Metolazone is an FDA-approved, oral, prescription drug that reduces water in the body in patients who have edema (fluid retention) due to heart failure or kidney disease. Metolazone is also used to treat high blood pressure. Metolazone is a diuretic (water pill) that flushes the body of water and salt. The retail price for Metolazone is $83.36, but the price with a SingleCare Metolazone coupon is $13.68.
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SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.
Prices updated: 12/06/2025
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Metolazone is an FDA-approved, oral, prescription drug that reduces water in the body in patients who have edema (fluid retention) due to heart failure or kidney disease. Metolazone is also used to treat high blood pressure. Metolazone is a diuretic (water pill) that flushes the body of water and salt. The retail price for Metolazone is $83.36, but the price with a SingleCare Metolazone coupon is $13.68.
Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.
| Pharmacy | Metolazone Retail Price | Metolazone SingleCare Price |
|---|---|---|
| CVS Pharmacy | $84.00 | $16.80 |
| Walmart | $65.52 | $39.24 |
| Walgreens | $87.90 | $35.50 |
| Kroger Pharmacy | $70.50 | $42.30 |
These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.
Metolazone is an FDA-approved, oral, prescription drug that reduces water in the body in patients who have edema (fluid retention) due to heart failure or kidney disease. Metolazone is also used to treat high blood pressure. Metolazone is a diuretic (water pill) that flushes the body of water and salt. The retail price for Metolazone is $83.36, but the price with a SingleCare Metolazone coupon is $13.68.
Without insurance, customers can expect to pay a cash price of $83.36 for Metolazone, but this price may vary. With a SingleCare prescription savings card, the cost of Metolazone drops to $13.68.
Your copay for Metolazone with insurance will vary depending on your insurance plan. Ask your pharmacist to compare your insurance copay to your cost with a SingleCare Metolazone coupon. You may find your SingleCare prescription discount card saves you money – with SingleCare, Metolazone costs $13.68 per 30, 5mg tablets.
As a widely-available generic medication, Metolazone is covered for Medicare-eligible patients under Medicare Part D and Medicare Advantage. Patients without Medicare prescription drug coverage can save money with a free coupon for Metolazone from SingleCare– the discount price of Metolazone with a SingleCare savings card is $13.68.
Metolazone is a generic prescription drug and the active ingredient in the brand-name drug, Zaroxolyn. Zaroxolyn is no longer available in the brand-name form—only generic Metolazone is available. At the present time, several pharmaceutical companies manufacture generic Metolazone, including Aphena, Mylan, and Sandoz, among others. Before you pay for your Metolazone prescription, find free coupons for the generic or brand-name Metolazone on our website or app.
Metolazone is an oral prescription drug that reduces water in the body in patients who have edema (fluid retention) due to heart failure or kidney disease. Metolazone is also used to treat high blood pressure.
Metolazone is a diuretic (“water pill”) that flushes the body of water and salt. Metolazone works by reducing the kidney's ability to reabsorb water or salt from the urine. This will reduce swelling due to heart failure or kidney disease. Before you take Metolazone, review your medical conditions and medical history with your doctor. Also tell your doctor about all of the medications you take, including prescription and OTC drugs, vitamins, and supplements.
The most common side effects of Metolazone are electrolyte imbalances, such as low potassium, sodium, magnesium, and chloride, and high levels of calcium. A common side effect is feeling dizzy when going from a sitting or lying down position to standing up—this is called orthostatic hypotension. Other common side effects include headache, tiredness, weakness, diarrhea, muscle pain, and itching.
Allergic reactions to Metolazone are rare. If you have symptoms of an allergic reaction such as hives, trouble breathing, or swelling around the face, lips, tongue, or throat, get emergency medical attention. If you have symptoms of a severe skin reaction, such as red or purple rash, fever, or blistering or peeling skin, get emergency medical help.
This is not a complete list of side effects. Consult your doctor or healthcare professional for additional information and medical advice regarding other possible side effects or drug interactions.
After receiving her doctorate from the University of Pittsburgh School of Pharmacy, Karen Berger, Pharm.D., has worked in both chain and independent community pharmacies. She currently works at an independent pharmacy in New Jersey. Dr. Berger enjoys helping patients understand medical conditions and medications—both in person as a pharmacist, and online as a medical writer and reviewer.
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Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
Blog articles are not medical advice. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911.
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© 2025 SingleCare Administrators. All rights reserved