What is Percogesic: Uses, Warnings & Interactions

Updated May 14, 2025  •  Published Dec 30, 2020

Percogesic overview

BRAND NAMES:

  • Dolorex, Percogesic, Rhinoflex-650, Novagesic, Percogesic, Rhinoflex-650, Keygesic-10, Percogesic, Percogesic, Doan's Regular, DeWitt's Pain Reliever, Dolorex, Percogesic, Relagesic, Rhinoflex-650, Relagesic, Rhinoflex-650

Generic Names:

  • Percogesic

Uses:

  • Treats minor pain, reduces fever, and relieves cold and flu symptoms., Treats pain, decreases fever, and helps decrease certain allergy and hay fever symptoms., Relieves pain and swelling in rheumatoid arthritis and osteoarthritis.

Therapeutic Classes:

  • Acetaminophen/Salicylate, Non-Aspirin Combination, Acetaminophen Combination, Analgesic, Skeletal Muscle Relaxant, Centrally Acting/Acetaminophen Combination, Analgesic, Antipyretic, Antirheumatic, Acetaminophen Combination, Analgesic, Antihistamine, Ethanolamine/Acetaminophen Combination, Skeletal Muscle Relaxant, Centrally Acting/Acetaminophen Combination

Forms:

  • Tablet, Tablet, Capsule, Liquid Filled Capsule, Liquid, Tablet

How it’s taken:

  • By mouth, By mouth, By mouth

What is Percogesic used for?

What form(s) does Percogesic come in

  • Tablet

  • Tablet

  • Capsule

  • Liquid Filled Capsule

  • Liquid

  • Tablet

What are common Percogesic doses?

  • Bottle 24 Tablets

  • Bottle 50 Tablets

  • Bottle 90 Tablets

How to take Percogesic

  • Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.

  • Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.

  • Your doctor will tell you how much medicine to use. Do not use more than directed.

  • This medicine contains acetaminophen. Read the labels of all other medicines you are using to see if they also contain acetaminophen, or ask your doctor or pharmacist. Do not use more than 4 grams (4,000 milligrams) total of acetaminophen in one day.

  • Do not use this medicine for pain for more than 10 days in an adult, or for more than 5 days in a child. Do not take it for fever for more than 3 days, unless your doctor tells you to.

  • Liquid: Measure the oral liquid medicine with a marked measuring spoon, oral syringe, or medicine cup.

  • Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

  • Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

  • This medicine contains acetaminophen. Read the labels of all other medicines you are using to see if they also contain acetaminophen, or ask your doctor or pharmacist. Do not use more than 4 grams (4,000 milligrams) total of acetaminophen in one day.

  • Do not use this medicine for pain for more than 10 days in an adult, or for more than 5 days in a child. Do not take it for fever for more than 3 days, unless your doctor tells you to.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

  • Your doctor will tell you how much medicine to use. Do not use more than directed.

  • Liquid: Measure the oral liquid medicine with a marked measuring spoon, oral syringe, or medicine cup.

  • Your doctor will tell you how much medicine to use. Do not use more than directed.

  • Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

  • Your doctor will tell you how much medicine to use. Do not use more than directed.

  • Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

What to do if you miss a dose of Percogesic

  • Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

  • Oral routeAsk your pharmacist, doctor, or health caregiver about the best way to dispose of any outdated medicine or medicine no longer needed.

Percogesic contraindications

  • You should not use this medicine if you have had an allergic reaction to magnesium salicylate or aspirin. Do not use this medicine if you have kidney disease, liver disease, or a heart disease called carditis, or if you have taken salicylates (such as aspirin) over a long period of time.

  • This medicine is not right for everyone. Do not use it if you had an allergic reaction to acetaminophen or to phenyltoloxamine. Do not give this medicine to children younger than 6 years, unless a doctor tells you to. Do not give this medicine to treat arthritis pain in children younger than 12 years unless a doctor tells you to.

  • This medicine is not right for everyone. Do not use it if you had an allergic reaction to acetaminophen or phenyltoloxamine.

Percogesic warnings

  • Make sure your doctor knows if you are pregnant or breastfeeding.

  • This medicine may cause unusual bleeding in certain people. Make sure your doctor knows if you have bleeding problems, a vitamin K deficiency, stomach ulcers, or gastritis. Tell your doctor if you have unusual bleeding, such as nosebleeds, bleeding gums, dark urine, or blood in your stool.

  • Deep or fast breathing with dizziness, numbness of feet, hands and around the mouth.

  • Tell any doctor or dentist who treats you that you are using this medicine. You may need to stop using this medicine several days before you have surgery or medical tests.

  • Continuous ringing or buzzing noise in ears.

  • Dimness of vision.

  • Restlessness, tremors, or convulsions.

  • Unusual bleeding, bruising or weakness.

  • Vomiting of blood or material that looks like coffee grounds.

  • Tell your doctor if you are pregnant or breastfeeding.

  • Tell your doctor if you have glaucoma, kidney or liver problems, breathing problems such as asthma or COPD (emphysema or chronic bronchitis), or trouble urinating due to an enlarged prostate gland. Tell your doctor if you drink alcohol on a regular basis.

  • This medicine may make you drowsy. Do not drive or use machines if you are not alert.

  • Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

  • Call your doctor if your symptoms do not improve or if they get worse.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

  • This medicine contains acetaminophen. Read the labels of all other medicines you are using to see if they also contain acetaminophen, or ask your doctor or pharmacist. Do not use more than 4 grams (4,000 milligrams) total of acetaminophen in one day.

  • Tell your doctor if you are pregnant or breastfeeding, or if you have liver or kidney disease.

  • This medicine may make you dizzy or drowsy. Do not drive or use machines if you are not alert.

Percogesic interactions

  • Some medicines and foods can affect how this medicine works. Tell your doctor if you are taking any of the following: A blood thinner, such as warfarinMedicine that contains acetaminophenMedicine that makes you sleepy, such as allergy medicine or narcotic pain medicine

  • Do not drink alcohol while you are using this medicine. Acetaminophen can damage your liver, and alcohol can increase this risk. If you regularly drink 3 or more alcoholic drinks every day, do not take any medicines that contain acetaminophen without asking your doctor. A drink of alcohol is 12 ounces of beer, 4 ounces of wine, or 1 ounce of liquor.

  • This medicine contains acetaminophen. Read the labels of all other medicines you are using to see if they also contain acetaminophen, or ask your doctor or pharmacist. Do not use more than 4 grams (4,000 milligrams) total of acetaminophen in one day.

  • Call your doctor if your symptoms do not improve or if they get worse.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

  • Some medicines and foods can affect how this medicine works. Tell your doctor if you are taking any medicine that contains acetaminophen.

  • Do not drink alcohol while you are using this medicine. Acetaminophen can damage your liver, and alcohol can increase this risk. If you regularly drink 3 or more alcoholic drinks every day, do not take any medicines that contain acetaminophen without asking your doctor. A drink of alcohol is 12 ounces of beer, 4 ounces of wine, or 1 ounce of liquor.

  • Tell your doctor if you use anything else that makes you sleepy. Some examples are allergy medicine, narcotic pain medicine, and alcohol.

  • Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

  • You should not take this medicine with a blood thinner such as warfarin (Coumadin®), probenecid (Probalan®), or methotrexate (Trexall®). Make sure your doctor knows if you are using medicines to treat seizures (such as phenobarbital, phenytoin, or Dilantin®) or a diuretic ("water pill") called spironolactone (Aldactazide®, Aldactone®).

  • Your doctor will need to know if you are using a diabetes medicine that you take by mouth, such as chlorpropamide, glimepiride, glipizide, glyburide, tolbutamide, Amaryl®, Diabeta®, Glucotrol®, or Micronase®. You should not take medicines that contain magnesium, such as antacids (Gaviscon®, Maalox®, Mylanta®) or nutritional supplements, without asking your doctor.

  • Tell any doctor or dentist who treats you that you are using this medicine. You may need to stop using this medicine several days before you have surgery or medical tests.

Percogesic side effects

Serious Side Effects

  • Unusual bleeding, bruising, or weakness

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Skin rash, redness, or swelling

  • Unusual bleeding, bruising, or weakness

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Fever that continues for longer than 3 days after you started taking this medicine

  • Pain that continues for longer than 10 days after you started taking this medicine

  • Continuous ringing or buzzing noise in ears.

  • Confusion, lightheadedness, shaking, or hunger.

  • Black, tarry stools.

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Restlessness, tremors, or convulsions.

  • Dimness of vision.

  • Vomiting of blood or material that looks like coffee grounds.

  • Unusual bleeding, bruising or weakness.

  • Deep or fast breathing with dizziness, numbness of feet, hands and around the mouth.

Less Serious Side Effects

  • Headache.

  • Difficulty in hearing.

  • Nausea, vomiting, or diarrhea.

  • Increased thirst or sweating.

  • Nausea or vomiting

  • New or worsening symptoms

  • Excitability or other mood or behavior changes, especially in children

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