice on cheaper diabetes medications or drug combinations that haven’t been tried. Unfortunately, they may not be as effective or have different side effects like hypoglycemia (low blood sugar). However, they may be preferable to Rybelsus, which may have serious side effects like medullary thyroid cancer (MTC) and pancreatitis.
4. Ask about other weight loss drugs
If a healthcare provider has prescribed Rybelsus for weight loss, then uninsured and insured people are in the same boat. Typically, insurers do not cover the cost of Rybelsus in this situation. Again, if other weight management drugs have not been tried, talk to the prescribing medical professional about starting on those drugs first.
5. Get a health insurance policy
When used for Type 2 diabetes treatment, Rybelsus is commonly covered by health insurance, which may be obtainable even if you are unemployed or self-employed. In fact, paying for health insurance may be less expensive than paying out-of-pocket for drugs, supplies, and healthcare provider visits for a chronic illness like diabetes. Start with your state’s health insurance marketplace, but check the plan’s formulary to see if needed drugs, such as Rybelsus, are covered at a reasonable out-of-pocket cost.
6. Enroll in Medicaid
If all else fails, look into Medicaid. If you qualify, Rybelsus or a similar drug can be purchased for only a few dollars per month. Each state outlines eligibility requirements on its Medicaid website, so start there.
6. Buy in bulk
Purchasing a larger quantity can be a path to savings. The price of a 90-day supply of Rybelsus 7 mg tablets with a SingleCare discount is only about $3 less than the cumulative expense of purchasing three sequential 30-day supplies with the discount, but sometimes, the difference can be more substantial.
Expert takeaway
“I generally reserve Rybelsus for patients who are averse to injections; because the price of oral semaglutide is about the same as injectable semaglutide, the efficacy of the oral form is lower, and gastrointestinal side effects are more common with Rybelsus, according to a recent review article,” explains Chad Shaffer, MD, member of the SingleCare Medical Board. “When price is the deciding factor and a GLP-1 agonist is needed, generic liraglutide is hard to beat.”
- Rybelsus drug label, Food and Drug Administration (2017)
- Rybelsus drug patent profile, Drug Patent Watch (2024)
- VA formulary advisor, U.S. Department of Veterans Affairs (2024)
- Comparative effectiveness and safety of oral versus subcutaneous semaglutide in Type 2 diabetes mellitus: A systematic review and meta-analysis, Cureus (2025)