What is Neurontin? Uses, warnings & side effects

Updated May 14, 2025  •  Published Dec 30, 2020

Neurontin is a brand-name prescription anticonvulsant that has many uses in healthcare. Its active ingredient, gabapentin, slows down nerve activity, particularly nerves involved with pain. Neurontin is an oral medication available as a tablet, capsule, and oral solution. Doses are taken three times daily.

Neurontin overview

BRAND NAMES:

  • Neurontin

Generic Names:

  • Gabapentin

Uses:

  • Treats seizures and nerve pain caused by shingles

Therapeutic Classes:

  • Anticonvulsant, neuropathic pain agent

Forms:

  • Capsule, tablet, oral solution (liquid)

How it’s taken:

  • By mouth

What is Neurontin used for?

Neurontin has many FDA-approved and unapproved uses in medicine. The FDA has approved Neurontin to relieve pain due to shingles and as an add-on treatment for partial-onset seizures. Healthcare professionals commonly use it off-label for other medical conditions, particularly nerve pain, such as spinal nerve pain, diabetic neuropathy, fibromyalgia, trigeminal neuralgia, and migraine prevention. It’s also used off-label for hot flashes, alcohol withdrawal, bipolar disorder, posttraumatic stress disorder (PTSD), anxiety, itchiness (pruritus), tremors, and muscle spasms due to multiple sclerosis.

What form(s) does Neurontin come in?

  • Capsule

    • 100 mg

    • 300 mg

    • 400 mg

  • Tablet

    • 600 mg

    • 800 mg

  • Oral solution (liquid)

    • 250 mg/5 mL

What are common Neurontin dosages?

  • For partial-onset seizures in adults and children 12 years or older: 300–600 mg taken three times daily

    • For children 5–11 years old: 25-35 mg/kg (11.4-15.9 mg/lb) per day divided into three daily doses

    • For children 3–4 years old: 40 mg/kg (18.2 mg/lb) per day divided into three daily doses

  • For postherpetic neuralgia in adults: 300–600 mg taken three times daily

Find more information about gabapentin dosage, forms, and strengths here.

Neurontin images - What does Neurontin look like?

  • Neurontin
    10 capsules bottle

  • Neurontin
    100 capsules bottle

  • Neurontin
    120 capsules bottle

  • Neurontin
    20 capsules bottle

  • Neurontin
    30 capsules bottle

  • Neurontin
    30 tablets bottle

  • Neurontin
    35 capsules bottle

  • Neurontin
    45 capsules bottle

  • Neurontin
    470ml of 250mg/5ml bottle

  • Neurontin
    50 tablets bottle

  • Neurontin
    60 capsules bottle

  • Neurontin
    90 capsules bottle

  • Neurontin
    100mg capsule

  • Neurontin
    300mg capsule

  • Neurontin
    400mg capsule

  • Neurontin
    600mg tablet

  • Neurontin
    800mg tablet

How to take Neurontin

  • Take your medicine as directed. Your dose may need to be changed several times during therapy. 

  • Please read the Medication Guide that comes in the Neurontin package.

  • For epilepsy, take doses at the same times every day. Do not allow more than 12 hours to pass between doses.

  • Gabapentin can be taken with or without food.

  • How to take gabapentin capsules:

    • Swallow the capsule whole with a glass of water. Do not open, crush, or chew it.

    • In situations where the patient cannot swallow the capsule, the doctor may suggest opening the capsule, sprinkling the contents into a small cup of water, juice, or apple sauce, and taking the dose that way. Ask the doctor before doing this.

    • Store Neurontin capsules at room temperature in a closed, child-safe container.

  • How to take Neurontin tablets:

    • Swallow the tablet whole with a glass of water. Do not crush, break, or chew it.

    • The tablets are scored so they can be divided into two doses. Ask a pharmacist or other healthcare provider how to correctly divide tablets.

    • If you break a tablet into two pieces, use the second half as your next dose. Discard any unused half-tablet after 28 days.

    • Store Neurontin tablets at room temperature in a closed, child-safe container.

  • How to take Neurontin oral solution:

    • Shake the closed bottle well before each use.

    • Measure the oral liquid with a syringe or medicine cup with millimeter markings. 

    • Store Neurontin oral solution in the refrigerator in a securely closed container.

What to do if you miss a dose of Neurontin

  • Take a missed dose as soon as you remember it. If it’s almost time for the next dose, skip the missed dose and take the next dose at the proper time.

  • If Neurontin is being taken for epilepsy, do not miss doses. Never allow more than 12 hours to elapse between doses.

  • Never take extra medicine to make up for a missed dose.

Neurontin contraindications - Who shouldn't take Neurontin?

  • This medicine is not right for everyone. 

  • Do not use it if you have had an allergic reaction to gabapentin.

Neurontin warnings

  • Tell any doctor or other healthcare provider who treats you that you are taking gabapentin. This drug may alter the results of some lab tests. 

  • Regular doctor visits are necessary to check the effectiveness of gabapentin treatment. Keep all appointments.

  • Before starting Neurontin, tell the prescriber if you are pregnant or breastfeeding. The prescriber should also know about your medical situation, particularly if you have: 

    • Any history of depression, mood problems, or suicidal thoughts

    • Kidney problems

    • Breathing problems

    • Diabetes

  • Gabapentin is usually safe but can cause serious problems in some people, including:

    • Suicidal thoughts and behaviors

    • Worsening of depression

    • Impairment resulting in injuries or accidents

    • Neuropsychiatric symptoms in children

    • Severe allergic reactions

  • This medicine may make you dizzy or drowsy. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.

  • Do not stop taking Neurontin doses suddenly. When it’s time to stop taking gabapentin, the prescriber may need to slowly decrease the dose over time.

  • While it’s important to keep medicines out of the reach of children, take extra care with gabapentin.

Neurontin interactions & what to avoid when taking Neurontin

  • To avoid potentially hazardous drug interactions, tell the prescribing healthcare provider about all prescription drugs, over-the-counter medications, and supplements you use, particularly:

  • Do not drink alcohol on the days you take gabapentin.

  • Gabapentin cannot be taken at the same time as an antacid. If you take an antacid, wait at least two hours before you take gabapentin.

Neurontin side effects - How does Neurontin make you feel?

Serious side effects

Neurontin can cause serious side effects. Talk to a doctor if you notice any signs or symptoms of a possible serious side effect, including:

  • Unusual moods or behaviors, thoughts of hurting yourself, feeling depressed

  • Behavior changes, agitation, restlessness, aggression, trouble concentrating, moodiness (especially in children)

  • Increased sleepiness, decreased breathing

  • Blue lips, fingernails, or skin, chest pain, fast heartbeat, trouble breathing

  • Unusual bruising or bleeding

  • Severe tiredness, fatigue, or weakness

  • Sudden muscle pain

  • Yellow skin or eyes

  • Fever, skin rash, swollen neck glands, change in how much or how often you urinate, or bloody or cloudy urine

  • Blistering, peeling, red skin rash

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

Less serious side effects include:

  • Dizziness

  • Drowsiness

  • Headache

  • Loss of coordination or clumsiness

  • Fatigue

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