Durezol is a prescription medication used to treat inflammation and pain caused by eye surgery or certain eye problems. It works as an ophthalmic corticosteroid that blocks certain substances that cause inflammation. The generic version of Durezol is difluprednate ophthalmic emulsion. The average retail price of Durezol is $278.84 for 1, 5ml of 0.05% bottle. However, with a SingleCare Durezol coupon, you could reduce the retail price to $48.76 for 1, 5ml of 0.05% bottle at participating pharmacies.
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SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
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Prices updated: 12/05/2025
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Durezol is a prescription medication used to treat inflammation and pain caused by eye surgery or certain eye problems. It works as an ophthalmic corticosteroid that blocks certain substances that cause inflammation. The generic version of Durezol is difluprednate ophthalmic emulsion. The average retail price of Durezol is $278.84 for 1, 5ml of 0.05% bottle. However, with a SingleCare Durezol coupon, you could reduce the retail price to $48.76 for 1, 5ml of 0.05% bottle at participating pharmacies.
Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.
| Pharmacy | Durezol Retail Price | Difluprednate Retail Price | Difluprednate SingleCare Price |
|---|---|---|---|
| CVS Pharmacy | - | $200.00 | $98.75 |
| Walmart | $266.85 | $151.08 | $49.68 |
| Walgreens | $267.00 | $137.40 | $83.68 |
| Kroger Pharmacy | $267.00 | $208.62 | $118.55 |
| Albertsons Pharmacy | $276.70 | $148.70 | $120.60 |
These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.
Durezol is a prescription medication used to treat inflammation and pain caused by eye surgery or certain eye problems. It works as an ophthalmic corticosteroid that blocks certain substances that cause inflammation. The generic version of Durezol is difluprednate ophthalmic emulsion. The average retail price of Durezol is $278.84 for 1, 5ml of 0.05% bottle. However, with a SingleCare Durezol coupon, you could reduce the retail price to $48.76 for 1, 5ml of 0.05% bottle at participating pharmacies.
Without insurance, the average cost of Durezol is $278.84 for 1, 5ml of 0.05% bottle. Prices can fluctuate based on the pharmacy location and the quantity prescribed. You may want to compare prices at local pharmacies. SingleCare offers a Durezol coupon that may help you save, bringing the cost down to $48.76 for 1, 5ml of 0.05% bottle at participating pharmacies.
Insurance coverage for Durezol can vary depending on your plan and the prescribed quantity. In many cases, you may be responsible for a copay or coinsurance amount, which may affect the final out-of-pocket cost. Contact your health insurance provider or pharmacist to determine the total cost of Durezol with insurance. You may be able to save more money with a SingleCare Durezol coupon than with your insurance plan.
Coverage for Durezol under Medicare will vary by plan and prescription quantity. Check with your plan’s provider or pharmacist to determine the cost of Durezol with Medicare. If you lack adequate Medicare coverage, a SingleCare Durezol coupon could help you get the lowest prices. In some cases, using the SingleCare card could save you more than using Medicare.
There are currently no manufacturer coupons for Durezol. However, individuals facing financial hardship may find patient assistance programs offered by non-profits or national-level programs. For example, the Patient Access Network Foundation (PAN) is a third-party organization that may offer financial assistance for Durezol. Patient assistance programs may often provide prescription medications at a reduced cost or free of charge to eligible patients.
Another potential way to save on Durezol is through SingleCare. SingleCare offers a prescription discount card that may reduce the cost of numerous prescription medications. With a SingleCare Durezol coupon, you may be able to obtain the medicine for $48.76 for 1, 5ml of 0.05% bottle. To access a discounted price, simply present the SingleCare card at a participating pharmacy.
A generic equivalent is currently available for Durezol in the United States. The generic version of Durezol is difluprednate emulsion.
Durezol is an eye medication used to treat inflammation and pain associated with eye surgery and certain eye problems. It may be prescribed after cataract surgery to help the eye heal and reduce discomfort. Durezol contains the active ingredient difluprednate and works by altering the body's immune response to reduce inflammation and pain in the eye.
Durezol is available as a 0.05% difluprednate ophthalmic emulsion. The prescribed dosage will depend on the medical condition being treated. For pain and inflammation after eye surgery, the medication is usually instilled into the affected eye four times daily for the first two weeks. The medication is then reduced to twice daily for one week and further reduced over time. Durezol is instilled into the affected eye four times daily for two weeks to treat endogenous anterior uveitis, with the dosage being gradually reduced over time. Contact a healthcare provider for the appropriate way to administer Durezol.
Durezol may cause side effects that can range from mild to severe. In many cases, side effects are mild and temporary. Common side effects of {{drug} include:
Eye pain
Blurred vision
Dry or itchy eyes
Sensitivity to light
The use of steroids in the eyes may be linked to serious adverse effects such as infections, cataracts, and glaucoma. Consult a healthcare provider for medical advice and additional information on other potential precautions or warnings.
Durezol eye drops are not typically recommended for long-term use. The long-term use of Durezol and other ophthalmic corticosteroids should be monitored by a healthcare provider. Long-term use may increase the risk of complications like optic nerve damage, vision problems, and infections. Consult your healthcare provider if you have any questions or concerns about using Durezol.
There is currently no known shortage of Durezol from Novartis Pharmaceuticals, the primary manufacturer of Durezol. However, availability may vary by location and pharmacy. You may want to call your local pharmacy for the most accurate and up-to-date information. You can also check the FDA drug shortage database for additional information. Generic versions of Durezol may be more available and accessible than the brand-name version.
Gerardo Sison, Pharm.D., graduated from the University of Florida. He has worked in both community and hospital settings, providing drug information and medication therapy management services. As a medical writer, he hopes to educate and empower patients to better manage their health and navigate their treatment plans.
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Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
Blog articles are not medical advice. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911.
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© 2025 SingleCare Administrators. All rights reserved