Key takeaways
The average cost of a one-month supply of Zepbound without insurance is over $1,500.
Using a free SingleCare coupon for Zepbound can save you hundreds of dollars on your prescription.
Other ways to save money on Zepbound include using manufacturer savings cards, asking for an insurance exception, and comparing pharmacy prices.
If you’ve been struggling to lose weight despite lifestyle changes like diet and exercise, your healthcare provider may recommend a medication like Zepbound (tirzepatide). It works by reducing cravings and overeating, contributing to weight loss.
Zepbound is an injectable medication that is approved by the Food and Drug Administration (FDA) to promote and maintain weight loss in adults and to treat moderate to severe obstructive sleep apnea in adults with obesity. No generic version is available, and insurance coverage varies, so some people face high out-of-pocket costs for Zepbound. Fortunately, Zepbound savings cards, coupons, and programs can lower the price.
How much does Zepbound cost?
If you’re paying cash, the average retail price for a 28-day supply of Zepbound without insurance is about $1,509 for four 0.5 mL pens with a 2.5 mg/0.5 mL dose. The exact cost of Zepbound can vary based on your location, pharmacy, health insurance coverage, and dosage.
Does commercial health insurance cover Zepbound?
Many health insurance plans don’t cover Zepbound, but some might, especially if it is for treating obstructive sleep apnea as opposed to treating obesity alone. If Zepbound is covered, it’s likely to be classified as a Tier 3 drug or higher, indicating it’s a higher-cost name-brand drug. Typically, your copay or coinsurance increases with higher drug tiers.
If you have commercial insurance coverage, the best way to find out how much you’ll pay for Zepbound is to contact the company to determine your plan’s specific coverage. Each plan has a formulary or list of covered medications, as well as eligibility requirements. For example, you may be required to meet the prescribing criteria given by Zepbound’s manufacturer, Eli Lilly:
- Patients with obesity with a BMI of 30 or more
- Patients who are overweight with a BMI of 27 or more and one weight-related health condition, such as hypertension (high blood pressure), cardiovascular disease, Type 2 diabetes, or high cholesterol
- Patients with moderate to severe obstructive sleep apnea (OSA) and obesity
Many insurance companies don’t cover GLP-1 drugs for weight loss because they consider them cosmetic uses of medications, according to the Obesity Medicine Association. Even if they do, it’s important to check to see if prior authorization is required.
Note that tirzepatide, the active ingredient in Zepbound, is also sold as Mounjaro for the treatment of Type 2 diabetes. Mounjaro is more likely to be covered by insurance, but not for an off-label use like weight loss. Your healthcare provider must submit a prior authorization request on your behalf to show that Mounjaro is medically necessary for your diabetes treatment.
RELATED: Does United Healthcare cover Zepbound?│Does Aetna cover Zepbound?
Does Medicare cover Zepbound?
“Medicare will not cover any weight-loss medications, including Zepbound,” says Erika Gray, Pharm.D., chief medical officer and co-founder of Toolbox Genomics, a DNA and epigenetic testing company. In fact, coverage of obesity medications was banned by the Medicare Modernization Act of 2003. Some Medicare plans may cover Zepbound when it’s prescribed for sleep apnea. Check with your plan to verify coverage.
Does Medicaid cover Zepbound?
Medicaid may cover weight-loss drugs like Zepbound or Wegovy, but coverage varies by state. Most state Medicaid programs don’t cover Zepbound for obesity unless the beneficiary has obstructive sleep apnea (OSA) in addition to obesity.
That said, state Medicaid programs could access lower prices for GLP-1 drugs like Zepbound and Ozempic in 2026 through new pricing agreements. Lower prices could make it more affordable for states to cover obesity medications.
Can I get Zepbound for free?
“It is uncommon to get Zepbound for completely free,” Dr. Gray says. Even if you have health insurance, Zepbound may not be covered.
How to save money on Zepbound
Whether you have insurance or not, there are ways to save on Zepbound.
1. Free Zepbound coupons
SingleCare is a prescription discount service that offers up to 80% off over 10,000 medications. With a SingleCare discount card, you can potentially save hundreds of dollars on your prescription costs. SingleCare coupons can’t be combined with insurance or other discounts, so they’re best for people who don’t qualify for other savings programs or whose insurance doesn’t cover Zepbound.
Getting and using a SingleCare card is easy:
- Search for Zepbound on the SingleCare app or website.
- Enter your ZIP code.
- Choose your Zepbound dosage and quantity from the drop-down menus.
- Compare discounted prices at participating pharmacies.
- Click or tap “Get free coupon” to generate a reusable SingleCare prescription discount card.
- Text, email, or print the card to save it for later. Or, sign up for a free SingleCare account to save the coupon and get an extra $3 member bonus on prescriptions.
- Make sure your prescription is transferred to the pharmacy where you plan to use your coupon.
- Show the pharmacy staff your SingleCare coupon when collecting your Zepbound prescription.
Save up to 80% on Zepbound with SingleCare
Different pharmacies offer different prices for the same medication. SingleCare helps find the best price for you.
2. Lilly Zepbound savings card
Eli Lilly and Company, the manufacturer of Zepbound, offers a savings card for people who have commercial drug insurance, are over the age of 18, live in the U.S., and have a legitimate Zepbound prescription for an FDA-approved indication.
The amount you save depends on whether your insurance plan covers Zepbound:
- If Zepbound is covered by your insurance: Pay as little as $25 for 4, 8, or 12 Zepbound pens with a maximum savings of $1,950 per calendar year.
- If Zepbound isn’t covered by your insurance: Save up to $469 for 4 Zepbound pens, with a maximum savings of $6,097 per calendar year.
Other terms and conditions apply. You can use the Lilly Zepbound savings card up to 13 times per year. Each card expires at the end of the calendar year, but you can reapply annually. Keep in mind that prior authorization is usually required unless you are using self-pay, and it’s important to read the terms and conditions.
Dr. Gray notes that Medicare patients don’t qualify for manufacturer savings cards because federal or government insurance is an exclusion.
3. Zepbound Self Pay Journey Program
If you don’t have insurance or your health plan doesn’t cover Zepbound, consider using Lilly’s Self Pay Journey Program to get exclusive discounts.
Only single-dose vials are available with the Zepbound Self Pay Journey Program. If you prefer an autoinjector pen, consider using a SingleCare coupon instead.
The discounted cost of Zepbound depends on the dosage. You may lose eligibility for the Zepbound Self Pay Journey Program if you wait more than 45 days to refill your prescription through LillyDirect.
4. Insurance exception requests
If your health insurance plan doesn’t cover Zepbound, you can ask for coverage anyway. This is known as an exception request, and it’s filed on your behalf by your healthcare provider. Your request may be granted if there’s enough evidence that Zepbound is medically necessary and no alternatives are appropriate.
5. Comparing prices
Prices can vary widely depending on which pharmacy you choose. To get the best price, comparing prices between pharmacies is always recommended. SingleCare makes it easy to compare prices near you.
Is there a cheaper alternative to Zepbound?
Yes. Although diet (eating fewer calories) and exercise are the best ways to lose weight consistently, there are cheaper alternatives to Zepbound that your healthcare provider may consider if they recommend a prescription weight-loss medication.
If you’re specifically interested in a GLP-1 for chronic weight management, consider liraglutide. It’s the generic version of Saxenda, which is approved for those who are obese or overweight with a weight-related health condition like high blood pressure or high cholesterol. Even if you have to pay out of pocket for liraglutide, a SingleCare coupon can reduce the price to $157 for one 18 mg/3 mL 3 mL pen or $697 for five pens (a one-month supply).
Some insurance plans don’t cover Zepbound but do cover Wegovy (semaglutide), another GLP-1 approved for weight loss. According to Fernando Ovalle Jr., MD, a double board-certified obesity medicine specialist based in Orlando, Florida, people tend to lose less weight with Wegovy (15%) compared to Zepbound (20%). However, he says both “substantially outperform older oral anti-obesity medications like phentermine-topiramate (Qsymia), naltrexone-bupropion (Contrave), or orlistat (Xenical or Alli), which generally produce 5% to 10% weight loss.”
Although they’re less effective, older appetite suppressants and lipase inhibitors are more affordable than Zepbound.
Zepbound alternatives |
|
|---|---|
| Prescription | Compare prices |
| Adipex-P (phentermine) | Check Adipex-P prices |
| Contrave | Check Contrave prices |
| Ozempic (semaglutide) | Check Ozempic prices |
| Qsymia | Check Qsymia prices |
| Saxenda (liraglutide) | Check Saxenda prices |
| Wegovy (semaglutide) | Check Wegovy prices |
| Xenical (orlistat) | Check Xenical prices |
Bottom line
Price isn’t the only factor to consider when choosing a prescription drug for weight loss. Talk to your healthcare provider about the potential side effects, contraindications, long-term risks, drug interactions, dosage schedules, and efficacy of Zepbound alternatives. If Zepbound is the best choice for you, know that you don’t have to pay the full retail price thanks to several savings options.
The SingleCare prices in this article are the most accurate at the time of publishing in ZIP code 23666 as of March 10, 2026. Prices vary by pharmacy. Visit our Zepbound coupon page for updated Zepbound prices near you.
- FDA approves new medication for chronic weight management, U.S. Food & Drug Administration (2023)
- Getting patients started, Eli Lilly and Company
- Does insurance cover weight loss medication?, Obesity Medicine Association (2023)
- Why doesn’t Medicare cover drugs like Ozempic for weight loss?, Marketplace (2024)
- Reducing obesity, Medicaid.gov
- State coverage and reimbursement of antiobesity medications in Medicaid, JAMA (2024)
- 3 quick steps to learn how you could save on Zepbound, Eli Lilly and Company
- Steps for losing weight, Centers for Disease Control and Prevention (2025)
- Trump announces deals with Lilly, Novo to cut weight loss drug prices, AJMC (2025)
- Mounjaro drug label information, DailyMed (2025)