Ambisome (amphotericin B liposomal injection) is an FDA-approved, prescription medication used to treat fungal infections caused by Aspergillus species, Candida species, or Cryptococcus species. It is usually administered as an injection to treat cryptococcal meningitis and visceral leishmaniasis. It can also be used in patients who cannot tolerate or who do not respond to regular amphotericin B treatment. Ambisome is available for use in the form of an intravenous powder for injection. There is currently no generic alternative available. The average retail price of Ambisome is about $324.18. Pay $301.22 for this medication by using a SingleCare Ambisome coupon at participating pharmacies.
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SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
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Prices updated: 12/05/2025
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Ambisome (amphotericin B liposomal injection) is an FDA-approved, prescription medication used to treat fungal infections caused by Aspergillus species, Candida species, or Cryptococcus species. It is usually administered as an injection to treat cryptococcal meningitis and visceral leishmaniasis. It can also be used in patients who cannot tolerate or who do not respond to regular amphotericin B treatment. Ambisome is available for use in the form of an intravenous powder for injection. There is currently no generic alternative available. The average retail price of Ambisome is about $324.18. Pay $301.22 for this medication by using a SingleCare Ambisome coupon at participating pharmacies.
Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.
These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.
Ambisome (amphotericin B liposomal injection) is an FDA-approved, prescription medication used to treat fungal infections caused by Aspergillus species, Candida species, or Cryptococcus species. It is usually administered as an injection to treat cryptococcal meningitis and visceral leishmaniasis. It can also be used in patients who cannot tolerate or who do not respond to regular amphotericin B treatment. Ambisome is available for use in the form of an intravenous powder for injection. There is currently no generic alternative available. The average retail price of Ambisome is about $324.18. Pay $301.22 for this medication by using a SingleCare Ambisome coupon at participating pharmacies.
The average cash price of Ambisome without insurance may be around $324.18 or more. Ambisome is not typically filled at a pharmacy; instead, it is administered in a doctor’s office, hospital, or other healthcare settings by a provider. You may receive Ambisome for $301.22 per 4, 50mg suspension reconstituteds when you use a SingleCare Ambisome prescription discount card. Check with your healthcare provider to see if they will accept a SingleCare discount card.
The cost of Ambisome with insurance may vary based on the type of insurance coverage plan that you are enrolled in. Contact your insurance provider directly to find out exactly how much Ambisome costs under your current insurance plan. SingleCare can help you to easily save on your Ambisome purchases. Pay our lowest price of $301.22 for your Ambisome purchase when you use SingleCare's Ambisome prescription savings card.
Ambisome is not generally covered by Medicare prescription drug plans. Without coverage, the average cash price of Ambisome may be as high as $324.18 for 1, 50mg suspension reconstituted. You can save on this total by using a SingleCare savings card. Redeem automatic savings at participating doctor’s offices, clinics, or hospitals by using your SingleCare savings card and pay $301.22 for your Ambisome prescription.
Ambisome is a brand-name prescription drug manufactured by Astellas Pharma US, Inc. There is currently no generic alternative available.
Ambisome is an FDA-approved prescription medication used to treat fungal infections. It is usually used in patients who cannot tolerate or who do not respond to regular amphotericin treatment. This medication works by damaging the fungal cell membrane and stopping the growth of fungi.
This medication is available in the form of an intravenous powder for injection. It is usually given by infusion into a vein (IV), once daily. This injection is usually injected slowly over two hours. Your doctor will recommend an appropriate dose for you based on an assessment of your current medical condition, other drugs you are currently taking, and your response to treatment.
If you are using this medication at home by yourself, ensure that you learn all preparation and usage instructions from your healthcare professional. Check this product visually for particles or discoloration before use. If either is present, do not use the medication. It may be necessary to continue using this medication for several weeks in order to treat certain fungal infections. Stopping the use of this medication too early may result in a return of the infection.
Common side effects resulting from the use of Ambisome include upset stomach, diarrhea, nausea, vomiting, back pain, chills, chest pain, fast heart rate, headache, trouble sleeping, and sweating. In some cases, your doctor may prescribe other medications such as acetaminophen, diphenhydramine, or hydrocortisone to prevent or relieve side effects related to the infusion. If side effects persist or worsen, tell your doctor or pharmacist right away.
Tell your doctor immediately if you begin to experience serious side effects such as unusual tiredness or weakness, severe stomach pain, or signs of kidney problems, such as decreased urination or blood in the urine, or signs of liver problems, such as yellowing eyes or skin.
This is not a complete list of side effects. Consult your doctor or healthcare professional for additional information and medical advice regarding other possible side effects or drug interactions.
Gerardo Sison, Pharm.D., graduated from the University of Florida. He has worked in both community and hospital settings, providing drug information and medication therapy management services. As a medical writer, he hopes to educate and empower patients to better manage their health and navigate their treatment plans.
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Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
Blog articles are not medical advice. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911.
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© 2025 SingleCare Administrators. All rights reserved