Duavee is a prescription medication used to treat moderate to severe symptoms of menopause, such as hot flashes and vaginal dryness. Duavee is also used to help prevent bone loss after menopause. It works by activating estrogen receptors in certain body tissues while controlling estrogen activity in the uterus to prevent the risk of endometrial cancer. A generic version of Duavee is not yet available. The average Duavee cost is around $264.02 for 30, 0.45-20mg tablets. The lowest SingleCare price for Duavee is $191.61. SingleCare can help you to save on your prescription refill by using a Duavee coupon at participating pharmacies, including but not limited to CVS Pharmacy, Target, Walmart, and Walgreens.
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SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.
Prices updated: 12/05/2025
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Duavee is a prescription medication used to treat moderate to severe symptoms of menopause, such as hot flashes and vaginal dryness. Duavee is also used to help prevent bone loss after menopause. It works by activating estrogen receptors in certain body tissues while controlling estrogen activity in the uterus to prevent the risk of endometrial cancer. A generic version of Duavee is not yet available. The average Duavee cost is around $264.02 for 30, 0.45-20mg tablets. The lowest SingleCare price for Duavee is $191.61. SingleCare can help you to save on your prescription refill by using a Duavee coupon at participating pharmacies, including but not limited to CVS Pharmacy, Target, Walmart, and Walgreens.
Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.
| Pharmacy | Duavee Retail Price | Duavee SingleCare Price |
|---|---|---|
| CVS Pharmacy | $242.10 | $216.90 |
| Walgreens | $264.00 | $217.20 |
| Kroger Pharmacy | $243.60 | $194.70 |
These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.
Duavee is a prescription medication used to treat moderate to severe symptoms of menopause, such as hot flashes and vaginal dryness. Duavee is also used to help prevent bone loss after menopause. It works by activating estrogen receptors in certain body tissues while controlling estrogen activity in the uterus to prevent the risk of endometrial cancer. A generic version of Duavee is not yet available. The average Duavee cost is around $264.02 for 30, 0.45-20mg tablets. The lowest SingleCare price for Duavee is $191.61. SingleCare can help you to save on your prescription refill by using a Duavee coupon at participating pharmacies, including but not limited to CVS Pharmacy, Target, Walmart, and Walgreens.
For patients who find themselves without health insurance coverage, Duavee costs as much as $264.02—if not more. SingleCare may help you save with its free prescription discount card that allows cash-paying customers to pay just $191.61 for their Duavee prescription. You can redeem these drug coupons at SingleCare participating pharmacies every time you pick up a refill.
If you have insurance coverage, your Duavee cost will be based on the type of insurance plan you have. Confirm your exact copay for Duavee with a local pharmacist. Then, compare your copay with insurance to SingleCare's lowest price of $191.61. Our customers have been impressed by how much and how often they can save with SingleCare compared to insurance, Medicare, and manufacturer rebates.
Duavee is typically covered by Medicare, but with a copay of $200 or more in some cases. Use a Duavee coupon above to pay $191.61 for 30, 0.45-20mg tablets. This SingleCare price may even be less than what you'd pay with Medicare. Go to your local pharmacy to compare discounts to ensure you're getting the best deal.
Duavee is a brand-name drug with no generic alternative currently available.
Duavee is an FDA-approved prescription medication used to reduce the symptoms of menopause in women. It contains a combination of conjugated estrogens and a drug known as bazedoxifene. These two components work together in the treatment of menopausal symptoms, such as hot flashes and vaginal dryness, while also preventing bone loss. It works by increasing estrogen levels in the body and also activating the body's receptiveness towards the estrogen hormone as well. Bazedoxifene plays an important role in reducing the risk of uterine cancer or breast cancer caused by using estrogen therapy.
Duavee is available in the form of an oral tablet that is usually taken once daily. It can be taken with or without food as advised by your doctor. Consult with your healthcare provider before using this medication. Your doctor will determine an appropriate dose after considering different factors, such as your current medical condition. It is important to use this medication regularly to get the greatest benefit from it. Do not increase your dosage for this medication beyond what is advised by your doctor.
Regular use of Duavee may lead to side effects such as nausea, diarrhea, indigestion, abdominal pain, dizziness, muscle spasms, and neck pain. Inform your doctor immediately if these symptoms continue or get worse.
This medication may have the potential to cause high blood pressure. You should monitor your blood pressure levels regularly and inform your doctor if the results are too high. Duavee may also, in rare cases, cause serious complications from blood clots, such as heart attacks and strokes. Seek medical attention immediately if you experience any serious side effects such as chest pain, confusion, or coughing up blood.
Duavee should not be taken with other progestins or additional estrogen therapy. Thyroid function may need to be monitored in women who are also taking thyroid medications. The dose of thyroid hormone replacement therapy may need to be increased in women taking Duavee.
This is not a complete list of side effects. You can contact your doctor for medical advice about other side effects and precautions before using this medication.
Gerardo Sison, Pharm.D., graduated from the University of Florida. He has worked in both community and hospital settings, providing drug information and medication therapy management services. As a medical writer, he hopes to educate and empower patients to better manage their health and navigate their treatment plans.
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Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
Blog articles are not medical advice. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911.
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© 2025 SingleCare Administrators. All rights reserved