What is Lumizyme: Uses, Warnings & Interactions

Updated May 14, 2025  •  Published Dec 31, 2020

Lumizyme overview

BRAND NAMES:

  • Lumizyme, Myozyme

Generic Names:

  • Lumizyme

Uses:

  • Treats Pompe disease.

Therapeutic Classes:

  • Enzyme Replacement

Forms:

  • Injectable

How it’s taken:

  • By injection

What is Lumizyme used for?

Lumizyme is a prescription-only medication that is prescribed to patients who have deficient enzymes within their body. This drug can also be used to treat patients diagnosed with Pompe disease. Lumizyme works by replacing the missing enzymes to help patients with breaking down carbohydrates within their digestive system. Lumizyme is taken by both adults and children who are at least eight years old.

What form(s) does Lumizyme come in

  • Injectable

What are common Lumizyme doses?

  • Solution Reconstituted 50MG

Common Lumizyme prescriptions

  • Lumizyme
    50mg solution reconstituted

How to take Lumizyme

  • Injection routeYour doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein.

  • Injection routeA nurse or other health provider will give you this medicine.

  • This medicine must be given slowly, so the needle will remain in place for a few hours.

  • Missed dose: Injection routeCall your doctor or pharmacist for instructions.

  • Injection routeYour doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein.

  • Injection routeA nurse or other health provider will give you this medicine.

  • This medicine must be given slowly, so the needle will remain in place for a few hours.

  • Missed dose: Injection routeCall your doctor or pharmacist for instructions.

What to do if you miss a dose of Lumizyme

Lumizyme contraindications

  • This medicine is not right for everyone. You should not receive it if you had an allergic reaction to alglucosidase alfa.

Lumizyme warnings

  • Tell your doctor if you are pregnant or breastfeeding, or if you have heart disease or lung disease.

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

  • Fast, slow, or pounding heartbeat

  • Fever, chills, sore throat, body aches

  • Lightheadedness, dizziness, fainting

Lumizyme interactions

  • Tell your doctor if you are pregnant or breastfeeding, or if you have heart disease or lung disease.

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

Lumizyme side effects

Serious Side Effects

  • Lightheadedness, dizziness, fainting

  • Fast, slow, or pounding heartbeat

  • Fever, chills, sore throat, body aches

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Chest pain, trouble breathing, cold sweats, blue lips, fingernails, or skin

Less Serious Side Effects

  • Increased sweating

  • Nausea, vomiting, diarrhea, constipation

  • Pain, itching, burning, swelling, or a lump under your skin where the needle is placed

  • Warmth or redness in your face, neck, arms, or upper chest

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