Desvenlafaxine ER Coupons & Prices

Pristiq

Desvenlafaxine ER is a generic prescription drug used to treat major depressive disorder. The average retail price of Desvenlafaxine ER is around $337.21 for 30, 100mg tablet extended release 24 hours. Pay $18.25 for 30, 100mg tablet extended release 24 hours of generic Desvenlafaxine ER by using a SingleCare Desvenlafaxine ER coupon. This coupon can be redeemed for immediate savings at participating local pharmacies.

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7 tablet extended release 24 hour25mgEdit

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Desvenlafaxine ER coupon at Kroger Pharmacy
$21.25
$ 18.25
$3 off with signupwith signup

Show this free card to your pharmacist.

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Desvenlafaxine ER coupon at Harris Teeter Pharmacy
$21.25
$ 18.25
$3 off with signupwith signup

Save an extra $3 on any eligible prescription! Sign up for free

Members can save even more
and it's free to join

Desvenlafaxine ER coupon at Food Lion Pharmacy
$ 25.13
Desvenlafaxine ER coupon at Walmart Neighborhood Market Pharmacy
$28.47
$ 25.47
$3 off with signupwith signup
Desvenlafaxine ER coupon at Walmart Pharmacy
$28.47
$ 25.47
$3 off with signupwith signup
Desvenlafaxine ER coupon at CVS Pharmacy
$29.70
$ 26.70
$3 off with signupwith signup
$ 26.93
$30.18
$ 27.18
$3 off with signupwith signup
$ 31.99

About SingleCare Pricing

SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.

Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.

Prices updated: 12/05/2025

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About Desvenlafaxine ER

Desvenlafaxine ER is a generic prescription drug used to treat major depressive disorder. The average retail price of Desvenlafaxine ER is around $337.21 for 30, 100mg tablet extended release 24 hours. Pay $18.25 for 30, 100mg tablet extended release 24 hours of generic Desvenlafaxine ER by using a SingleCare Desvenlafaxine ER coupon. This coupon can be redeemed for immediate savings at participating local pharmacies.

Desvenlafaxine ER Price History & Information

Price History for Desvenlafaxine Succinate Er (Generic) & Pristiq (Brand)

30 count, tablet extended release 24 hour, 100mg

Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.

Average 1-Month Prices for Desvenlafaxine Succinate Er (Generic) & Pristiq (Brand)

30 count, tablet extended release 24 hour, 100mg
PharmacyPristiq Retail PriceDesvenlafaxine Succinate Er Retail PriceDesvenlafaxine Succinate Er SingleCare Price
CVS Pharmacy-$209.10$51.60
Walmart$520.20$144.00$22.60
Walgreens$567.90$222.60$120.24
Kroger Pharmacy-$341.87$18.60
Albertsons Pharmacy-$318.64$46.54

These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.

About Desvenlafaxine ER

Desvenlafaxine ER is a generic prescription drug used to treat major depressive disorder. The average retail price of Desvenlafaxine ER is around $337.21 for 30, 100mg tablet extended release 24 hours. Pay $18.25 for 30, 100mg tablet extended release 24 hours of generic Desvenlafaxine ER by using a SingleCare Desvenlafaxine ER coupon. This coupon can be redeemed for immediate savings at participating local pharmacies.

Desvenlafaxine ER FAQs

How much does Desvenlafaxine ER cost without insurance?

Usually the cost of Desvenlafaxine ER without insurance coverage is around $337.21 for 30, 100mg tablet extended release 24 hours. SingleCare can help you to save on this total with a Desvenlafaxine ER coupon. Pay as little as $18.25 for 30, 100mg tablet extended release 24 hours of generic Desvenlafaxine ER when you use SingleCare’s Desvenlafaxine ER coupon at participating drugstores.

How much does Desvenlafaxine ER cost with insurance?

The cost of Desvenlafaxine ER with insurance may vary based on the type of insurance coverage plan that you are enrolled in. Contact your insurance provider directly to find out exactly how much Desvenlafaxine ER costs under your current insurance plan. SingleCare can help you easily save on your Desvenlafaxine ER purchases. Pay $18.25 for 30, 100mg tablet extended release 24 hours of generic Desvenlafaxine ER when you use SingleCare’s Desvenlafaxine ER coupon card.

Does Medicare cover Desvenlafaxine ER, and how much does it cost?

Desvenlafaxine ER is usually covered by Medicare Part D and Medicare Advantage plans. The average copay for Desvenlafaxine ER with Medicare varies. Spend $18.25 instead of $337.21 for 30, 100mg tablet extended release 24 hours of Desvenlafaxine ER when you use your SingleCare savings card at participating local pharmacies. Talk to your local pharmacist today to find out more about saving with SingleCare.

How much does Desvenlafaxine ER cost with Medicaid?

Desvenlafaxine ER is usually covered by Medicaid, but coverage may vary by state and Medicaid plan. Depending on the state, Medicaid copays typically range from $0 to $3. Contact your Medicaid plan to see if Desvenlafaxine ER is covered. 

How to save on Desvenlafaxine ER

You can pay as little as $18.25 for 30, 100mg tablet extended release 24 hours of Desvenlafaxine ER with a SingleCare coupon. If you sign up for SingleCare’s loyalty program, you can save even more. 

If you still have difficulty affording Desvenlafaxine ER, other ways can help you save. These include:

  • Applying for Medicaid, depending on eligibility requirements

  • Enrolling in commercial insurance

  • Asking your healthcare provider for free samples

  • Enrolling in patient assistance programs, depending on availability and eligibility

  • Checking for manufacturer coupons

  • Enrolling in Medicare if you are 65 years or older

  • Shopping around to see the cost of Desvenlafaxine ER at different pharmacies

What is the brand name of Desvenlafaxine ER?

Desvenlafaxine ER is a generic prescription medication. The brand-name version of this drug is Pristiq.

Is there a cheaper alternative to Desvenlafaxine ER? 

The cost of Desvenlafaxine ER may vary based on the pharmacy and insurance plans. Other antidepressants may be a more affordable alternative. These include serotonin and norepinephrine reuptake inhibitors (SNRIs), such as venlafaxine and duloxetine, and selective serotonin reuptake inhibitors (SSRIs), such as fluoxetine and sertraline. Talk to your healthcare provider to see which medication works best for you.

Where are Desvenlafaxine ER coupons from SingleCare accepted?

SingleCare is accepted at most national pharmacies and grocers, including the following:

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