Key takeaways
Qsymia is a prescription appetite suppressant for weight loss.
The average monthly cost of Qsymia is $282 for 30, 7.5 mg/46 mg capsules.
Savings options include switching to generic Qsymia, using a SingleCare discount card, comparing pharmacy prices, or considering alternative treatments.
Qsymia is a brand-name prescription drug used along with a reduced-calorie diet and increased physical activity for chronic weight management. Each Qsymia capsule contains two appetite suppressants: phentermine and topiramate. The average Qsymia price is $282 for 30, 7.5 mg/46 mg capsules. Most insurance companies cover Qsymia or its generic version, but people without insurance can save money by using SingleCare discounts, comparing prices, or switching to generic phentermine.
Related: What is Qsymia?
How much does brand-name Qsymia cost?
The cost of Qsymia therapy is around $282 for 30, 7.5 mg/46 mg capsules without health insurance coverage. The actual cost will depend on the individual pharmacy.
The active ingredients in Qsymia are low-dose phentermine combined with topiramate. It is also available as a lower-cost generic, phentermine and topiramate extended release.
The generic version of phentermine alone is not an equivalent substitute because of the higher risk of adverse effects. The dosage strength of generic phentermine (37.5 mg) is much higher than the amount of phentermine in the recommended dosage of Qsymia (7.5 mg). Phentermine is a potentially hazardous drug that can cause serious side effects, including medication tolerance and drug abuse. Qsymia capsules contain a low dose of phentermine. The topiramate compensates for the reduced phentermine dose. A medical provider should only prescribe generic phentermine for a few weeks because of potential adverse events and drug interactions. On the other hand, the Food and Drug Administration (FDA) has approved Qsymia treatment for long-term weight management.
RELATED: Qsymia vs. phentermine: differences, similarities, & side effects
Compare Qsymia prices to related drugs |
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|---|---|---|---|
| Drug name | Price without insurance of brand-name drug | SingleCare price | Savings options |
| Qsymia
(phentermine-topiramate) |
$282 for 30, 7.5 mg/46 mg capsules | $67 for 30, 7.5 mg/46 mg capsules of generic Qsymia at Costco | See latest prices |
| Phentermine | $53 for 30, 37.5 mg tablets | $10 for 30, 37.5 mg tablets of generic phentermine at Kroger | See latest prices |
| Lomaira
(phentermine) |
$40 for 30, 8 mg tablets | $26 for 30, 8 mg tablets of brand-name Lomaira at CVS | See latest prices |
| Contrave
(bupropion-naltrexone) |
$837 for 120, 8 mg/90 mg tablets | $613 for 120, 8 mg/90 mg tablets of brand-name Contrave at Kroger | See latest prices |
| Wegovy (semaglutide) | $1,917 for 30, 1.5 mg tablets | $1,011 for 30, 1.5 mg tablets of brand-name Wegovy at Kroger | See latest prices |
| Zepbound (tirzepatide) | $659 for 1, 2.5 mg/0.6 mL 2.4 mL Kwikpen (a four-week supply) | $409 for 1, 2.5 mg/0.6 mL 2.4 mL brand-name Zepbound Kwikpen (a four-week supply) at Kroger | See latest prices |
Qsymia costs by dose
The retail price of Qsymia for self-paying customers may vary by dosage strength. In addition, the doctor may prescribe a six-week “New Patient Pack” at the start of therapy. It may be priced differently from later 30-day prescriptions. There’s also a titration pack containing different dosage strengths, which may not match the price of a month’s supply of Qsymia.
Compare Qsymia prices by strength |
||
|---|---|---|
| Strength | SingleCare price of brand-name Qsymia | SingleCare price of generic phentermine-topiramate |
| 3.75 mg/23 mg | $211 for 30 extended-release capsules at Walgreens | $90 for 30 extended-release capsules at CVS Pharmacy |
| 7.5 mg/46 mg | $218 for 30 extended-release capsules at Walgreens | $67 for 30 extended-release capsules at Costco |
| 11.25 mg/69 mg | $234 for 30 extended-release capsules at Walgreens | $129 for 30 extended-release capsules at Walgreens |
| 15 mg/92 mg | $234 for 30 extended-release capsules at Walgreens | $125 for 30 extended-release capsules at CVS Pharmacy |
| See our lowest price for Qsymia without insurance | ||
Is Qsymia covered by insurance?
A majority of health insurance plans cover Qsymia, but not all. Medicare plans do not cover weight loss drugs such as Qsymia. Medicaid coverage varies by state. Qsymia is generally placed in the middle copay tiers for people with health insurance, so you can check with your insurance company to find out your out-of-pocket cost.
RELATED: What obesity treatments does insurance cover?
How to get Qsymia covered by insurance
Although Qsymia is covered by many insurance plans, approval may require prior authorization. The prescriber will need to submit paperwork to the health insurance company explaining why a Qsymia prescription is necessary. Less commonly, the health plan may require step therapy, which involves using other drugs first to see if they work. If the insurance plan does not cover Qsymia, patients can contact the insurance provider and ask about a formulary exception. The paperwork is very similar to a prior authorization.
How to get Qsymia without insurance
There are ways to save on weight loss medications like Qsymia if you don’t have insurance or if your insurance doesn’t cover Qsymia.
1. Use a SingleCare savings card
The lowest SingleCare discounted price for generic Qsymia is only $67 for 30, 7.5 mg/46 mg capsules. This represents a savings of about $215 off the average monthly price of brand-name Qsymia. Discount prices will vary at participating pharmacies, so browse available savings on SingleCare’s Qsymia coupons page. SingleCare is free to use and available to everyone. Registered members can save even more, and it’s fast and free to join.
2. Shop for the lowest price
Drug prices vary by pharmacy, sometimes by a lot. By using SingleCare to compare prices at pharmacies near you, you can choose the pharmacy with the lowest-priced coupon and transfer your prescription if need be.
RELATED: How do I use the SingleCare app?
3. Ask your healthcare provider about alternatives
The Qsymia generic cost without insurance is $226 for 30, 7.5 mg/46 mg capsules, a savings of $50 off the brand-name version. The weight loss drug in Qsymia is phentermine, a short-term obesity medication. The average cost of generic phentermine is low. A 30-day supply of generic phentermine costs about $53 for 30, 37.5 mg tablets. A 30-day supply of Lomaira, a low-dose phentermine generic, costs even less.
One lower-cost alternative for weight management is Plenity. It’s not a drug, though it’s taken before each meal as a capsule. It’s an FDA-cleared medical device filled with a gel that expands in the stomach and makes people feel full so that they will eat less. It costs $131 for a three-month supply, but you could pay $98 with a SingleCare discount, depending on your choice of pharmacy. Ask a healthcare provider for medical advice before trying this treatment.
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The SingleCare prices in this article are the most accurate at the time of publishing in ZIP code 23666 as of Jul. 14, 2026. Prices vary by pharmacy. Visit our coupon page for updated drug prices at pharmacies near you.
- Phentermine hydrochloride tablet prescribing information, DailyMed (NIH National Library of Medicine) (2024)
- Qsymia phentermine and topiramate capsule extended release prescribing information, DailyMed (NIH National Library of Medicine) (2026)
- Qsymia HCP, Vivus LLC (2026)
- Plenity (oral superabsorbent hydrogel), Clinical Diabetes (2020)
- Medically accurate: SingleCare’s Medical Review Board analyzes all of our content to confirm it’s in line with current medical advice.
- Evidence-based: Our content is sourced from reputable U.S.-based healthcare professionals and peer-reviewed research.
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