What is Gamifant: Uses, Warnings & Interactions

Updated May 14, 2025  •  Published Feb 14, 2024

Gamifant overview

BRAND NAMES:

  • Gamifant

Generic Names:

  • Gamifant

Uses:

  • Treats primary hemophagocytic lymphohistiocytosis.

Therapeutic Classes:

  • Immunological Agent

Forms:

  • Injectable

How it’s taken:

  • By injection

What is Gamifant used for?

What form(s) does Gamifant come in

  • Injectable

What are common Gamifant doses?

  • Vial 10ml of 50mg/10ml

Common Gamifant prescriptions

  • Gamifant
    10ml of 50mg/10ml vial

  • Gamifant
    20ml of 100mg/20ml vial

How to take Gamifant

  • Injection routeYour doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein. The medicine must be given slowly, so the needle will need to stay in place for at least 1 hour.

  • Injection routeA nurse or other health provider will give you this medicine.

  • You may also be given other medicines (including antibiotic, antiviral medicine, steroids) before infusion to prevent serious infections.

What to do if you miss a dose of Gamifant

Gamifant contraindications

  • This medicine is not right for everyone. You should not receive it if you had an allergic reaction to emapalumab-lzsg.

Gamifant warnings

  • Tell your doctor if you are pregnant or breastfeeding, or if you have any type of infection or a weak immune system.

  • This medicine may increase your risk for serious infections and infusion reactions.

  • You will need to have a skin test or blood test for tuberculosis (TB) before you start receiving this medicine. Tell your doctor if you or anyone in your home has ever had a positive TB skin test or has been exposed to TB.

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

Gamifant interactions

  • This medicine may interfere with vaccines. Ask your doctor before you get a flu shot or any other vaccines. You should not receive live or live attenuated vaccines during treatment with this medicine and for at least 4 weeks after the last dose.

Gamifant side effects

Serious Side Effects

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Fever, chills, cough, stuffy or runny nose, sore throat, body aches, painful or difficult urination

  • Skin rash or redness, increased sweating, headache, dizziness, swelling of the face, trouble breathing

Less Serious Side Effects

  • Constipation, diarrhea, stomach pain

  • Irritability

  • Pain, itching, burning, swelling, or a lump under your skin where the needle is placed

  • Vomiting

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