What is Inflectra: Uses, Warnings & Interactions

Updated May 14, 2025  •  Published Jan 25, 2023

Inflectra overview

BRAND NAMES:

  • Inflectra, Renflexis, Remicade

Generic Names:

  • Inflectra

Uses:

  • Treats ankylosing spondylitis, Crohn disease, plaque psoriasis, psoriatic arthritis, rheumatoid arthritis, and ulcerative colitis., Treats rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, Crohn disease, plaque psoriasis, and ulcerative colitis.

Therapeutic Classes:

  • Immunological Agent, Gastrointestinal Agent

Forms:

  • Injectable

How it’s taken:

  • By injection

What is Inflectra used for?

What form(s) does Inflectra come in

  • Injectable

What are common Inflectra doses?

  • Solution Reconstituted 100mg

Common Inflectra prescriptions

  • Inflectra
    100mg solution reconstituted

How to take Inflectra

  • You may also receive other medicines (including allergy medicine, fever medicine, steroids) before starting treatment to help prevent possible unwanted effects during the injection.

  • Injection routeA nurse or other health provider will give you this medicine.

  • This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.

  • Injection routeYour doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein. This medicine must be given slowly, so the needle will have to remain in place for at least 2 hours.

  • Your doctor may also give you other medicines (including allergy medicine, fever medicine, steroid medicine) before or during your infusion.

What to do if you miss a dose of Inflectra

Inflectra contraindications

  • This medicine is not right for everyone. You should not receive it if you had an allergic reaction to infliximab products or murine (mouse) proteins or if you have moderate to severe heart failure.

  • This medicine is not right for everyone. You should not receive it if you had an allergic reaction to infliximab or murine (mouse) proteins or if you have moderate to severe heart failure.

Inflectra warnings

  • This medicine may make you bleed, bruise, or get infections more easily. Take precautions to prevent illness and injury. Wash your hands often.

  • Tell your doctor if you are pregnant or breastfeeding, or if you have liver disease, heart disease, COPD, a bleeding disorder, blood or bone marrow problems, cancer, diabetes, or any type of infection. Tell your doctor if you have a history of seizures, multiple sclerosis, Guillain-Barré syndrome or a similar nervous system disease, or frequent or serious infections (including tuberculosis or hepatitis B).

  • This medicine may cause the following problems:Increased risk for infectionsIncreased risk of certain cancers (including lymphoma, skin cancer, cervical cancer)Liver problemsInfusion reaction (including heart attack, stroke, changes in blood pressure, or heart rhythm problems)Lupus-like syndrome

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

  • You will need to have a skin test for tuberculosis (TB) before you start this medicine. Tell your doctor if you or anyone in your home has ever had a positive TB skin test or been exposed to TB.

  • Unusual bleeding, bruising, tiredness, or weakness

  • Warm, red, swollen, or painful skin, blisters, skin sores

  • This medicine may cause the following problems:Increased risk for infections, which may be life-threateningIncreased risk of certain cancers (including lymphoma, skin cancer, cervical cancer)Liver problemsInfusion reaction (including heart attack, stroke, changes in blood pressure, or heart rhythm problems)

  • You will need to have a skin test for tuberculosis (TB) before you start receiving this medicine. Tell your doctor if you or anyone in your home has ever had a positive TB skin test or been exposed to TB.

  • Tell your doctor if you are pregnant or breastfeeding, or if you have liver disease, heart disease, COPD, a bleeding disorder, blood or bone marrow problems, cancer, diabetes, or any type of infection. Tell your doctor if you have a history of seizures, multiple sclerosis, Guillain-Barré syndrome or a similar nervous system disease, or frequent or serious infections (including tuberculosis or hepatitis B). Tell your doctor if you have recently received or are scheduled to receive a vaccine.

  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.

  • Seizures, numbness, tingling, problems with vision, speech, or walking

Inflectra interactions

  • Some medicines may affect how infliximab-dyyb works. Tell your doctor if you are using any of the following:Abatacept, anakinra, cyclosporine, theophylline, tocilizumabBlood thinner (including warfarin)Medicine that weakens immune system (including ciprofloxacin, methotrexate, metronidazole, aminosalicylate medicine, steroid)

  • Tell your doctor if you have had light treatment for psoriasis.

  • You should not receive a vaccine without your doctor's approval. A live virus vaccine could cause an infection. Children should be current on all vaccines before they start treatment with this medicine. If you received infliximab-dyyb while pregnant, tell the baby's doctor.

  • Some medicines may affect how infliximab works. Tell your doctor if you are using any of the following:Abatacept, anakinra, cyclosporine, etanercept, theophylline, tocilizumabBlood thinner (including warfarin)Medicine that weakens the immune system (including ciprofloxacin, methotrexate, metronidazole, aminosalicylates, steroids)

  • Tell your doctor if you have had light treatment (phototherapy) for psoriasis.

  • This medicine may interfere with vaccines. Ask your doctor before you get a flu shot or any other vaccines.

  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.

Inflectra side effects

Serious Side Effects

  • Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes

  • Joint or muscle pain, swelling, trouble swallowing

  • Unusual bleeding, bruising, tiredness, weakness

  • Headache, lightheadedness, trouble breathing

  • Fever, chills, cough, runny or stuffy nose, sore throat, body aches

  • Seizures, numbness, tingling, problems with vision, speech, or walking

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Warm, red, swollen, or painful skin, blisters, skin sores

  • Change in how much or how often you urinate, pain while urinating

  • Seizures, numbness or tingling of the skin, problems with vision, speech, or walking

  • Unusual bleeding, bruising, tiredness, or weakness

Less Serious Side Effects

  • Diarrhea

  • Redness, pain, or swelling where the needle is placed