Learn more about difluprednate
Difluprednate is a Ophthalmic Steroids class medicine that is manufactured by Amneal Pharmaceuticals. The average retail price for Difluprednate is $303.36 per 1, 5ml of 0.05% bottle, but you can pay just $48.76 for 1, 5ml of 0.05% bottle when you use a SingleCare savings card. Difluprednate is a generic medicine; Durezol is the branded form of Difluprednate.
Edit your dosage
Get alerted when the price
changes more than 10%
changes more than 10%
1 bottle, 5ml of 0.05%Edit
$51.76
$ 48.76
$3 off with signupwith signup
Show this free card to your pharmacist.
$61.56
$ 58.56
$3 off with signupwith signup
$61.56
$ 58.56
$3 off with signupwith signup
$80.90
$ 77.90
$3 off with signupwith signup
$118.54
$ 115.54
$3 off with signupwith signup
$118.54
$ 115.54
$3 off with signupwith signup
$ 118.00
$ 119.99
$124.36
$ 121.36
$3 off with signupwith signup
About SingleCare Pricing
SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.
Prices updated: 12/05/2025
Members save the most
Save big on your prescriptions
with the free SingleCare app.
4.8 average ratingText a link to get the app
About Difluprednate
Difluprednate is a Ophthalmic Steroids class medicine that is manufactured by Amneal Pharmaceuticals. The average retail price for Difluprednate is $303.36 per 1, 5ml of 0.05% bottle, but you can pay just $48.76 for 1, 5ml of 0.05% bottle when you use a SingleCare savings card. Difluprednate is a generic medicine; Durezol is the branded form of Difluprednate.
Learn more about difluprednate
Difluprednate Price History & Information
Price History for Difluprednate (Generic) & Durezol (Brand)
1 count, bottle, 5ml of 0.05%Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.
Average 1-Month Prices for Difluprednate (Generic) & Durezol (Brand)
1 count, bottle, 5ml of 0.05%| Pharmacy | Durezol Retail Price | Difluprednate Retail Price | Difluprednate SingleCare Price |
|---|---|---|---|
| CVS Pharmacy | - | $200.00 | $98.75 |
| Walmart | $266.85 | $151.08 | $49.68 |
| Walgreens | $267.00 | $137.40 | $83.68 |
| Kroger Pharmacy | $267.00 | $208.62 | $118.55 |
| Albertsons Pharmacy | $276.70 | $148.70 | $120.60 |
These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.
About Difluprednate
Difluprednate is a Ophthalmic Steroids class medicine that is manufactured by Amneal Pharmaceuticals. The average retail price for Difluprednate is $303.36 per 1, 5ml of 0.05% bottle, but you can pay just $48.76 for 1, 5ml of 0.05% bottle when you use a SingleCare savings card. Difluprednate is a generic medicine; Durezol is the branded form of Difluprednate.
Difluprednate FAQs
How much is Difluprednate with SingleCare?
Difluprednate costs $48.76 for 1, 5ml of 0.05% bottle with a free Difluprednate coupon from SingleCare. But, you could reduce this cost more depending on your Rx details. Use the dropdown menu above to enter your Rx info (i.e., brand/generic, form, dosage, quantity) to get the most accurate prices of Difluprednate with SingleCare at a pharmacy near you.
How much does Difluprednate cost without insurance?
The average retail price of Difluprednate without health insurance is $303.36 per 1, 5ml of 0.05% bottle though you can save money using a SingleCare Difluprednate coupon to pay only $48.76 for 1, 5ml of 0.05% bottle of Difluprednate. Those without health insurance can always use SingleCare for free Difluprednate discounts. By getting Difluprednate, you typically save on your medication compared with using Durezol - the branded form of Difluprednate, which usually costs dramatically more than Difluprednate.
How much does Difluprednate cost with insurance?
Every insurance program is unique and may or may not cover Difluprednate. The cost of Difluprednate with insurance coverage varies according to your plan - reach out to your insurance company for definitive drug coverage and copay guidance. If your insurance does not cover Difluprednate, you can use SingleCare to get a better rate on Difluprednate at your local pharmacies. In addition, you can also use SingleCare coupons if you have Medicare or Medicaid. If Medicare or Medicaid doesn’t provide coverage your Difluprednate order, use SingleCare instead. Go to the SingleCare website or app to compare the lowest price of Difluprednate with SingleCare versus your Difluprednate cost with insurance or Medicare.
How to use SingleCare for Difluprednate
SingleCare is accepted at most major pharmacies and grocery stores, including Walgreens, Kroger, Walmart, CVS, Safeway, and more. You can text, email, print, or save your free Difluprednate coupon to your mobile wallet and show a pharmacist when you pick up your prescription.
What is the brand name of Difluprednate?
Difluprednate is the generic version of Durezol and is significantly cheaper than Durezol. The SingleCare price of Difluprednate is $48.76 per 1, 5ml of 0.05% bottle, which typically is dramatically cheaper than the typical price for Durezol but has the same active ingredients.
Where are Difluprednate coupons from SingleCare accepted?
SingleCare is accepted at most national pharmacies and grocers, including the following:
Subscribe to our savings newsletter
Health education, drug info, wellness & more
By clicking 'Subscribe', I agree to SingleCare's Terms & Conditions.
