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Dulera vs Advair: Main Differences and Similarities

Dulera and Advair are two inhaled prescription medications that can help treat asthma. Both medications contain the same types of ingredients: an inhaled corticosteroid (ICS) and a long-acting beta agonist (LABA). They are used for long-term maintenance treatment to prevent symptoms such as shortness of breath, coughing, and wheezing.

Dulera

Dulera is the brand name for the combination of mometasone (ICS) and formoterol (LABA). It is approved to treat asthma in those aged 12 years and older.

Dulera is supplied as a 100 mcg/5 mcg or 200 mcg/5 mcg inhalation aerosol. Although it depends on your doctor’s instruction, the usual dose is 2 inhalations twice daily.

Advair

Advair is the brand name for the combination of fluticasone (ICS) and salmeterol (LABA). It is approved to treat asthma in those aged 4 years and older. Advair can also help treat COPD.

Advair HFA is available as a 45/21 mcg, 115/21 mcg, and 230/21 mcg aerosol inhaler. There is also an Advair Diskus that contains a powdered form of drug. Advair is usually taken twice daily.

Note: Advair HFA is recommended only for asthma while Advair Diskus can be used for either asthma or COPD.

Dulera vs Advair Side by Side Comparison

Dulera and Advair are similar inhaled medications. While they both can treat asthma, they have some differences. These drugs are compared in the table below.

Dulera Advair
Prescribed For
  • Asthma
  • Asthma
  • Chronic Obstructive Pulmonary Disease (COPD)
Drug Classification
  • Long-acting beta-agonist (LABA)/inhaled corticosteroid (ICS)
  • Long-acting beta-agonist (LABA)/inhaled corticosteroid (ICS)
Manufacturer
Common Side Effects
  • Headache
  • Upper respiratory infection
  • Nasopharyngitis
  • Oral candidiasis
  • Sinusitis
  • Headache
  • Upper respiratory tract infection
  • Pharyngitis
  • Oral candidiasis
  • Pneumonia
  • Bronchitis
  • Nausea
  • Vomiting
  • Sore throat
  • Dizziness
  • Trouble speaking
  • Musculoskeletal pain
Is there a generic?
  • No generic available
  • No generic available
Is it covered by insurance?
  • Varies according to your provider
  • Varies according to your provider
Dosage Forms
  • Inhalation aerosol
  • Inhalation aerosol
  • Inhalation powder
Average Cash Price
  • $380 for 13, 13gm of 200-5mcg inhalation canisters
  • $498.27 per 1 inhaler (230mcg-21mcg)
SingleCare Discount Price
Drug Interactions
  • CYP3A4 inhibitors (ketoconazole, clarithromycin, HIV protease inhibitors, etc.)
  • MAO inhibitors (isocarboxazid, selegiline, etc.)
  • Tricyclic antidepressants (nortriptyline, desipramine, etc.)
  • Beta-blockers (metoprolol, carvedilol, etc.)
  • Diuretics (hydrochlorothiazide, furosemide, etc.)
  • CYP3A4 inhibitors (ketoconazole, clarithromycin, HIV protease inhibitors, etc.)
  • MAO inhibitors (isocarboxazid, selegiline, etc.)
  • Tricyclic antidepressants (nortriptyline, desipramine, etc.)
  • Beta-blockers (metoprolol, carvedilol, etc.)
  • Diuretics (hydrochlorothiazide, furosemide, etc.)
Can I use while planning pregnancy, pregnant, or breastfeeding?
  • Dulera is in Pregnancy Category C. Consult a physician regarding taking Dulera while pregnant or breastfeeding.
  • Advair is in Pregnancy Category C. Consult a physician regarding taking Advair while pregnant or breastfeeding.

Summary

Dulera and Advair are potential options if you suffer from asthma. Both medications can be used for long-term treatment to prevent respiratory symptoms. While both drugs can help treat asthma, Advair can also be used to treat COPD.

Dulera is only approved for those aged 12 years and older while Advair is approved for those aged 4 years and older. Dulera is available as an inhaler that can be used twice daily. Advair is available as both an inhaler and a powdered diskus.

Both medications have similar side effects and drug interactions. For example, they can both increase the risk of respiratory infections. Because both medications contain an inhaled steroid, they should be rinsed out of the mouth after use to prevent oral candidiasis, a mild fungus.

Discuss these medications with a doctor to determine the best treatment option for you. Both medications are equally effective in treating asthma. Therefore, their use should be individualized on what works for your asthma.