Dupixent copay card & savings guide

In this article:

• How much does Dupixent cost?
• Why is Dupixent so expensive?
• Dupixent copay card details
• Can you get Dupixent for free?
• Other ways to save money on Dupixent
• Is there a cheaper alternative to Dupixent?

In this article

• How much does Dupixent cost?
• Why is Dupixent so expensive?
• Dupixent copay card details
• Can you get Dupixent for free?
• Other ways to save money on Dupixent
• Is there a cheaper alternative to Dupixent?

Dupixent (dupilumab) is an injectable monoclonal antibody that treats several different inflammatory conditions, including moderate-to-severe atopic dermatitis and other less common autoimmune conditions. It’s also used as an add-on treatment for moderate-to-severe asthma and COPD. If your healthcare provider prescribes Dupixent, you may be worried about how to afford it. Dupixent is a brand-name drug that requires specialty handling. There is no lower-priced generic alternative, but there are ways to get affordable or even free Dupixent. 

How much does Dupixent cost?

The list price of Dupixent is $4,193 for two 2-milliliter (mL) syringes, according to Dupixent’s manufacturer, Sanofi and Regeneron Pharmaceuticals, Inc. However, the list price isn’t the price most people pay. The actual cost you pay can vary greatly, as it depends on several different factors, including:

• The dosing schedule (every two weeks or every week)
• Whether you have prescription drug insurance
• The diagnosis code your provider uses when prescribing dupixent
• The type of insurance you have
• Whether your insurance company considers the medication to be preferred or nonpreferred
• Whether you’ve met your deductible
• The pharmacy you choose

Why is Dupixent so expensive?

Drug manufacturers often spend years researching and developing a medication. They can place any price they choose on a medication. Specialty drugs are typically high-cost prescription medications used to treat chronic, complex conditions such as rheumatoid arthritis, cancer, or multiple sclerosis. You will likely get Dupixent from a specialty pharmacy. Your healthcare provider will guide you through the process.

“It’s very effective for patients whose eczema isn’t well-controlled with topical treatments,” says Richard Linsky, MD, clinical assistant professor of emergency medicine at NYU Langone.

Insurance coverage for Dupixent

Medicare, Medicaid, and other types of insurance may cover Dupixent, but it depends on the plan. According to the manufacturer, 99% of commercially insured patients are covered for Dupixent. However, insurance companies typically place restrictions on coverage of expensive medications, such as prior authorization. In those cases, the prescriber will need to submit additional documentation and possibly a letter of medical necessity proving that other medications have been tried but haven’t worked. Each insurance plan can require different documentation and may cover the medication for different diagnosis codes. 

The Dupixent website has a cost and coverage tool that can help you check your insurance coverage, but calling your insurance company and speaking to a representative may provide a more accurate idea of what you can expect to pay and which diagnosis codes may help the insurance approve coverage for Dupixent. 

If your insurance company refuses to cover Dupixent, there are ways to lower the cost and make it more affordable. 

Dupixent copay card details

With the Dupixent MyWay copay card, eligible patients with commercial health insurance could pay a $0 copay per fill of Dupixent, but there’s a maximum savings of $13,000 per patient per calendar year. If you’re eligible, you can enroll online or phone the manufacturer.

Eligible patients must have commercial insurance, including marketplace exchange plans, federal employee plans, or state employee plans. Check the manufacturer’s website for more eligibility requirements.

Can you get Dupixent for free?

You can get Dupixent for free if you qualify for the Dupixent Patient Assistance Program. The program is available to all patients with or without insurance, but they must first enroll in the manufacturer’s Dupixent support program, Dupixent MyWay. To enroll in Dupixent MyWay, your healthcare provider will need to complete and sign the enrollment form. Once enrolled, you can call a Dupixent MyWay case manager to explore your savings options. 

The program typically has a cut-off of 300% of the federal poverty level, but decisions are made on a case-by-case basis. Although only adults are covered, it’s understood that minors are under the care of a parent, so the parent will qualify for patient assistance for their minor child.

Other ways to save money on Dupixent

Besides the Dupixent MyWay copay card and Patient Assistance Program, it’s possible to save on Dupixent with SingleCare coupons and extra government assistance.

SingleCare coupons

Dupixent is a limited availability drug, but if it is in stock at your local pharmacy, you may be able to save with a SingleCare coupon. Check our Dupixent coupon page when it’s time to fill your prescription to see whether it’s available at a pharmacy near you and, if so, how much you can save with your free SingleCare card. SingleCare helps patients save a significant amount of money on their prescriptions. Just show the pharmacy staff your card or coupon when it’s time to pick up your prescription or refill. 

RELATED: How do I use the SingleCare app?

Medicare Extra Help

The Social Security Administration’s Extra Help program helps Medicare patients with costs like deductibles and copays for prescription drugs. Medicare beneficiaries can apply for Extra Help anytime, even if they’ve already enrolled in a Medicare Part D plan.

Is there a cheaper alternative to Dupixent?

Eucrisa and Opzelura are two cheaper Dupixent alternatives for atopic dermatitis. Ask your healthcare provider if they are appropriate for you. Some natural alternatives may provide relief as well. 

1. Eucrisa (crisaborole) ointment

Eucrisa is a topical ointment that can be used to treat mild to moderate AD in adults and children 3 months of age and older. Eucrisa, made by Pfizer, is part of the PDE-4 inhibitor drug class. It decreases the immune response that causes eczema. The average cost is approximately $1,057 for one 60-gm tube of Eucrisa 2% without insurance. However, you can use an Eucrisa coupon from SingleCare to reduce your price to about $681.

2. Opzelura (ruxolitinib) cream

Opzelura is a topical cream used for short-term treatment of mild-to-moderate AD in adults and adolescents 12 years of age and older when topical treatments do not adequately control symptoms. It is a Janus kinase (JAK) inhibitor, targeting specific enzymes to reduce inflammation and relieve symptoms. On average, Opzelura retails at $3,041 for one 60-gm tube of Opzelura 1.5%. However, you can get it for $1,903, depending on your choice of pharmacy.  

3. Natural alternatives to Dupixent

Natural approaches like dietary changes can help people whose skin becomes inflamed due to reacting to food, according to the National Eczema Association. In such cases, avoiding gluten and dairy may help. It may also help to increase your intake of vitamin D since low levels of the vitamin are related to cases of severe eczema. Other options include topical moisturizers made of coconut oil or sunflower seed oil. Some people find success with acupuncture or hypnosis. 

Natural alternatives are not substitutes for medications, but they can help manage symptoms when used in conjunction with medication. Always consult your healthcare provider for medical advice about whether it is safe to try alternative treatments in combination with your medications. 

The SingleCare prices in this article are the most accurate at the time of publishing in ZIP code 23666 as of March 20, 2026. Prices vary by pharmacy. Visit our Dupixent coupon page for updated Dupixent prices near you.