What is Methscopolamine Bromide: Uses, Warnings & Interactions

Updated May 14, 2025  •  Published Dec 30, 2020

Methscopolamine Bromide overview

BRAND NAMES:

  • Pamine, Pamine Forte, Pamine Forte

Generic Names:

  • Methscopolamine Bromide

Uses:

  • Treats symptoms of peptic ulcer (wearing away of the lining of the stomach or small intestine).

Therapeutic Classes:

  • Antiemetic, Antivertigo, Gastrointestinal Agent, Urinary Antispasmodic

Forms:

  • Tablet

How it’s taken:

  • By mouth

What is Methscopolamine Bromide used for?

What form(s) does Methscopolamine Bromide come in

  • Tablet

What are common Methscopolamine Bromide doses?

  • Tablet 2.5MG

  • Tablet 5MG

Common Methscopolamine Bromide prescriptions

  • Methscopolamine Bromide
    2.5mg tablet

  • Methscopolamine Bromide
    5mg tablet

How to take Methscopolamine Bromide

  • Your doctor will tell you how much medicine to use. Do not use more than directed.

  • You should take this medicine ½ hour (30 minutes) before your meals and again at bedtime, unless your doctor tells you differently.

  • Your doctor will tell you how much medicine to use. Do not use more than directed.

  • You should take this medicine ½ hour (30 minutes) before your meals and again at bedtime, unless your doctor tells you differently.

What to do if you miss a dose of Methscopolamine Bromide

  • If you miss a dose or forget to take your medicine, call your doctor or pharmacist for instructions.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

  • Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any outdated medicine or medicine no longer needed.

Methscopolamine Bromide contraindications

  • You should not use this medicine if you have had an allergic reaction to methscopolamine (Pamine®), or if you have glaucoma (increased pressure in your eyes). You should not use this medicine if you have intestinal problems (intestinal atony, pyloroduodenal stenosis) or bowel blockage (paralytic ileus), or if you have blockage of your urine flow (obstructive uropathy). You should not use this medicine if you have severe ulcerative colitis or toxic megacolon, or if you have myasthenia gravis.

Methscopolamine Bromide warnings

  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.

  • Avoid spending more time in very hot places. Because this medicine can cause you to sweat less than normal, the heat can make you sick.

  • Make sure your doctor knows if you are pregnant or breast feeding, or if you have liver or kidney problems. Make sure your doctor knows if you have ulcerative colitis, or if you have autonomic neuropathy (damage to the autonomic nerves).

  • This medicine may make you drowsy or dizzy. Avoid driving, using machines, or doing anything else that may be dangerous if you are not alert.

  • Call your doctor if your symptoms do not improve or if they get worse.

  • Make sure your doctor knows if you have hyperthyroidism (overactive thyroid gland), or if you have coronary heart disease. Make sure your doctor knows if you have a very fast heart beat, or if you have high blood pressure. Make sure your doctor knows if you have an enlarged prostate.

  • This medicine can cause diarrhea. Call your doctor if the diarrhea becomes severe, does not stop, or is bloody. Do not take any medicine to stop diarrhea until you have talked to your doctor. Diarrhea can occur 2 months or more after you stop taking this medicine.

  • Make sure your doctor knows if you have ever had problems with or intolerance to anticholinergic medicines. Anticholinergic medicines include antihistamines and tricyclic antidepressants.

Methscopolamine Bromide interactions

  • Make sure your doctor knows if you are also using other medicines with anticholinergic effects. These medicines include tricyclic antidepressants, such as amitriptyline (Elavil®), doxepin (Sinequan®), nortriptyline (Aventyl®, Pamelor®), and antipsychotics, such as chlorpromazine (Thorazine®), clozapine (Clozaril®), or quetiapine (Seroquel®).

  • Make sure your doctor knows if you are also using an antacid medicine, such as aluminum carbonate, magnesium hydroxide, Basalgel®, Gaviscon®, Maalox®, Pepcid®, Pepto-Bismol®, Rolaids®, or Tums®.

  • Make sure your doctor knows if you have ever had problems with or intolerance to anticholinergic medicines. Anticholinergic medicines include antihistamines and tricyclic antidepressants.

  • Avoid spending more time in very hot places. Because this medicine can cause you to sweat less than normal, the heat can make you sick.

  • This medicine may make you drowsy or dizzy. Avoid driving, using machines, or doing anything else that may be dangerous if you are not alert.

  • This medicine can cause diarrhea. Call your doctor if the diarrhea becomes severe, does not stop, or is bloody. Do not take any medicine to stop diarrhea until you have talked to your doctor. Diarrhea can occur 2 months or more after you stop taking this medicine.

  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.

  • Call your doctor if your symptoms do not improve or if they get worse.

Methscopolamine Bromide side effects

Serious Side Effects

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Breast feeding women: Making less milk.

  • Decrease in how much or how often you urinate.

  • Decrease in the amount of sweat.

  • Dry mouth.

  • Fast or uneven heart beat.

  • Feeling unusually nervous, or confused.

  • Headache.

  • Loss of your sense of taste.

  • Men: Problems having or keeping an erection.

  • Nausea, vomiting, constipation, or feeling bloated.

  • Skin rash or redness, or hives.

  • Unable to sleep.

Less Serious Side Effects

  • Decrease in how much or how often you urinate.

  • Unable to sleep.

  • Men: Problems having or keeping an erection.

  • Decrease in the amount of sweat.

  • Feeling unusually nervous, or confused.

  • Blurred vision.

  • Breast feeding women: Making less milk.

  • Headache.

  • Nausea, vomiting, constipation, or feeling bloated.

  • Dry mouth.

  • Loss of your sense of taste.

  • Fast or uneven heart beat.

  • Skin rash or redness, or hives.

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