Trexall is a brand-name prescription drug used to treat leukemia and other types of cancer involving the skin, head, neck, lungs, or other parts of the body. It can also be used to treat rheumatoid arthritis and psoriasis. Trexall is an immunosuppressant and chemotherapy drug that contains methotrexate. The average retail price of Trexall is $213.22, but this price may be reduced to $182.45 with a SingleCare Trexall coupon.
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SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.
Prices updated: 12/05/2025
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Trexall is a brand-name prescription drug used to treat leukemia and other types of cancer involving the skin, head, neck, lungs, or other parts of the body. It can also be used to treat rheumatoid arthritis and psoriasis. Trexall is an immunosuppressant and chemotherapy drug that contains methotrexate. The average retail price of Trexall is $213.22, but this price may be reduced to $182.45 with a SingleCare Trexall coupon.
Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.
| Pharmacy | Trexall Retail Price | Trexall SingleCare Price |
|---|---|---|
| Walgreens | $236.80 | $197.88 |
| Kroger Pharmacy | $221.48 | $185.44 |
These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.
Trexall is a brand-name prescription drug used to treat leukemia and other types of cancer involving the skin, head, neck, lungs, or other parts of the body. It can also be used to treat rheumatoid arthritis and psoriasis. Trexall is an immunosuppressant and chemotherapy drug that contains methotrexate. The average retail price of Trexall is $213.22, but this price may be reduced to $182.45 with a SingleCare Trexall coupon.
Trexall can cost an average cash price of $213.22. That same prescription could cost $182.45 per 4, 10mg tablets with a SingleCare prescription savings card. You can use a free discount card from SingleCare at participating pharmacies.
The copay cost of Trexall will depend on your insurance plan. Ask your pharmacist to compare your Trexall insurance copay to your price with a SingleCare Trexall coupon. You may save more money with SingleCare than with your insurance.
Medicare Advantage and Medicare Part D prescription drug insurance plans may help provide coverage for Trexall, but the copay may be high. If you don't have coverage for Trexall or your copay costs are high, you could use a SingleCare Trexall coupon potentially save more money than you would with Medicare. With SingleCare, the lowest price of Trexall is $182.45.
Trexall is a brand-name prescription drug that contains methotrexate. Generic versions of Trexall are available.
Trexall is a brand-name prescription drug used to treat leukemia and cancers of the skin, head, neck, lungs, and other parts of the body. It can also be used to treat rheumatoid arthritis and psoriasis.
Trexall is an immunosuppressant and chemotherapy drug that contains methotrexate. It works by slowing down activity of the immune system and slowing the growth of abnormal cells associated with cancer. Trexall is part of a class of drugs called antimetabolites.
This medication comes as an oral tablet. It should only be taken as prescribed by a doctor or healthcare provider. Tell your provider about other medical conditions you may have and other medications you may be taking, including prescription medications, over-the-counter drugs, and herbal supplements, before taking Trexall.
Common side effects of Trexall include, but are not limited to, drowsiness, dizziness, fatigue, headache, decreased appetite, hair loss, and swelling of the gums. Serious side effects of Trexall include organ system toxicity, changes in menstruation or fertility, abnormal blood cell counts, and decreased liver or kidney function. Seek medical attention if you experience signs or symptoms of an allergic reaction, including rash, hives, difficulty breathing, or swelling of the face or throat. Consult a healthcare provider if any side effects develop, persist, or worsen.
This is not a complete list of side effects. Consult your doctor or healthcare professional for additional information and medical advice regarding other possible side effects or drug interactions. You can report negative side effects to the FDA.
Gerardo Sison, Pharm.D., graduated from the University of Florida. He has worked in both community and hospital settings, providing drug information and medication therapy management services. As a medical writer, he hopes to educate and empower patients to better manage their health and navigate their treatment plans.
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Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
Blog articles are not medical advice. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911.
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© 2025 SingleCare Administrators. All rights reserved