What is Cimduo: Uses, Warnings & Interactions

Updated May 14, 2025  •  Published Dec 30, 2020

Cimduo overview

BRAND NAMES:

  • Temixys, Cimduo

Generic Names:

  • Cimduo

Uses:

  • Treats HIV infection. HIV causes AIDS. This medicine does not cure HIV or AIDS, but combinations of drugs may slow the progress of the disease.

Therapeutic Classes:

  • Antiretroviral Agent

Forms:

  • Tablet

How it’s taken:

  • By mouth

What is Cimduo used for?

What form(s) does Cimduo come in

  • Tablet

What are common Cimduo doses?

  • Tablet 300-300MG

Common Cimduo prescriptions

  • Cimduo
    300-300mg tablet

How to take Cimduo

  • Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

  • Your doctor will tell you how much medicine to use. Do not use more than directed.

  • Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Store the medicine in its original bottle and keep it tightly closed.

  • Do not stop using this medicine without checking first with your doctor. If you stop the medicine even briefly, the virus may become harder to treat. Contact your doctor or pharmacist when your supply is running low so you do not run out.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Store the medicine in its original bottle and keep it tightly closed.

  • Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

  • Do not stop using this medicine without checking first with your doctor. If you stop the medicine even briefly, the virus may become harder to treat. Contact your doctor or pharmacist when your supply is running low so you do not run out.

  • Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

  • Your doctor will tell you how much medicine to use. Do not use more than directed.

What to do if you miss a dose of Cimduo

Cimduo contraindications

  • This medicine is not right for everyone. Do not use if you had an allergic reaction to lamivudine or tenofovir.

Cimduo warnings

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

  • Your immune system may get stronger when you start using HIV medicines. This could cause a hidden infection in your body to become active. Tell your doctor right away if you notice any changes in your health.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

  • Do not breastfeed. You can spread HIV or AIDS to your baby through your breast milk.

  • This medicine may cause the following problems:Lactic acidosis (too much acid in the blood)Liver problemsWorsening of hepatitis B infection (if the medicine is stopped)New or worsening kidney problemPancreatitis (swelling of the pancreas)Lower bone mineral density

  • This medicine will not keep you from giving HIV to others. Always practice safe sex, even if your partner also has HIV. Do not share needles or other items that may have blood or body fluids on them.

  • Tell your doctor if you are pregnant, or if you have kidney disease, liver disease (including hepatitis B or C), or a history of fractures or bone problems (including osteoporosis), or pancreas problems.

Cimduo interactions

  • Some medicines can affect how lamivudine/tenofovir works. Tell your doctor if you are using any of the following:Acyclovir, atazanavir/ritonavir, cidofovir, darunavir/ritonavir, didanosine, ganciclovir, gentamicin, ledipasvir/sofosbuvir, lopinavir/ritonavir, sofosbuvir/velpatasvir, sofosbuvir/velpatasvir/voxilaprevir, sorbitol, trimethoprim, valacyclovir, valganciclovirNSAID or pain reliever medicine

  • Do not take Temixys„¢ together with adefovir.

Cimduo side effects

Serious Side Effects

  • Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes

  • Bone, joint, or muscle pain

  • Fast or troubled breathing, lightheadedness, severe weakness, tiredness, confusion

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Sudden and severe stomach pain, fever

  • Change in how much or how often you urinate, cloudy or bloody urine

Less Serious Side Effects

  • Headache

  • Weight gain around your neck, upper back, breast, or waist

  • Diarrhea