Key takeaways
The average retail price of Synjardy is around $852 for 60, 12.5–1,000 mg tablets, and $857 for Synjardy XR (extended-release) without insurance.
In most cases, insurance plans will cover Synjardy, as long as it’s prescribed for someone with Type 2 diabetes and not for an off-label purpose.
There are ways to save money on Synjardy if you don’t have insurance, and SingleCare coupons can help you save over $600 per month.
Synjardy contains two medications, metformin and empagliflozin, to control blood sugar levels in people with Type 2 diabetes. Because it contains empagliflozin, it may also be used in people with Type 2 diabetes to reduce the risk of cardiovascular (CV) death and hospitalization in adults with CV disease or heart failure, and to reduce the risk of kidney disease progression. Synjardy is convenient because it combines two medications in one pill, but it can also be expensive without insurance or a prescription discount card. Thankfully, there are ways to save, including your SingleCare prescription discount card or the Synjardy savings card, if you qualify.
How much does Synjardy cost?
For people paying completely out of pocket with no insurance coverage or other savings methods, Synjardy’s average retail price is $852 for 60, 12.5–1,000mg tablets. At that price, it could end up costing more than $10,000 per year. Fortunately, there are several reliable ways to reduce that price.
Synjardy also has an extended-release formulation called Synjardy XR, but it’s typically around the same price as the standard version. The average retail price is $846 for a supply of 60, 12.5–1,000 mg tablets.
Does insurance cover Synjardy?
In many cases, yes, insurance is likely to cover Synjardy. According to Synjardy’s manufacturer, Boehringer Ingelheim, over 90% of people who have commercial insurance or Medicare Part D have access to Synjardy or Synjardy XR. On some drug formularies, it’s even available at the lowest branded copay. However, the amount and type of coverage depend on the specific plan.
Most of the time, insurance plans will only provide coverage when Synjardy is prescribed for an FDA-approved purpose. For example, some healthcare providers may prescribe it for weight loss, but that’s an off-label use, so it might not be covered. It’s only indicated to control blood sugar, lower the risk of cardiovascular death, and lower the risk of kidney decline in people with Type 2 diabetes. It is typically not a first-line medication for diabetes, cardiovascular disease, or weight loss.
On top of that, some plans may require prior authorization before they will issue coverage for Synjardy. Per Elizabeth Rubin, MD, clinical adviser at Embers Recovery, these requirements often involve a documented contraindication to generic metformin, while some plans might require patients to try and fail metformin or another SGLT2 inhibitor first. Many common commercial insurance plans categorize it as a Tier 2 or Tier 3 medication, which means it requires prior authorization, higher copays, or cost-sharing. “My advice to patients is to communicate promptly with office staff about any prior authorization denials,” she says. “They are best equipped to handle the administrative appeals process and provide the necessary clinical documentation to the insurance company.”
How to save money on Synjardy
Health insurance is a common and effective way to save money on Synjardy, but insurance isn’t an option for everyone. Fortunately, there are a few other ways to save on Synjardy without insurance.
1. Free Synjardy coupons
SingleCare has coupons that can drop the prices on thousands of medications, including Synjardy. With a Synjardy coupon from SingleCare, you could pay $244 instead of $852 for 60, 12.5–1,000 mg tablets.
The cost of Synjardy XR without insurance is similar. With a Synjardy XR coupon from SingleCare, you could pay $244 instead of $846 for 60, 12.5–1,000 mg tablets.
All you have to do is search the SingleCare website or app for Synjardy and type in your ZIP code to see a list of pharmacies near you, along with how much you can save with your SingleCare prescription discount card. Prices vary by pharmacy, so choose the coupon for the pharmacy you want your healthcare provider to send your prescription to and then click on the “Get free coupon” link. You can save it to your phone, print it, or text it to yourself and show it to the pharmacy staff at checkout to be charged the SingleCare price. You don’t have to sign up or register to use SingleCare Synjardy coupons, but members save even more, and it’s completely free to sign up.
2. Medicare or Medicaid savings
Whether you have insurance coverage for Synjardy or not, you might be eligible for Medicaid benefits. To qualify, you’ll need to meet certain income requirements, although these vary by state. Each state’s Medicaid program has its own formulary with approved medications, meaning that it may or may not be on your state’s formulary.
Medicare also has assistance for people who may need help paying their medical expenses. People who have Medicare Part D can apply for the Extra Help program, a low-income federal subsidy that helps cover premiums, deductibles, coinsurance, and other costs.
For individualized, plan-specific copay information, reach out to your insurance company.
3. Synjardy savings card
Synjardy’s manufacturer offers a discount card, which can help eligible patients get the drug for as low as $10 per prescription. However, not everyone is eligible. To qualify, you must:
- Be at least 18 years old
- Be a resident of the U.S. or Puerto Rico
- Have commercial insurance that covers Synjardy, but not the full cost
- Not be enrolled in any government-funded assistance plans, including Medicare, Medicaid, TRICARE, or VA benefits.
Additionally, there’s a $7,000 limit on annual savings, so it might not last for the full year if your out-of-pocket costs are particularly high. In that case, or for people without commercial insurance, SingleCare prices might end up being lower in the long run. It all depends on your specific insurance plan. You can’t use insurance and SingleCare in the same transaction, but SingleCare coupons for Synjardy can help you save when the Synjardy savings card can’t.
4. Synjardy patient assistance program
Aside from the Synjardy discount program, Boehringer Ingelheim also has a broader patient assistance program, which provides free prescription drugs to applicants who meet the eligibility requirements. For Synjardy, qualifying applicants must be a resident of the U.S. or a U.S. territory, be uninsured or have Medicare Part D, and have a household income of 250% or less of the federal poverty level.
5. 90-day prescriptions
Some healthcare providers might be open to writing 90-day prescriptions instead of 30-day prescriptions. According to a study from the Medicare & Medicaid Research Review, 90-day prescriptions can lead to savings for some patients.
“Many pharmacy benefit managers offer a lower copay for a 90-day supply than for three separate 30-day fills,” Dr. Rubin says. “Additionally, longer supply intervals significantly improve patient adherence by reducing the frequency of pharmacy visits and the risk of running out of medication, which ultimately leads to better health outcomes and fewer complications.”
6. Comparing prices
Every pharmacy is different, and its prescription medication prices can fluctuate based on several factors, including its location. So a local pharmacy might have a higher or lower price than a different one across town. SingleCare makes it easy to compare prices near you, whether at SingleCare.com or on the SingleCare app.
Diabetes Coupons & Discount Diabetic Supplies
Is there a cheaper alternative to Synjardy?
Unfortunately, there’s no generic version of Synjardy, but there are Synjardy alternatives that might be less expensive based on your insurance plan and location. For example, metformin is one of Synjardy’s active ingredients, and it costs less than $10 with a SingleCare coupon. The other active ingredient, empagliflozin, is only sold under the brand name Jardiance, and it’s usually around the same price as Synjardy.
Other combination diabetes medications that may be more affordable than Synjardy include Trijardy XR (empagliflozin/linagliptin/metformin ER) and Janumet (sitagliptin/metformin). GLP-1 drugs like Ozempic (semaglutide), Mounjaro (tirzepatide), and Rybelsus (semaglutide) are also options, although they are typically more expensive than Synjardy.
The best Synjardy alternative for you depends on your individual health needs. “If the SGLT2 benefit is key, such as for patients with established cardiovascular disease, heart failure, or chronic kidney disease, I would favor a single-agent SGLT2 inhibitor like Jardiance (empagliflozin) or Farxiga (dapagliflozin) combined with generic metformin,” Dr. Rubin says. “If cost is the primary barrier, I often recommend maximizing the dose of low-cost generic metformin and adding a sulfonylurea like glimepiride or glipizide, while closely monitoring for hypoglycemia.”
Regardless, an alternative to Synjardy is only viable if a healthcare professional thinks it’s a good fit for you. If you need help paying for your Synjardy prescription and you’re considering alternatives, consult your healthcare provider. They can provide personalized recommendations and potentially prescribe a different medication if they think one will be more effective.
The SingleCare prices in this article are the most accurate at the time of publishing in ZIP code 23666 as of Jan. 16, 2026. Prices vary by pharmacy. Visit our Synjardy coupon page for updated Synjardy prices near you.
- Savings & Support, Boehringer Ingelheim
- Synjardy label, DailyMed (2025)
- Help with drug costs, Centers for Medicare & Medicaid Services
- Medication days’ supply, adherence, wastage, and cost among chronic patients in Medicaid, Medicare & Medicaid Research Review (2012)